In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition

Detalhes bibliográficos
Autor(a) principal: Pádua, Ana Sofia
Data de Publicação: 2023
Outros Autores: Gavinho, Sílvia Rodrigues, Vieira, Tânia, Hammami, Imen, Silva, Jorge Carvalho, Borges, João Paulo, Graça, Manuel Pedro Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/162722
Resumo: Funding Information: FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985. Publisher Copyright: © 2023 by the authors.
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spelling In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM DepositionBioglass 45S5ceriumCoBlastcopperhydroxyapatiteimplant coatingzincSurfaces and InterfacesSurfaces, Coatings and FilmsMaterials ChemistrySDG 3 - Good Health and Well-beingFunding Information: FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985. Publisher Copyright: © 2023 by the authors.Bone replacement is one of the major medical procedures in the oral surgery field due to the progressive ageing population and to illness or trauma in younger age groups. The use of implants without biological activity and effective osseointegration increases the chances of implant failure. This work aims to improve the interaction between implants and bone by using Bioglass 45S5 (BG)/hydroxyapatite (HAp) mixtures, including copper-, zinc-, and cerium-doped BG, as well as co-doping by the mentioned metals, as coatings produced by the CoBlastTM technique. All coatings present a uniform coverage of the Ti-6Al-4V substrate. Furthermore, in vitro testing using human osteosarcoma Saos-2 cells indicated that BG/HAp coatings have no cytotoxic effect, and the used of doping agents did not alter cell adhesion, proliferation, or alkaline phosphatase (ALP) expression when compared to undoped coating. These results demonstrate that BG/HAp by CoBlastTM can be a solution to improve implants’ osseointegration.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisDF – Departamento de FísicaRUNPádua, Ana SofiaGavinho, Sílvia RodriguesVieira, TâniaHammami, ImenSilva, Jorge CarvalhoBorges, João PauloGraça, Manuel Pedro Fernandes2024-01-24T17:08:59Z2023-10-162023-10-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13application/pdfhttp://hdl.handle.net/10362/162722eng2079-6412PURE: 82011332https://doi.org/10.3390/coatings13101775info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:45:41Zoai:run.unl.pt:10362/162722Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:02.860639Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
title In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
spellingShingle In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
Pádua, Ana Sofia
Bioglass 45S5
cerium
CoBlast
copper
hydroxyapatite
implant coating
zinc
Surfaces and Interfaces
Surfaces, Coatings and Films
Materials Chemistry
SDG 3 - Good Health and Well-being
title_short In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
title_full In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
title_fullStr In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
title_full_unstemmed In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
title_sort In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
author Pádua, Ana Sofia
author_facet Pádua, Ana Sofia
Gavinho, Sílvia Rodrigues
Vieira, Tânia
Hammami, Imen
Silva, Jorge Carvalho
Borges, João Paulo
Graça, Manuel Pedro Fernandes
author_role author
author2 Gavinho, Sílvia Rodrigues
Vieira, Tânia
Hammami, Imen
Silva, Jorge Carvalho
Borges, João Paulo
Graça, Manuel Pedro Fernandes
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
DF – Departamento de Física
RUN
dc.contributor.author.fl_str_mv Pádua, Ana Sofia
Gavinho, Sílvia Rodrigues
Vieira, Tânia
Hammami, Imen
Silva, Jorge Carvalho
Borges, João Paulo
Graça, Manuel Pedro Fernandes
dc.subject.por.fl_str_mv Bioglass 45S5
cerium
CoBlast
copper
hydroxyapatite
implant coating
zinc
Surfaces and Interfaces
Surfaces, Coatings and Films
Materials Chemistry
SDG 3 - Good Health and Well-being
topic Bioglass 45S5
cerium
CoBlast
copper
hydroxyapatite
implant coating
zinc
Surfaces and Interfaces
Surfaces, Coatings and Films
Materials Chemistry
SDG 3 - Good Health and Well-being
description Funding Information: FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985. Publisher Copyright: © 2023 by the authors.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-16
2023-10-16T00:00:00Z
2024-01-24T17:08:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/162722
url http://hdl.handle.net/10362/162722
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-6412
PURE: 82011332
https://doi.org/10.3390/coatings13101775
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 13
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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