Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia

Detalhes bibliográficos
Autor(a) principal: Donato, Mariana
Data de Publicação: 2018
Outros Autores: Pimentel, João, Cabral, Rui, Escada, Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802
Resumo: Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments.
id RCAP_5fb0357cad1a498cb1d81b9fd65ced90
oai_identifier_str oai:ojs.www.actamedicaportuguesa.com:article/8802
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic TelangiectasiaRadiofrequência no Tratamento da Epistaxis Refractária na Telangiectasia Hemorrágica HereditáriaEpistaxisRadiofrequencyTelangiectasiaHereditary HemorrhagicEpistaxeRadiofrequênciaTelangiectasia Hemorrágica HereditáriaHereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments.A telangiectasia hemorrágica hereditária é uma doença autossómica dominante, multissistémica e rara, caracterizada pela displasia do tecido conectivo vascular com tendência à hemorragia recorrente. O sintoma mais comum e precoce é a epistaxis. Habitualmente é ligeira a moderada, no entanto, em alguns doentes, pode ser severa com interferência significativa na sua qualidade de vida. É reportado o caso de um doente com telangiectasia hemorrágica hereditária, em que um episódio de epistaxis refractária foi tratado com radiofrequência e um quelante de fibrina. Com esta técnica foi conseguido não só o controlo da hemorragia activa, mas também a eliminação das telangiectasias. Após seis meses de seguimento, não houve recorrência da epistaxis. Há vários tratamentos descritos na literatura para a epistaxis nesta doença, não havendo no entanto, consenso acerca do gold standard. A ablação com radiofrequência das telangiectasias é uma técnica recente que se tem mostrado segura, eficaz e bem tolerada, mesmo em doentes submetidos previamente a outros tratamentos.Ordem dos Médicos2018-01-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802oai:ojs.www.actamedicaportuguesa.com:article/8802Acta Médica Portuguesa; Vol. 31 No. 1 (2018): January; 63-66Acta Médica Portuguesa; Vol. 31 N.º 1 (2018): Janeiro; 63-661646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802/5316Direitos de Autor (c) 2018 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessDonato, MarianaPimentel, JoãoCabral, RuiEscada, Pedro2022-12-20T11:05:38Zoai:ojs.www.actamedicaportuguesa.com:article/8802Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:38.769272Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
Radiofrequência no Tratamento da Epistaxis Refractária na Telangiectasia Hemorrágica Hereditária
title Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
spellingShingle Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
Donato, Mariana
Epistaxis
Radiofrequency
Telangiectasia
Hereditary Hemorrhagic
Epistaxe
Radiofrequência
Telangiectasia Hemorrágica Hereditária
title_short Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
title_full Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
title_fullStr Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
title_full_unstemmed Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
title_sort Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
author Donato, Mariana
author_facet Donato, Mariana
Pimentel, João
Cabral, Rui
Escada, Pedro
author_role author
author2 Pimentel, João
Cabral, Rui
Escada, Pedro
author2_role author
author
author
dc.contributor.author.fl_str_mv Donato, Mariana
Pimentel, João
Cabral, Rui
Escada, Pedro
dc.subject.por.fl_str_mv Epistaxis
Radiofrequency
Telangiectasia
Hereditary Hemorrhagic
Epistaxe
Radiofrequência
Telangiectasia Hemorrágica Hereditária
topic Epistaxis
Radiofrequency
Telangiectasia
Hereditary Hemorrhagic
Epistaxe
Radiofrequência
Telangiectasia Hemorrágica Hereditária
description Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-31
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802
oai:ojs.www.actamedicaportuguesa.com:article/8802
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/8802
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802/5316
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2018 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2018 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 31 No. 1 (2018): January; 63-66
Acta Médica Portuguesa; Vol. 31 N.º 1 (2018): Janeiro; 63-66
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799130646761701376