Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802 |
Resumo: | Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments. |
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Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic TelangiectasiaRadiofrequência no Tratamento da Epistaxis Refractária na Telangiectasia Hemorrágica HereditáriaEpistaxisRadiofrequencyTelangiectasiaHereditary HemorrhagicEpistaxeRadiofrequênciaTelangiectasia Hemorrágica HereditáriaHereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments.A telangiectasia hemorrágica hereditária é uma doença autossómica dominante, multissistémica e rara, caracterizada pela displasia do tecido conectivo vascular com tendência à hemorragia recorrente. O sintoma mais comum e precoce é a epistaxis. Habitualmente é ligeira a moderada, no entanto, em alguns doentes, pode ser severa com interferência significativa na sua qualidade de vida. É reportado o caso de um doente com telangiectasia hemorrágica hereditária, em que um episódio de epistaxis refractária foi tratado com radiofrequência e um quelante de fibrina. Com esta técnica foi conseguido não só o controlo da hemorragia activa, mas também a eliminação das telangiectasias. Após seis meses de seguimento, não houve recorrência da epistaxis. Há vários tratamentos descritos na literatura para a epistaxis nesta doença, não havendo no entanto, consenso acerca do gold standard. A ablação com radiofrequência das telangiectasias é uma técnica recente que se tem mostrado segura, eficaz e bem tolerada, mesmo em doentes submetidos previamente a outros tratamentos.Ordem dos Médicos2018-01-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802oai:ojs.www.actamedicaportuguesa.com:article/8802Acta Médica Portuguesa; Vol. 31 No. 1 (2018): January; 63-66Acta Médica Portuguesa; Vol. 31 N.º 1 (2018): Janeiro; 63-661646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802/5316Direitos de Autor (c) 2018 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessDonato, MarianaPimentel, JoãoCabral, RuiEscada, Pedro2022-12-20T11:05:38Zoai:ojs.www.actamedicaportuguesa.com:article/8802Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:38.769272Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia Radiofrequência no Tratamento da Epistaxis Refractária na Telangiectasia Hemorrágica Hereditária |
title |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
spellingShingle |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia Donato, Mariana Epistaxis Radiofrequency Telangiectasia Hereditary Hemorrhagic Epistaxe Radiofrequência Telangiectasia Hemorrágica Hereditária |
title_short |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
title_full |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
title_fullStr |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
title_full_unstemmed |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
title_sort |
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia |
author |
Donato, Mariana |
author_facet |
Donato, Mariana Pimentel, João Cabral, Rui Escada, Pedro |
author_role |
author |
author2 |
Pimentel, João Cabral, Rui Escada, Pedro |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Donato, Mariana Pimentel, João Cabral, Rui Escada, Pedro |
dc.subject.por.fl_str_mv |
Epistaxis Radiofrequency Telangiectasia Hereditary Hemorrhagic Epistaxe Radiofrequência Telangiectasia Hemorrágica Hereditária |
topic |
Epistaxis Radiofrequency Telangiectasia Hereditary Hemorrhagic Epistaxe Radiofrequência Telangiectasia Hemorrágica Hereditária |
description |
Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life. We report a case of a patient with hereditary hemorrhagic telangiectasia, in which an episode of refractory epistaxis was treated with radiofrequency and fibrin sealant. Control of acute bleeding and elimination of telangiectasia was possible with this technique. After six months follow-up, there was no epistaxis recurrence. Various treatments for epistaxis in this disease have been described in the literature, but there is no consensus about the gold-standard procedure. Radiofrequency ablation of telangiectasia is a recent technique that has shown to be safe, effective and well tolerated, even in patients who underwent other previous treatments. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-31 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802 oai:ojs.www.actamedicaportuguesa.com:article/8802 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/8802 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8802/5316 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2018 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2018 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 31 No. 1 (2018): January; 63-66 Acta Médica Portuguesa; Vol. 31 N.º 1 (2018): Janeiro; 63-66 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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