Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.4/2076 |
Resumo: | A subgroup of patients with gouty arthritis have a chronic recurring form that is particularly difficult to treat. Such patients experience repeated flares and often have abundant tophi. Many also have underlying comorbidities, such as renal impairment, cardiovascular disease, gastrointestinal disorders, obesity, and hypertension, which contraindicate the use of standard anti-inflammatory medications. Five patients with difficult to treat gouty arthritis who were either candidates and/or treated with anti-IL therapy are described. |
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Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World CasesArtrite GotosaSupressores da GotaInterleucina-1Selecção de DoentesA subgroup of patients with gouty arthritis have a chronic recurring form that is particularly difficult to treat. Such patients experience repeated flares and often have abundant tophi. Many also have underlying comorbidities, such as renal impairment, cardiovascular disease, gastrointestinal disorders, obesity, and hypertension, which contraindicate the use of standard anti-inflammatory medications. Five patients with difficult to treat gouty arthritis who were either candidates and/or treated with anti-IL therapy are described.RIHUCAvram, ADuarte, CSantos, MJPapagoras, CRitis, KScarpioni, RSchmidt, WSkendros, P2017-08-25T13:28:36Z2015-102015-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/2076engJoint Bone Spine. 2015 Oct;82 Suppl 1:eS17-29.10.1016/S1297-319X(15)30004-Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:23:23Zoai:rihuc.huc.min-saude.pt:10400.4/2076Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:04:32.889205Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
title |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
spellingShingle |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases Avram, A Artrite Gotosa Supressores da Gota Interleucina-1 Selecção de Doentes |
title_short |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
title_full |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
title_fullStr |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
title_full_unstemmed |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
title_sort |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases |
author |
Avram, A |
author_facet |
Avram, A Duarte, C Santos, MJ Papagoras, C Ritis, K Scarpioni, R Schmidt, W Skendros, P |
author_role |
author |
author2 |
Duarte, C Santos, MJ Papagoras, C Ritis, K Scarpioni, R Schmidt, W Skendros, P |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
RIHUC |
dc.contributor.author.fl_str_mv |
Avram, A Duarte, C Santos, MJ Papagoras, C Ritis, K Scarpioni, R Schmidt, W Skendros, P |
dc.subject.por.fl_str_mv |
Artrite Gotosa Supressores da Gota Interleucina-1 Selecção de Doentes |
topic |
Artrite Gotosa Supressores da Gota Interleucina-1 Selecção de Doentes |
description |
A subgroup of patients with gouty arthritis have a chronic recurring form that is particularly difficult to treat. Such patients experience repeated flares and often have abundant tophi. Many also have underlying comorbidities, such as renal impairment, cardiovascular disease, gastrointestinal disorders, obesity, and hypertension, which contraindicate the use of standard anti-inflammatory medications. Five patients with difficult to treat gouty arthritis who were either candidates and/or treated with anti-IL therapy are described. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-10 2015-10-01T00:00:00Z 2017-08-25T13:28:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.4/2076 |
url |
http://hdl.handle.net/10400.4/2076 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Joint Bone Spine. 2015 Oct;82 Suppl 1:eS17-29. 10.1016/S1297-319X(15)30004-X |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131707866087424 |