The antioxidant activity of prenylflavonoids

Detalhes bibliográficos
Autor(a) principal: Santos, Clementina M.M.
Data de Publicação: 2020
Outros Autores: Silva, Artur
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/25799
Resumo: Prenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored.
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spelling The antioxidant activity of prenylflavonoidsABTS assayChelation studiesDPPH radicalFlavonoidsFRAPLipid peroxidationNatural productsPrenylROSPrenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored.The authors are grateful to FCT/MEC, Fundação para a Ciência e Tecnologia and Ministério da Educação e Ciência, Portugal and FEDER, the Partnership Agreement PT2020, for financial support to CIMO (UID/AGR/00690/2019) and QOPNA (UID/QUI/00062/2019) as well as project POCI-01-0145-FEDER-016385. Acknowledgments: Thanks are due to University of Aveiro and Instituto Politécnico de Bragança for all support.MDPIBiblioteca Digital do IPBSantos, Clementina M.M.Silva, Artur2022-08-02T14:16:22Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/25799engSantos, Clementina M.M.; Silva, Artur (2020). The antioxidant activity of prenylflavonoids. Molecules. EISSN 1420-3049. 25:3, p. 1-3310.3390/molecules250306961420-3049info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:57:41Zoai:bibliotecadigital.ipb.pt:10198/25799Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:16:24.297643Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The antioxidant activity of prenylflavonoids
title The antioxidant activity of prenylflavonoids
spellingShingle The antioxidant activity of prenylflavonoids
Santos, Clementina M.M.
ABTS assay
Chelation studies
DPPH radical
Flavonoids
FRAP
Lipid peroxidation
Natural products
Prenyl
ROS
title_short The antioxidant activity of prenylflavonoids
title_full The antioxidant activity of prenylflavonoids
title_fullStr The antioxidant activity of prenylflavonoids
title_full_unstemmed The antioxidant activity of prenylflavonoids
title_sort The antioxidant activity of prenylflavonoids
author Santos, Clementina M.M.
author_facet Santos, Clementina M.M.
Silva, Artur
author_role author
author2 Silva, Artur
author2_role author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Santos, Clementina M.M.
Silva, Artur
dc.subject.por.fl_str_mv ABTS assay
Chelation studies
DPPH radical
Flavonoids
FRAP
Lipid peroxidation
Natural products
Prenyl
ROS
topic ABTS assay
Chelation studies
DPPH radical
Flavonoids
FRAP
Lipid peroxidation
Natural products
Prenyl
ROS
description Prenylated flavonoids combine the flavonoid moiety and the lipophilic prenyl side-chain. A great number of derivatives belonging to the class of chalcones, flavones, flavanones, isoflavones and other complex structures possessing di erent prenylation patterns have been studied in the past two decades for their potential as antioxidant agents. In this review, current knowledge on the natural occurrence and structural characteristics of both natural and synthetic derivatives was compiled. An exhaustive survey on the methods used to evaluate the antioxidant potential of these prenylflavonoids and the main results obtained were also presented and discussed. Whenever possible, structure-activity relationships were explored.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2022-08-02T14:16:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/25799
url http://hdl.handle.net/10198/25799
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Santos, Clementina M.M.; Silva, Artur (2020). The antioxidant activity of prenylflavonoids. Molecules. EISSN 1420-3049. 25:3, p. 1-33
10.3390/molecules25030696
1420-3049
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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