HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/7842 |
Resumo: | This article belongs to the Special Issue 2nd Edition: Human Biomonitoring of Environmental and Occupational Exposures |
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HBM4EU Occupational Biomonitoring Study on e-Waste-Study ProtocolBiomarkersEnvironmental GenotoxicityElectronic WasteOccupational ExposureHuman BiomonitoringCadmiumChromiumFlame RetardantsLeadMercuryPhthalatesRecyclingGenotoxicidade AmbientalThis article belongs to the Special Issue 2nd Edition: Human Biomonitoring of Environmental and Occupational ExposuresStudy ProtocolWorkers involved in the processing of electronic waste (e-waste) are potentially exposed to toxic chemicals. If exposure occurs, this may result in uptake and potential adverse health effects. Thus, exposure surveillance is an important requirement for health risk management and prevention of occupational disease. Human biomonitoring by measurement of specific biomarkers in body fluids is considered as an effective method of exposure surveillance. The aim of this study is to investigate the internal exposure of workers processing e-waste using a human biomonitoring approach, which will stimulate improved work practices and contribute to raising awareness of potential hazards. This exploratory study in occupational exposures in e-waste processing is part of the European Human Biomonitoring Initiative (HBM4EU). Here we present a study protocol using a cross sectional survey design to study worker's exposures and compare these to the exposure of subjects preferably employed in the same company but with no known exposure to industrial recycling of e-waste. The present study protocol will be applied in six to eight European countries to ensure standardised data collection. The target population size is 300 exposed and 150 controls. Biomarkers of exposure for the following chemicals will be used: chromium, cadmium and lead in blood and urine; brominated flame retardants and polychlorobiphenyls in blood; mercury, organophosphate flame retardants and phthalates in urine, and chromium, cadmium, lead and mercury in hair. In addition, the following effect biomarkers will be studied: micronuclei, epigenetic, oxidative stress, inflammatory markers and telomere length in blood and metabolomics in urine. Occupational hygiene sampling methods (airborne and settled dust, silicon wristbands and handwipes) and contextual information will be collected to facilitate the interpretation of the biomarker results and discuss exposure mitigating interventions to further reduce exposures if needed. This study protocol can be adapted to future European-wide occupational studies.This work has received external funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No. 733032 and received co-funding from the author’s organizations and/or Ministries.MDPIRepositório Científico do Instituto Nacional de SaúdeScheepers, Paul T.J.Duca, Radu CorneliuGalea, Karen S.Godderis, LodeHardy, EmilieKnudsen, Lisbeth E.Leese, ElizabethLouro, HenriquetaMahiout, SelmaNdaw, SophiePoels, KatrienPorras, Simo P.Silva, Maria JoãoTavares, Ana MariaVerdonck, JelleViegas, SusanaSantonen, TiinaHBM4EU e-Waste Study Team2022-01-10T16:03:10Z2021-12-092021-12-09T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/7842engInt J Environ Res Public Health. 2021 Dec 9;18(24):12987. doi: 10.3390/ijerph182412987.1660-460110.3390/ijerph182412987info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:18Zoai:repositorio.insa.pt:10400.18/7842Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:34.563164Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| title |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| spellingShingle |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol Scheepers, Paul T.J. Biomarkers Environmental Genotoxicity Electronic Waste Occupational Exposure Human Biomonitoring Cadmium Chromium Flame Retardants Lead Mercury Phthalates Recycling Genotoxicidade Ambiental |
| title_short |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| title_full |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| title_fullStr |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| title_full_unstemmed |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| title_sort |
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol |
| author |
Scheepers, Paul T.J. |
| author_facet |
Scheepers, Paul T.J. Duca, Radu Corneliu Galea, Karen S. Godderis, Lode Hardy, Emilie Knudsen, Lisbeth E. Leese, Elizabeth Louro, Henriqueta Mahiout, Selma Ndaw, Sophie Poels, Katrien Porras, Simo P. Silva, Maria João Tavares, Ana Maria Verdonck, Jelle Viegas, Susana Santonen, Tiina HBM4EU e-Waste Study Team |
| author_role |
author |
| author2 |
Duca, Radu Corneliu Galea, Karen S. Godderis, Lode Hardy, Emilie Knudsen, Lisbeth E. Leese, Elizabeth Louro, Henriqueta Mahiout, Selma Ndaw, Sophie Poels, Katrien Porras, Simo P. Silva, Maria João Tavares, Ana Maria Verdonck, Jelle Viegas, Susana Santonen, Tiina HBM4EU e-Waste Study Team |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Scheepers, Paul T.J. Duca, Radu Corneliu Galea, Karen S. Godderis, Lode Hardy, Emilie Knudsen, Lisbeth E. Leese, Elizabeth Louro, Henriqueta Mahiout, Selma Ndaw, Sophie Poels, Katrien Porras, Simo P. Silva, Maria João Tavares, Ana Maria Verdonck, Jelle Viegas, Susana Santonen, Tiina HBM4EU e-Waste Study Team |
| dc.subject.por.fl_str_mv |
Biomarkers Environmental Genotoxicity Electronic Waste Occupational Exposure Human Biomonitoring Cadmium Chromium Flame Retardants Lead Mercury Phthalates Recycling Genotoxicidade Ambiental |
| topic |
Biomarkers Environmental Genotoxicity Electronic Waste Occupational Exposure Human Biomonitoring Cadmium Chromium Flame Retardants Lead Mercury Phthalates Recycling Genotoxicidade Ambiental |
| description |
This article belongs to the Special Issue 2nd Edition: Human Biomonitoring of Environmental and Occupational Exposures |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-12-09 2021-12-09T00:00:00Z 2022-01-10T16:03:10Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/7842 |
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http://hdl.handle.net/10400.18/7842 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Int J Environ Res Public Health. 2021 Dec 9;18(24):12987. doi: 10.3390/ijerph182412987. 1660-4601 10.3390/ijerph182412987 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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MDPI |
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MDPI |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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