Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.74.4.681 |
Resumo: | Graham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area. |
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Graham-Little-Piccardi-Lasseur Syndrome: Report of a CaseSíndrome de Graham-Little-Piccardi-Lasseur: Relato de Um CasoAlopeciaLichen PlanusHypotrichosisSyndromeAlopeciaLiquen PlanoHipotricoseSíndromeGraham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area.A Síndrome de Graham-Little-Piccardi-Lasseur (SGLPL), variante folicular do Liquen Plano, caracteriza-se por apresentar, progressivamente: alopecia cicatricial multifocal do couro cabeludo associada a queratose folicular disseminada e hipotricose não cicatricial axilar e púbica. Os achados clínicos da síndrome podem estar presentes simultaneamente, embora a alopecia do couro cabeludo muitas vezes preceda os outros achados em meses a anos. Atinge principalmente mulheres na idade adulta, sendo considerada uma doença rara. A terapêutica desta dermatose é um desafio, apresentando resultados controversos. Relatamos o caso de uma paciente do sexo feminino, 75 anos, apresentando área de alopecia na região parietal direita, pápulas violáceas poligonais pruriginosas paravertebrais, máculas hipercrômicas com rendilhado branco na mucosa oral além de discreta diminuição dos pelos axilares. Após uso de hidroxizina associada à aplicação de propionato de clobetasol tópico e betametasona intralesional na placa alopécica observamos discreta melhoria.Sociedade Portuguesa de Dermatologia e Venereologia2016-12-26T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.74.4.681oai:ojs.revista.spdv.com.pt:article/681Journal of the Portuguese Society of Dermatology and Venereology; Vol 74 No 4 (2016): Outubro - Dezembro; 397-400Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 74 n. 4 (2016): Outubro - Dezembro; 397-4002182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/681https://doi.org/10.29021/spdv.74.4.681https://revista.spdv.com.pt/index.php/spdv/article/view/681/465Martins Nóbrega, MonisaMarques Feitosa Mendes Siqueira, ThaisSantiago Ormay, MarianaLago Obadi, DanielGripp, Alexandre Carlosinfo:eu-repo/semantics/openAccess2022-10-06T12:35:01Zoai:ojs.revista.spdv.com.pt:article/681Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:00.183018Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case Síndrome de Graham-Little-Piccardi-Lasseur: Relato de Um Caso |
title |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
spellingShingle |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case Martins Nóbrega, Monisa Alopecia Lichen Planus Hypotrichosis Syndrome Alopecia Liquen Plano Hipotricose Síndrome |
title_short |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
title_full |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
title_fullStr |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
title_full_unstemmed |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
title_sort |
Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case |
author |
Martins Nóbrega, Monisa |
author_facet |
Martins Nóbrega, Monisa Marques Feitosa Mendes Siqueira, Thais Santiago Ormay, Mariana Lago Obadi, Daniel Gripp, Alexandre Carlos |
author_role |
author |
author2 |
Marques Feitosa Mendes Siqueira, Thais Santiago Ormay, Mariana Lago Obadi, Daniel Gripp, Alexandre Carlos |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Martins Nóbrega, Monisa Marques Feitosa Mendes Siqueira, Thais Santiago Ormay, Mariana Lago Obadi, Daniel Gripp, Alexandre Carlos |
dc.subject.por.fl_str_mv |
Alopecia Lichen Planus Hypotrichosis Syndrome Alopecia Liquen Plano Hipotricose Síndrome |
topic |
Alopecia Lichen Planus Hypotrichosis Syndrome Alopecia Liquen Plano Hipotricose Síndrome |
description |
Graham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-12-26T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.74.4.681 oai:ojs.revista.spdv.com.pt:article/681 |
url |
https://doi.org/10.29021/spdv.74.4.681 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/681 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/681 https://doi.org/10.29021/spdv.74.4.681 https://revista.spdv.com.pt/index.php/spdv/article/view/681/465 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 74 No 4 (2016): Outubro - Dezembro; 397-400 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 74 n. 4 (2016): Outubro - Dezembro; 397-400 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130565958434816 |