Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case

Detalhes bibliográficos
Autor(a) principal: Martins Nóbrega, Monisa
Data de Publicação: 2016
Outros Autores: Marques Feitosa Mendes Siqueira, Thais, Santiago Ormay, Mariana, Lago Obadi, Daniel, Gripp, Alexandre Carlos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.74.4.681
Resumo: Graham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area.
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spelling Graham-Little-Piccardi-Lasseur Syndrome: Report of a CaseSíndrome de Graham-Little-Piccardi-Lasseur: Relato de Um CasoAlopeciaLichen PlanusHypotrichosisSyndromeAlopeciaLiquen PlanoHipotricoseSíndromeGraham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area.A Síndrome de Graham-Little-Piccardi-Lasseur (SGLPL), variante folicular do Liquen Plano, caracteriza-se por apresentar, progressivamente: alopecia cicatricial multifocal do couro cabeludo associada a queratose folicular disseminada e hipotricose não cicatricial axilar e púbica. Os achados clínicos da síndrome podem estar presentes simultaneamente, embora a alopecia do couro cabeludo muitas vezes preceda os outros achados em meses a anos. Atinge principalmente mulheres na idade adulta, sendo considerada uma doença rara. A terapêutica desta dermatose é um desafio, apresentando resultados controversos. Relatamos o caso de uma paciente do sexo feminino, 75 anos, apresentando área de alopecia na região parietal direita, pápulas violáceas poligonais pruriginosas paravertebrais, máculas hipercrômicas com rendilhado branco na mucosa oral além de discreta diminuição dos pelos axilares. Após uso de hidroxizina associada à aplicação de propionato de clobetasol tópico e betametasona intralesional na placa alopécica observamos discreta melhoria.Sociedade Portuguesa de Dermatologia e Venereologia2016-12-26T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.74.4.681oai:ojs.revista.spdv.com.pt:article/681Journal of the Portuguese Society of Dermatology and Venereology; Vol 74 No 4 (2016): Outubro - Dezembro; 397-400Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 74 n. 4 (2016): Outubro - Dezembro; 397-4002182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/681https://doi.org/10.29021/spdv.74.4.681https://revista.spdv.com.pt/index.php/spdv/article/view/681/465Martins Nóbrega, MonisaMarques Feitosa Mendes Siqueira, ThaisSantiago Ormay, MarianaLago Obadi, DanielGripp, Alexandre Carlosinfo:eu-repo/semantics/openAccess2022-10-06T12:35:01Zoai:ojs.revista.spdv.com.pt:article/681Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:00.183018Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
Síndrome de Graham-Little-Piccardi-Lasseur: Relato de Um Caso
title Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
spellingShingle Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
Martins Nóbrega, Monisa
Alopecia
Lichen Planus
Hypotrichosis
Syndrome
Alopecia
Liquen Plano
Hipotricose
Síndrome
title_short Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
title_full Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
title_fullStr Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
title_full_unstemmed Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
title_sort Graham-Little-Piccardi-Lasseur Syndrome: Report of a Case
author Martins Nóbrega, Monisa
author_facet Martins Nóbrega, Monisa
Marques Feitosa Mendes Siqueira, Thais
Santiago Ormay, Mariana
Lago Obadi, Daniel
Gripp, Alexandre Carlos
author_role author
author2 Marques Feitosa Mendes Siqueira, Thais
Santiago Ormay, Mariana
Lago Obadi, Daniel
Gripp, Alexandre Carlos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Martins Nóbrega, Monisa
Marques Feitosa Mendes Siqueira, Thais
Santiago Ormay, Mariana
Lago Obadi, Daniel
Gripp, Alexandre Carlos
dc.subject.por.fl_str_mv Alopecia
Lichen Planus
Hypotrichosis
Syndrome
Alopecia
Liquen Plano
Hipotricose
Síndrome
topic Alopecia
Lichen Planus
Hypotrichosis
Syndrome
Alopecia
Liquen Plano
Hipotricose
Síndrome
description Graham-Little-Piccardi-Lasseur Syndrome (SGLPL) is characterized by a progressive multifocal scarring alopecia of the scalp associated with disseminated follicular hyperkeratosis and non-scarring axillary and pubic hypotrichosis. These clinical aspects may occur simultaneously, although alopecia of the scalp often precedes the other findings in months to years. It affects mainly adult females and is considered a rare disease. Treatment is challenging with many suggested medications but with controversial results. We report the case of a female patient with an area of alopecia in the right parietal region, paravertebral violaceous pruritic polygonal papules, hyperchromic macules with white reticular lesions on the oral mucosa as well as a slight hypotrichosis of the axillae. A slight improvement was observed after oral hidroxizine associated with topical clobetasol propionate and intralesional betamethasone in the limits of the alopecic area.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-26T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.74.4.681
oai:ojs.revista.spdv.com.pt:article/681
url https://doi.org/10.29021/spdv.74.4.681
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/681
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/681
https://doi.org/10.29021/spdv.74.4.681
https://revista.spdv.com.pt/index.php/spdv/article/view/681/465
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 74 No 4 (2016): Outubro - Dezembro; 397-400
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 74 n. 4 (2016): Outubro - Dezembro; 397-400
2182-2409
2182-2395
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