Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering

Detalhes bibliográficos
Autor(a) principal: Pereira, Susana R
Data de Publicação: 2015
Outros Autores: Sanchez i Nogue, Violeta, Frazao, Cludio J R, Serafim, Luisa S, Gorwa-Grauslund, Marie F, Xavier, Ana M R B
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/18152
Resumo: Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol.
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spelling Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineeringHardwood spent sulfite liquor (HSSL)Scheffersomyces stipitisLignocellulosic inhibitorsEvolutionary engineeringBioethanolHardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol.Biomes Central2017-07-28T11:38:48Z2015-01-01T00:00:00Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/18152eng1754-683410.1186/s13068-015-0234-yPereira, Susana RSanchez i Nogue, VioletaFrazao, Cludio J RSerafim, Luisa SGorwa-Grauslund, Marie FXavier, Ana M R Binfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:33:34Zoai:ria.ua.pt:10773/18152Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:52:39.111277Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
title Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
spellingShingle Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
Pereira, Susana R
Hardwood spent sulfite liquor (HSSL)
Scheffersomyces stipitis
Lignocellulosic inhibitors
Evolutionary engineering
Bioethanol
title_short Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
title_full Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
title_fullStr Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
title_full_unstemmed Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
title_sort Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
author Pereira, Susana R
author_facet Pereira, Susana R
Sanchez i Nogue, Violeta
Frazao, Cludio J R
Serafim, Luisa S
Gorwa-Grauslund, Marie F
Xavier, Ana M R B
author_role author
author2 Sanchez i Nogue, Violeta
Frazao, Cludio J R
Serafim, Luisa S
Gorwa-Grauslund, Marie F
Xavier, Ana M R B
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Susana R
Sanchez i Nogue, Violeta
Frazao, Cludio J R
Serafim, Luisa S
Gorwa-Grauslund, Marie F
Xavier, Ana M R B
dc.subject.por.fl_str_mv Hardwood spent sulfite liquor (HSSL)
Scheffersomyces stipitis
Lignocellulosic inhibitors
Evolutionary engineering
Bioethanol
topic Hardwood spent sulfite liquor (HSSL)
Scheffersomyces stipitis
Lignocellulosic inhibitors
Evolutionary engineering
Bioethanol
description Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01T00:00:00Z
2015
2017-07-28T11:38:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/18152
url http://hdl.handle.net/10773/18152
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1754-6834
10.1186/s13068-015-0234-y
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Biomes Central
publisher.none.fl_str_mv Biomes Central
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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