Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/18152 |
Resumo: | Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol. |
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Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineeringHardwood spent sulfite liquor (HSSL)Scheffersomyces stipitisLignocellulosic inhibitorsEvolutionary engineeringBioethanolHardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol.Biomes Central2017-07-28T11:38:48Z2015-01-01T00:00:00Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/18152eng1754-683410.1186/s13068-015-0234-yPereira, Susana RSanchez i Nogue, VioletaFrazao, Cludio J RSerafim, Luisa SGorwa-Grauslund, Marie FXavier, Ana M R Binfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:33:34Zoai:ria.ua.pt:10773/18152Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:52:39.111277Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
title |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
spellingShingle |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering Pereira, Susana R Hardwood spent sulfite liquor (HSSL) Scheffersomyces stipitis Lignocellulosic inhibitors Evolutionary engineering Bioethanol |
title_short |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
title_full |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
title_fullStr |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
title_full_unstemmed |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
title_sort |
Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
author |
Pereira, Susana R |
author_facet |
Pereira, Susana R Sanchez i Nogue, Violeta Frazao, Cludio J R Serafim, Luisa S Gorwa-Grauslund, Marie F Xavier, Ana M R B |
author_role |
author |
author2 |
Sanchez i Nogue, Violeta Frazao, Cludio J R Serafim, Luisa S Gorwa-Grauslund, Marie F Xavier, Ana M R B |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pereira, Susana R Sanchez i Nogue, Violeta Frazao, Cludio J R Serafim, Luisa S Gorwa-Grauslund, Marie F Xavier, Ana M R B |
dc.subject.por.fl_str_mv |
Hardwood spent sulfite liquor (HSSL) Scheffersomyces stipitis Lignocellulosic inhibitors Evolutionary engineering Bioethanol |
topic |
Hardwood spent sulfite liquor (HSSL) Scheffersomyces stipitis Lignocellulosic inhibitors Evolutionary engineering Bioethanol |
description |
Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-01-01T00:00:00Z 2015 2017-07-28T11:38:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/18152 |
url |
http://hdl.handle.net/10773/18152 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1754-6834 10.1186/s13068-015-0234-y |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Biomes Central |
publisher.none.fl_str_mv |
Biomes Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137577301704704 |