Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function

Detalhes bibliográficos
Autor(a) principal: Bosio, Morgana
Data de Publicação: 2018
Outros Autores: Souza, Bianca, Saggioro, Enrico, Dezotti, Marcia, Bassin, João Paulo, Quinta-Ferreira, Emilia, Quinta-Ferreira, Rosa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/101886
https://doi.org/10.1016/j.egypro.2018.10.012
Resumo: Thousands of compounds are used and disposed of every day and many of them are not degraded in conventional treatment plants. It is necessary an alternative to eliminate these compounds. This can be done through electrooxidation technology, which was applied in this work to a mixture of pharmaceutical compounds including alprazolam (ALP), clonazepam (CLP), diazepam (DZP), lorazepam (LZP) and carbamazepine (CBZ) at 100 µg.L-1. The mixture was studied with different types of electrolytes and the neurotoxic effect of the treatment was evaluated. The best result was obtained with NaCl (0.5 g.L-1), leading to complete degradation of CLP, LZP and CBZ.
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spelling Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic functionBenzodiazepinesElectrooxidationHippocampalNeurotoxicityThousands of compounds are used and disposed of every day and many of them are not degraded in conventional treatment plants. It is necessary an alternative to eliminate these compounds. This can be done through electrooxidation technology, which was applied in this work to a mixture of pharmaceutical compounds including alprazolam (ALP), clonazepam (CLP), diazepam (DZP), lorazepam (LZP) and carbamazepine (CBZ) at 100 µg.L-1. The mixture was studied with different types of electrolytes and the neurotoxic effect of the treatment was evaluated. The best result was obtained with NaCl (0.5 g.L-1), leading to complete degradation of CLP, LZP and CBZ.2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/101886http://hdl.handle.net/10316/101886https://doi.org/10.1016/j.egypro.2018.10.012eng18766102Bosio, MorganaSouza, BiancaSaggioro, EnricoDezotti, MarciaBassin, João PauloQuinta-Ferreira, EmiliaQuinta-Ferreira, Rosainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T21:45:49Zoai:estudogeral.uc.pt:10316/101886Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:18:59.054500Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
title Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
spellingShingle Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
Bosio, Morgana
Benzodiazepines
Electrooxidation
Hippocampal
Neurotoxicity
title_short Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
title_full Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
title_fullStr Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
title_full_unstemmed Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
title_sort Pharmaceutical compounds electrotreatment by Pt anodes and effect on synaptic function
author Bosio, Morgana
author_facet Bosio, Morgana
Souza, Bianca
Saggioro, Enrico
Dezotti, Marcia
Bassin, João Paulo
Quinta-Ferreira, Emilia
Quinta-Ferreira, Rosa
author_role author
author2 Souza, Bianca
Saggioro, Enrico
Dezotti, Marcia
Bassin, João Paulo
Quinta-Ferreira, Emilia
Quinta-Ferreira, Rosa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bosio, Morgana
Souza, Bianca
Saggioro, Enrico
Dezotti, Marcia
Bassin, João Paulo
Quinta-Ferreira, Emilia
Quinta-Ferreira, Rosa
dc.subject.por.fl_str_mv Benzodiazepines
Electrooxidation
Hippocampal
Neurotoxicity
topic Benzodiazepines
Electrooxidation
Hippocampal
Neurotoxicity
description Thousands of compounds are used and disposed of every day and many of them are not degraded in conventional treatment plants. It is necessary an alternative to eliminate these compounds. This can be done through electrooxidation technology, which was applied in this work to a mixture of pharmaceutical compounds including alprazolam (ALP), clonazepam (CLP), diazepam (DZP), lorazepam (LZP) and carbamazepine (CBZ) at 100 µg.L-1. The mixture was studied with different types of electrolytes and the neurotoxic effect of the treatment was evaluated. The best result was obtained with NaCl (0.5 g.L-1), leading to complete degradation of CLP, LZP and CBZ.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/101886
http://hdl.handle.net/10316/101886
https://doi.org/10.1016/j.egypro.2018.10.012
url http://hdl.handle.net/10316/101886
https://doi.org/10.1016/j.egypro.2018.10.012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 18766102
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