Warfarin hipersensitivity: how to deal with it?.

Detalhes bibliográficos
Autor(a) principal: Lima, Ana Furtado
Data de Publicação: 2010
Outros Autores: Reis, José, Serrano, Fátima, Borges, Augusta
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678
Resumo: The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.
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spelling Warfarin hipersensitivity: how to deal with it?.Hipersensibilidade à varfarina: que abordagem?The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.Ordem dos Médicos2010-07-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678oai:ojs.www.actamedicaportuguesa.com:article/678Acta Médica Portuguesa; Vol. 23 No. 4 (2010): July-August; 727-30Acta Médica Portuguesa; Vol. 23 N.º 4 (2010): Julho-Agosto; 727-301646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678/356Lima, Ana FurtadoReis, JoséSerrano, FátimaBorges, Augustainfo:eu-repo/semantics/openAccess2022-12-20T10:56:40Zoai:ojs.www.actamedicaportuguesa.com:article/678Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:40.350078Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Warfarin hipersensitivity: how to deal with it?.
Hipersensibilidade à varfarina: que abordagem?
title Warfarin hipersensitivity: how to deal with it?.
spellingShingle Warfarin hipersensitivity: how to deal with it?.
Lima, Ana Furtado
title_short Warfarin hipersensitivity: how to deal with it?.
title_full Warfarin hipersensitivity: how to deal with it?.
title_fullStr Warfarin hipersensitivity: how to deal with it?.
title_full_unstemmed Warfarin hipersensitivity: how to deal with it?.
title_sort Warfarin hipersensitivity: how to deal with it?.
author Lima, Ana Furtado
author_facet Lima, Ana Furtado
Reis, José
Serrano, Fátima
Borges, Augusta
author_role author
author2 Reis, José
Serrano, Fátima
Borges, Augusta
author2_role author
author
author
dc.contributor.author.fl_str_mv Lima, Ana Furtado
Reis, José
Serrano, Fátima
Borges, Augusta
description The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.
publishDate 2010
dc.date.none.fl_str_mv 2010-07-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678
oai:ojs.www.actamedicaportuguesa.com:article/678
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/678
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678/356
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 23 No. 4 (2010): July-August; 727-30
Acta Médica Portuguesa; Vol. 23 N.º 4 (2010): Julho-Agosto; 727-30
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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