Warfarin hipersensitivity: how to deal with it?.
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678 |
Resumo: | The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin. |
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Warfarin hipersensitivity: how to deal with it?.Hipersensibilidade à varfarina: que abordagem?The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.Ordem dos Médicos2010-07-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678oai:ojs.www.actamedicaportuguesa.com:article/678Acta Médica Portuguesa; Vol. 23 No. 4 (2010): July-August; 727-30Acta Médica Portuguesa; Vol. 23 N.º 4 (2010): Julho-Agosto; 727-301646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678/356Lima, Ana FurtadoReis, JoséSerrano, FátimaBorges, Augustainfo:eu-repo/semantics/openAccess2022-12-20T10:56:40Zoai:ojs.www.actamedicaportuguesa.com:article/678Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:40.350078Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Warfarin hipersensitivity: how to deal with it?. Hipersensibilidade à varfarina: que abordagem? |
title |
Warfarin hipersensitivity: how to deal with it?. |
spellingShingle |
Warfarin hipersensitivity: how to deal with it?. Lima, Ana Furtado |
title_short |
Warfarin hipersensitivity: how to deal with it?. |
title_full |
Warfarin hipersensitivity: how to deal with it?. |
title_fullStr |
Warfarin hipersensitivity: how to deal with it?. |
title_full_unstemmed |
Warfarin hipersensitivity: how to deal with it?. |
title_sort |
Warfarin hipersensitivity: how to deal with it?. |
author |
Lima, Ana Furtado |
author_facet |
Lima, Ana Furtado Reis, José Serrano, Fátima Borges, Augusta |
author_role |
author |
author2 |
Reis, José Serrano, Fátima Borges, Augusta |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Lima, Ana Furtado Reis, José Serrano, Fátima Borges, Augusta |
description |
The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-07-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678 oai:ojs.www.actamedicaportuguesa.com:article/678 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/678 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/678/356 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 23 No. 4 (2010): July-August; 727-30 Acta Médica Portuguesa; Vol. 23 N.º 4 (2010): Julho-Agosto; 727-30 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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