Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents

Detalhes bibliográficos
Autor(a) principal: Domingues, Joana
Data de Publicação: 2023
Outros Autores: Goulão, M.F., Delgado, F.M.G., Gonçalves, J.C., Gonçalves, Joana, Pintado, C.S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.11/8455
Resumo: Chemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability) in NHDF cells at all concentrations tested.
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spelling Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agentsL. stoechas subsp. luisieriL. pedunculataChemical profileAntimicrobial activityCytotoxicityChemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability) in NHDF cells at all concentrations tested.MDPIRepositório Científico do Instituto Politécnico de Castelo BrancoDomingues, JoanaGoulão, M.F.Delgado, F.M.G.Gonçalves, J.C.Gonçalves, JoanaPintado, C.S.2023-04-18T12:05:12Z20232023-04-11T15:09:27Z2023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.11/8455engDOMINGUES, Joana [et al.] (2023) - Essential oils of two Portuguese endemic species of lavandula as a source of antifungal and antibacterial sgents. Processes. 11, 1165. DOI https:// doi.org/10.3390/pr11041165cv-prod-323084610.3390/pr11041165info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-04-22T01:47:05Zoai:repositorio.ipcb.pt:10400.11/8455Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:50:01.306207Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
title Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
spellingShingle Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
Domingues, Joana
L. stoechas subsp. luisieri
L. pedunculata
Chemical profile
Antimicrobial activity
Cytotoxicity
title_short Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
title_full Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
title_fullStr Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
title_full_unstemmed Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
title_sort Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
author Domingues, Joana
author_facet Domingues, Joana
Goulão, M.F.
Delgado, F.M.G.
Gonçalves, J.C.
Gonçalves, Joana
Pintado, C.S.
author_role author
author2 Goulão, M.F.
Delgado, F.M.G.
Gonçalves, J.C.
Gonçalves, Joana
Pintado, C.S.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico de Castelo Branco
dc.contributor.author.fl_str_mv Domingues, Joana
Goulão, M.F.
Delgado, F.M.G.
Gonçalves, J.C.
Gonçalves, Joana
Pintado, C.S.
dc.subject.por.fl_str_mv L. stoechas subsp. luisieri
L. pedunculata
Chemical profile
Antimicrobial activity
Cytotoxicity
topic L. stoechas subsp. luisieri
L. pedunculata
Chemical profile
Antimicrobial activity
Cytotoxicity
description Chemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability) in NHDF cells at all concentrations tested.
publishDate 2023
dc.date.none.fl_str_mv 2023-04-18T12:05:12Z
2023
2023-04-11T15:09:27Z
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.11/8455
url http://hdl.handle.net/10400.11/8455
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv DOMINGUES, Joana [et al.] (2023) - Essential oils of two Portuguese endemic species of lavandula as a source of antifungal and antibacterial sgents. Processes. 11, 1165. DOI https:// doi.org/10.3390/pr11041165
cv-prod-3230846
10.3390/pr11041165
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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