The mechanism of the Legionella VipA protein in altering actin dynamics during infection

Detalhes bibliográficos
Autor(a) principal: Carvalho, Ana Teresa Carrilho
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/120872
Resumo: Dissertation presented to obtain the Master Degree in Biochemistry for Health
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spelling The mechanism of the Legionella VipA protein in altering actin dynamics during infectionLegionella pneumophilabacterial effector;VipAactinnucleatorendocytic pathwayDissertation presented to obtain the Master Degree in Biochemistry for Health"Legionella pneumophila is a facultative intracellular bacterium that is commonly found in fresh water and soils, parasitizing a wide range of protozoa hosts. Co-evolution mechanisms allowed this bacterium to parasitize other phagocytic cells and rendered it the ability to become a potential human pathogen. For instance, after inhalation of contaminated aerosols by the host, it can survive and replicate inside human macrophages in the lungs by creating a specialized phagosome that is not degraded, possibly resulting in the severe pneumonia known as Legionnaires’ disease. L. pneumophila relies on a type IV secretion system to inject effector proteins into the host cell to disrupt or take advantage of several cellular processes.(...)"Universidade Nova de Lisboa, Instituto de Tecnologiaa Química e Biológica António XavierRUNCarvalho, Ana Teresa Carrilho2021-07-11T23:58:04Z2019-102019-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/120872enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:03:17Zoai:run.unl.pt:10362/120872Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:27.502054Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The mechanism of the Legionella VipA protein in altering actin dynamics during infection
title The mechanism of the Legionella VipA protein in altering actin dynamics during infection
spellingShingle The mechanism of the Legionella VipA protein in altering actin dynamics during infection
Carvalho, Ana Teresa Carrilho
Legionella pneumophila
bacterial effector;
VipA
actin
nucleator
endocytic pathway
title_short The mechanism of the Legionella VipA protein in altering actin dynamics during infection
title_full The mechanism of the Legionella VipA protein in altering actin dynamics during infection
title_fullStr The mechanism of the Legionella VipA protein in altering actin dynamics during infection
title_full_unstemmed The mechanism of the Legionella VipA protein in altering actin dynamics during infection
title_sort The mechanism of the Legionella VipA protein in altering actin dynamics during infection
author Carvalho, Ana Teresa Carrilho
author_facet Carvalho, Ana Teresa Carrilho
author_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Carvalho, Ana Teresa Carrilho
dc.subject.por.fl_str_mv Legionella pneumophila
bacterial effector;
VipA
actin
nucleator
endocytic pathway
topic Legionella pneumophila
bacterial effector;
VipA
actin
nucleator
endocytic pathway
description Dissertation presented to obtain the Master Degree in Biochemistry for Health
publishDate 2019
dc.date.none.fl_str_mv 2019-10
2019-10-01T00:00:00Z
2021-07-11T23:58:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/120872
url http://hdl.handle.net/10362/120872
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nova de Lisboa, Instituto de Tecnologiaa Química e Biológica António Xavier
publisher.none.fl_str_mv Universidade Nova de Lisboa, Instituto de Tecnologiaa Química e Biológica António Xavier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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