Early identification of individuals at risk for loss to follow-up of tuberculosis treatment

Detalhes bibliográficos
Autor(a) principal: Lima, Shirley Verônica Melo Almeida
Data de Publicação: 2021
Outros Autores: de Araújo, Karina Conceição Gomes Machado, Nunes, Marco Antonio Prado, Nunes, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/121732
Resumo: Funding Information: This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior , Brazil, ID: 88881.187327/2018–01 . Publisher Copyright: © 2021 The Author(s) Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
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spelling Early identification of individuals at risk for loss to follow-up of tuberculosis treatmenta generalised hierarchical analysisEpidemiologyRisk factorsSocial determinants of healthTherapyTuberculosisGeneralSDG 3 - Good Health and Well-beingSDG 10 - Reduced InequalitiesFunding Information: This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior , Brazil, ID: 88881.187327/2018–01 . Publisher Copyright: © 2021 The Author(s) Copyright: Copyright 2021 Elsevier B.V., All rights reserved.Background: We characterise the loss to follow-up (locally termed abandoned) of tuberculosis treatment with individual and ecological health determinants and to identify the predictive capacity of these risk factors. Methods: A cohort study with individual and ecological characterisation of patients diagnosed with tuberculosis in Sergipe/Brazil from 2015 to 2018 with either loss to follow-up or completion of treatment as a therapeutic outcome was performed. The examined variables were based on the social determinants of health with descriptive analysis, binary logistic regression, a generalised hierarchical model and graphical presentation using a nomogram. Results: The loss to follow-up accounted for 18.21% of the 2,449 studied cases. The characteristics revealed that the highest abandonment percentages were people who: were male (20.0%), had black skin colour (20.3%), were aged 20–39 years (21.8%), had 4–7 years of schooling (23.6%), re-entered treatment after abandonment (36.5%), used alcohol (31.0%), used drugs (39.3%), were smokers (26.5%) and were homeless (55.4%). The ecological characteristics showed that individuals living in municipalities with a high human development index (HDI; odds ratio [OR]: 1.91) and high-income inequality (OR: 1.81) had a greater chance of not finishing the treatment. Most of these variables were identified as predictors in the generalised hierarchical model; the receiver operating characteristic curve (ROC) curve had 0.771 precision and 84.0% accuracy. Conclusion: The group of identified characteristics influenced the loss to follow-up of tuberculosis treatment. This data provides evidence for the early identification of individuals who are at greater risk of abandoning tuberculosis treatment.Escola Nacional de Saúde Pública (ENSP)Centro de Investigação em Saúde Pública (CISP/PHRC)RUNLima, Shirley Verônica Melo Almeidade Araújo, Karina Conceição Gomes MachadoNunes, Marco Antonio PradoNunes, Carla2021-07-27T22:22:23Z2021-042021-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/121732eng2405-8440PURE: 32838342https://doi.org/10.1016/j.heliyon.2021.e06788info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:03:53Zoai:run.unl.pt:10362/121732Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:42.722620Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
a generalised hierarchical analysis
title Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
spellingShingle Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
Lima, Shirley Verônica Melo Almeida
Epidemiology
Risk factors
Social determinants of health
Therapy
Tuberculosis
General
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
title_short Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
title_full Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
title_fullStr Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
title_full_unstemmed Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
title_sort Early identification of individuals at risk for loss to follow-up of tuberculosis treatment
author Lima, Shirley Verônica Melo Almeida
author_facet Lima, Shirley Verônica Melo Almeida
de Araújo, Karina Conceição Gomes Machado
Nunes, Marco Antonio Prado
Nunes, Carla
author_role author
author2 de Araújo, Karina Conceição Gomes Machado
Nunes, Marco Antonio Prado
Nunes, Carla
author2_role author
author
author
dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Lima, Shirley Verônica Melo Almeida
de Araújo, Karina Conceição Gomes Machado
Nunes, Marco Antonio Prado
Nunes, Carla
dc.subject.por.fl_str_mv Epidemiology
Risk factors
Social determinants of health
Therapy
Tuberculosis
General
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
topic Epidemiology
Risk factors
Social determinants of health
Therapy
Tuberculosis
General
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
description Funding Information: This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior , Brazil, ID: 88881.187327/2018–01 . Publisher Copyright: © 2021 The Author(s) Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-27T22:22:23Z
2021-04
2021-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/121732
url http://hdl.handle.net/10362/121732
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2405-8440
PURE: 32838342
https://doi.org/10.1016/j.heliyon.2021.e06788
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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