Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants

Detalhes bibliográficos
Autor(a) principal: Talebian, Sepehr
Data de Publicação: 2023
Outros Autores: Mendes, Bárbara, Conniot, João, Farajikhah, Syamak, Dehghani, Fariba, Li, Zhongyan, Bitoque, Diogo, Silva, Gabriela, Naficy, Sina, Conde, João, Wallace, Gordon G.
Tipo de documento: Outros
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/149674
Resumo: Funding Information: S.T., B.M., and J.C. contributed equally to this work. The authors are grateful for funding received from the Australian Research Council Centre of Excellence program (Project Number CE 140100012). J.C. acknowledges the European Research Council Starting Grant (ERC‐StG‐2019‐848325). S.N. and F.D. acknowledge the financial support of Australian Research Council through DP200102164. Publisher Copyright: © 2023 The Authors. Advanced Science published by Wiley-VCH GmbH.
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spelling Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implantsbiopolymerscontrolled releasedrug deliverymedical ImplantsMedicine (miscellaneous)Chemical Engineering(all)Materials Science(all)Biochemistry, Genetics and Molecular Biology (miscellaneous)Engineering(all)Physics and Astronomy(all)Funding Information: S.T., B.M., and J.C. contributed equally to this work. The authors are grateful for funding received from the Australian Research Council Centre of Excellence program (Project Number CE 140100012). J.C. acknowledges the European Research Council Starting Grant (ERC‐StG‐2019‐848325). S.N. and F.D. acknowledge the financial support of Australian Research Council through DP200102164. Publisher Copyright: © 2023 The Authors. Advanced Science published by Wiley-VCH GmbH.The deployment of structures that enable localized release of bioactive molecules can result in more efficacious treatment of disease and better integration of implantable bionic devices. The strategic design of a biopolymeric coating can be used to engineer the optimal release profile depending on the task at hand. As illustrative examples, here advances in delivery of drugs from bone, brain, ocular, and cardiovascular implants are reviewed. These areas are focused to highlight that both hard and soft tissue implants can benefit from controlled localized delivery. The composition of biopolymers used to achieve appropriate delivery to the selected tissue types, and their corresponding outcomes are brought to the fore. To conclude, key factors in designing drug-loaded biopolymeric coatings for biomedical implants are highlighted.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centre for Toxicogenomics and Human Health (ToxOmics)RUNTalebian, SepehrMendes, BárbaraConniot, JoãoFarajikhah, SyamakDehghani, FaribaLi, ZhongyanBitoque, DiogoSilva, GabrielaNaficy, SinaConde, JoãoWallace, Gordon G.2023-02-24T22:26:54Z2023-04-262023-04-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/149674eng2198-3844PURE: 54218902https://doi.org/10.1002/advs.202207603info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:09:29Zoai:run.unl.pt:10362/149674Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:09:29Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
title Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
spellingShingle Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
Talebian, Sepehr
biopolymers
controlled release
drug delivery
medical Implants
Medicine (miscellaneous)
Chemical Engineering(all)
Materials Science(all)
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Engineering(all)
Physics and Astronomy(all)
title_short Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
title_full Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
title_fullStr Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
title_full_unstemmed Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
title_sort Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants
author Talebian, Sepehr
author_facet Talebian, Sepehr
Mendes, Bárbara
Conniot, João
Farajikhah, Syamak
Dehghani, Fariba
Li, Zhongyan
Bitoque, Diogo
Silva, Gabriela
Naficy, Sina
Conde, João
Wallace, Gordon G.
author_role author
author2 Mendes, Bárbara
Conniot, João
Farajikhah, Syamak
Dehghani, Fariba
Li, Zhongyan
Bitoque, Diogo
Silva, Gabriela
Naficy, Sina
Conde, João
Wallace, Gordon G.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Centre for Toxicogenomics and Human Health (ToxOmics)
RUN
dc.contributor.author.fl_str_mv Talebian, Sepehr
Mendes, Bárbara
Conniot, João
Farajikhah, Syamak
Dehghani, Fariba
Li, Zhongyan
Bitoque, Diogo
Silva, Gabriela
Naficy, Sina
Conde, João
Wallace, Gordon G.
dc.subject.por.fl_str_mv biopolymers
controlled release
drug delivery
medical Implants
Medicine (miscellaneous)
Chemical Engineering(all)
Materials Science(all)
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Engineering(all)
Physics and Astronomy(all)
topic biopolymers
controlled release
drug delivery
medical Implants
Medicine (miscellaneous)
Chemical Engineering(all)
Materials Science(all)
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Engineering(all)
Physics and Astronomy(all)
description Funding Information: S.T., B.M., and J.C. contributed equally to this work. The authors are grateful for funding received from the Australian Research Council Centre of Excellence program (Project Number CE 140100012). J.C. acknowledges the European Research Council Starting Grant (ERC‐StG‐2019‐848325). S.N. and F.D. acknowledge the financial support of Australian Research Council through DP200102164. Publisher Copyright: © 2023 The Authors. Advanced Science published by Wiley-VCH GmbH.
publishDate 2023
dc.date.none.fl_str_mv 2023-02-24T22:26:54Z
2023-04-26
2023-04-26T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/149674
url http://hdl.handle.net/10362/149674
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2198-3844
PURE: 54218902
https://doi.org/10.1002/advs.202207603
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
_version_ 1817545918442897408

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