Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal

Detalhes bibliográficos
Autor(a) principal: Costa, Miguel Mendes
Data de Publicação: 2022
Outros Autores: Cardo, Miguel, Soares, Patricia, D’anjo, Maria Cara, Leite, Andreia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/137174
Resumo: Funding Information: Funding: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Fundação para a Ciência e Tecnologia (PD/BD/135759/2018). Funding Information: The present publication was funded by Funda??o Ci?ncia e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Funda??o para a Ci?ncia e Tecnologia (PD/BD/135759/2018). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in PortugalFood safetyFood-producing animalsMulti-drug resistanceSurveillanceZoonotic bacteriaMicrobiologyBiochemistryPharmacology, Toxicology and Pharmaceutics(all)Microbiology (medical)Infectious DiseasesPharmacology (medical)SDG 3 - Good Health and Well-beingFunding Information: Funding: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Fundação para a Ciência e Tecnologia (PD/BD/135759/2018). Funding Information: The present publication was funded by Funda??o Ci?ncia e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Funda??o para a Ci?ncia e Tecnologia (PD/BD/135759/2018). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Animal and food sources are seen as a potential transmission pathway of antimicrobial resistance (AMR) to humans. The aim of this study is to describe Campylobacter, Salmonella, and commensal Escherichia coli multi-drug resistance (MDR) in the food chain between 2014 and 2019 in Portugal. AMR surveillance data from food-producing animals and food were assessed. MDR relative frequencies were estimated by bacterial genus and year. AMR profiles were created using ob-servations of resistance to antimicrobial classes from each isolate. Antimicrobial susceptibility testing results were clustered using k-modes. Clusters were described by population, AMR classification, β-lactamases, sample stage, sample type, season, and year. Overall, MDR was more prevalent for E. coli, ranging from 74–90% in animal and 94–100% in food samples. MDR was found to be more widespread in resistance profiles that were common among E. coli and Salmonella isolates and in those exclusively observed for E. coli, frequently including (fluoro)quinolones and cephalosporins resistance. β-lactam resistance was observed around 75% to 3rd/4th-generation cephalosporins in E. coli. Clusters suggest an escalating MDR behaviour from farm to post-farm stages in all bacteria and that Salmonella (fluoro)quinolones resistance may be associated with broilers. These findings support policy and decision making to tackle MDR in farm and post-farm stages.Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)Escola Nacional de Saúde Pública (ENSP)RUNCosta, Miguel MendesCardo, MiguelSoares, PatriciaD’anjo, Maria CaraLeite, Andreia2022-04-29T22:35:47Z2022-012022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/137174eng2079-6382PURE: 43565339https://doi.org/10.3390/antibiotics11010090info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:50Zoai:run.unl.pt:10362/137174Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:48.718353Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
title Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
spellingShingle Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
Costa, Miguel Mendes
Food safety
Food-producing animals
Multi-drug resistance
Surveillance
Zoonotic bacteria
Microbiology
Biochemistry
Pharmacology, Toxicology and Pharmaceutics(all)
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)
SDG 3 - Good Health and Well-being
title_short Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
title_full Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
title_fullStr Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
title_full_unstemmed Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
title_sort Multi-Drug and β-Lactam resistance in Escherichia Coli and Food-Borne Pathogens from animals and food in Portugal
author Costa, Miguel Mendes
author_facet Costa, Miguel Mendes
Cardo, Miguel
Soares, Patricia
D’anjo, Maria Cara
Leite, Andreia
author_role author
author2 Cardo, Miguel
Soares, Patricia
D’anjo, Maria Cara
Leite, Andreia
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
Escola Nacional de Saúde Pública (ENSP)
RUN
dc.contributor.author.fl_str_mv Costa, Miguel Mendes
Cardo, Miguel
Soares, Patricia
D’anjo, Maria Cara
Leite, Andreia
dc.subject.por.fl_str_mv Food safety
Food-producing animals
Multi-drug resistance
Surveillance
Zoonotic bacteria
Microbiology
Biochemistry
Pharmacology, Toxicology and Pharmaceutics(all)
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)
SDG 3 - Good Health and Well-being
topic Food safety
Food-producing animals
Multi-drug resistance
Surveillance
Zoonotic bacteria
Microbiology
Biochemistry
Pharmacology, Toxicology and Pharmaceutics(all)
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)
SDG 3 - Good Health and Well-being
description Funding Information: Funding: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Fundação para a Ciência e Tecnologia (PD/BD/135759/2018). Funding Information: The present publication was funded by Funda??o Ci?ncia e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Costa, M.M. was funded by Funda??o para a Ci?ncia e Tecnologia (PD/BD/135759/2018). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-29T22:35:47Z
2022-01
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/137174
url http://hdl.handle.net/10362/137174
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-6382
PURE: 43565339
https://doi.org/10.3390/antibiotics11010090
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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