Introduction to hCOMET special issue, ‘Comet assay in vitro’

Detalhes bibliográficos
Autor(a) principal: Dusinska, Maria
Data de Publicação: 2019
Outros Autores: Costa, Solange, Collins, Andrew
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/6625
Resumo: Editorial
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spelling Introduction to hCOMET special issue, ‘Comet assay in vitro’AnimalsBiological MonitoringCell LineComet AssayHumansLaboratory Proficiency TestingReproducibility of ResultsEditorialThis special issue is produced as a valuable outcome of the COST Action hCOMET. A major aim of this project is to encourage the adoption of standard procedures for the comet assay, in order to improve reliability. Comet assay procedures tend to vary from one laboratory to another, and so comparing results between laboratories can be problematic. Much work has been done to establish how different parameters, such as agarose concentration, lysis time, or electrophoresis voltage gradient can affect results, and an aspiration of hCOMET is to devise standard procedures. In addition to papers on practical issues relating to the use of the comet assay, there are several descriptions of novel model cell systems. Finally, there are accounts of various applications of the assay to in vitro genotoxicity testing (mainly on human cell lines), as well as investigations of antigenotoxicity. (...)ElsevierRepositório Científico do Instituto Nacional de SaúdeDusinska, MariaCosta, SolangeCollins, Andrew2020-05-08T19:02:21Z2019-07-032019-07-03T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/6625engMutat Res. 2019 Sep;845:403071. doi: 10.1016/j.mrgentox.2019.07.001. Epub 2019 Jul 30027-510710.1016/j.mrgentox.2019.07.001info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:46Zoai:repositorio.insa.pt:10400.18/6625Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:42.737180Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Introduction to hCOMET special issue, ‘Comet assay in vitro’
title Introduction to hCOMET special issue, ‘Comet assay in vitro’
spellingShingle Introduction to hCOMET special issue, ‘Comet assay in vitro’
Dusinska, Maria
Animals
Biological Monitoring
Cell Line
Comet Assay
Humans
Laboratory Proficiency Testing
Reproducibility of Results
title_short Introduction to hCOMET special issue, ‘Comet assay in vitro’
title_full Introduction to hCOMET special issue, ‘Comet assay in vitro’
title_fullStr Introduction to hCOMET special issue, ‘Comet assay in vitro’
title_full_unstemmed Introduction to hCOMET special issue, ‘Comet assay in vitro’
title_sort Introduction to hCOMET special issue, ‘Comet assay in vitro’
author Dusinska, Maria
author_facet Dusinska, Maria
Costa, Solange
Collins, Andrew
author_role author
author2 Costa, Solange
Collins, Andrew
author2_role author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Dusinska, Maria
Costa, Solange
Collins, Andrew
dc.subject.por.fl_str_mv Animals
Biological Monitoring
Cell Line
Comet Assay
Humans
Laboratory Proficiency Testing
Reproducibility of Results
topic Animals
Biological Monitoring
Cell Line
Comet Assay
Humans
Laboratory Proficiency Testing
Reproducibility of Results
description Editorial
publishDate 2019
dc.date.none.fl_str_mv 2019-07-03
2019-07-03T00:00:00Z
2020-05-08T19:02:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/6625
url http://hdl.handle.net/10400.18/6625
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Mutat Res. 2019 Sep;845:403071. doi: 10.1016/j.mrgentox.2019.07.001. Epub 2019 Jul 3
0027-5107
10.1016/j.mrgentox.2019.07.001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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