Deconstructing the molecular mechanisms shaping the vertebrate body plan

Detalhes bibliográficos
Autor(a) principal: Aires, Rita
Data de Publicação: 2018
Outros Autores: Dias, André, Mallo, Moisés
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/907
Resumo: The large display of body shapes and sizes observed among vertebrates ultimately represent variations of a common basic body plan. This likely results from the use of homologous developmental schemes, just differentially tinkered both in amplitude and timing by natural selection. In this review, we will revisit, discuss and combine old ideas with new concepts to update our view on how the vertebrate body is built. Recent advances, particularly at the molecular level, will guide our deconstruction of the individual developmental modules that sequentially produce head, neck, trunk and tail structures, and the transitions between them.
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spelling Deconstructing the molecular mechanisms shaping the vertebrate body planAnimalsBiological EvolutionBody PatterningMesodermModels, BiologicalPrimitive StreakVertebratesThe large display of body shapes and sizes observed among vertebrates ultimately represent variations of a common basic body plan. This likely results from the use of homologous developmental schemes, just differentially tinkered both in amplitude and timing by natural selection. In this review, we will revisit, discuss and combine old ideas with new concepts to update our view on how the vertebrate body is built. Recent advances, particularly at the molecular level, will guide our deconstruction of the individual developmental modules that sequentially produce head, neck, trunk and tail structures, and the transitions between them.ARCAAires, RitaDias, AndréMallo, Moisés2019-08-29T10:49:51Z20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/907eng10.1016/j.ceb.2018.05.009info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:19Zoai:arca.igc.gulbenkian.pt:10400.7/907Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:12:06.733866Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Deconstructing the molecular mechanisms shaping the vertebrate body plan
title Deconstructing the molecular mechanisms shaping the vertebrate body plan
spellingShingle Deconstructing the molecular mechanisms shaping the vertebrate body plan
Aires, Rita
Animals
Biological Evolution
Body Patterning
Mesoderm
Models, Biological
Primitive Streak
Vertebrates
title_short Deconstructing the molecular mechanisms shaping the vertebrate body plan
title_full Deconstructing the molecular mechanisms shaping the vertebrate body plan
title_fullStr Deconstructing the molecular mechanisms shaping the vertebrate body plan
title_full_unstemmed Deconstructing the molecular mechanisms shaping the vertebrate body plan
title_sort Deconstructing the molecular mechanisms shaping the vertebrate body plan
author Aires, Rita
author_facet Aires, Rita
Dias, André
Mallo, Moisés
author_role author
author2 Dias, André
Mallo, Moisés
author2_role author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Aires, Rita
Dias, André
Mallo, Moisés
dc.subject.por.fl_str_mv Animals
Biological Evolution
Body Patterning
Mesoderm
Models, Biological
Primitive Streak
Vertebrates
topic Animals
Biological Evolution
Body Patterning
Mesoderm
Models, Biological
Primitive Streak
Vertebrates
description The large display of body shapes and sizes observed among vertebrates ultimately represent variations of a common basic body plan. This likely results from the use of homologous developmental schemes, just differentially tinkered both in amplitude and timing by natural selection. In this review, we will revisit, discuss and combine old ideas with new concepts to update our view on how the vertebrate body is built. Recent advances, particularly at the molecular level, will guide our deconstruction of the individual developmental modules that sequentially produce head, neck, trunk and tail structures, and the transitions between them.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01T00:00:00Z
2019-08-29T10:49:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/907
url http://hdl.handle.net/10400.7/907
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.ceb.2018.05.009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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