Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency

Detalhes bibliográficos
Autor(a) principal: Sousa, Liliana B.
Data de Publicação: 2020
Outros Autores: Santos-Costa, Paulo, Marques, Inês A., Cruz, Arménio, Salgueiro-Oliveira, Anabela, Parreira, Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.14/31833
Resumo: This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.
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spelling Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiencyDouble-chamber syringesVascular access devicesFlushingPatent reviewThis review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.MDPIVeritati - Repositório Institucional da Universidade Católica PortuguesaSousa, Liliana B.Santos-Costa, PauloMarques, Inês A.Cruz, ArménioSalgueiro-Oliveira, AnabelaParreira, Pedro2021-02-01T18:40:26Z2020-11-012020-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/31833engSousa, L. B., Santos-Costa, P., Marques, I. A., Cruz, A., Salgueiro-Oliveira, A., Parreira, P. (2020). Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency. International Journal of Environmental Research and Public Health, 17(21), 82091660-460110.3390/ijerph1721820985095606858PMC766441633172109000588992700001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-10T01:40:11Zoai:repositorio.ucp.pt:10400.14/31833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:25:42.212885Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
title Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
spellingShingle Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
Sousa, Liliana B.
Double-chamber syringes
Vascular access devices
Flushing
Patent review
title_short Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
title_full Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
title_fullStr Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
title_full_unstemmed Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
title_sort Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
author Sousa, Liliana B.
author_facet Sousa, Liliana B.
Santos-Costa, Paulo
Marques, Inês A.
Cruz, Arménio
Salgueiro-Oliveira, Anabela
Parreira, Pedro
author_role author
author2 Santos-Costa, Paulo
Marques, Inês A.
Cruz, Arménio
Salgueiro-Oliveira, Anabela
Parreira, Pedro
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Veritati - Repositório Institucional da Universidade Católica Portuguesa
dc.contributor.author.fl_str_mv Sousa, Liliana B.
Santos-Costa, Paulo
Marques, Inês A.
Cruz, Arménio
Salgueiro-Oliveira, Anabela
Parreira, Pedro
dc.subject.por.fl_str_mv Double-chamber syringes
Vascular access devices
Flushing
Patent review
topic Double-chamber syringes
Vascular access devices
Flushing
Patent review
description This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-01
2020-11-01T00:00:00Z
2021-02-01T18:40:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.14/31833
url http://hdl.handle.net/10400.14/31833
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sousa, L. B., Santos-Costa, P., Marques, I. A., Cruz, A., Salgueiro-Oliveira, A., Parreira, P. (2020). Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency. International Journal of Environmental Research and Public Health, 17(21), 8209
1660-4601
10.3390/ijerph17218209
85095606858
PMC7664416
33172109
000588992700001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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