Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.14/31833 |
Resumo: | This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush. |
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Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiencyDouble-chamber syringesVascular access devicesFlushingPatent reviewThis review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.MDPIVeritati - Repositório Institucional da Universidade Católica PortuguesaSousa, Liliana B.Santos-Costa, PauloMarques, Inês A.Cruz, ArménioSalgueiro-Oliveira, AnabelaParreira, Pedro2021-02-01T18:40:26Z2020-11-012020-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/31833engSousa, L. B., Santos-Costa, P., Marques, I. A., Cruz, A., Salgueiro-Oliveira, A., Parreira, P. (2020). Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency. International Journal of Environmental Research and Public Health, 17(21), 82091660-460110.3390/ijerph1721820985095606858PMC766441633172109000588992700001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-10T01:40:11Zoai:repositorio.ucp.pt:10400.14/31833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:25:42.212885Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
title |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
spellingShingle |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency Sousa, Liliana B. Double-chamber syringes Vascular access devices Flushing Patent review |
title_short |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
title_full |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
title_fullStr |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
title_full_unstemmed |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
title_sort |
Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency |
author |
Sousa, Liliana B. |
author_facet |
Sousa, Liliana B. Santos-Costa, Paulo Marques, Inês A. Cruz, Arménio Salgueiro-Oliveira, Anabela Parreira, Pedro |
author_role |
author |
author2 |
Santos-Costa, Paulo Marques, Inês A. Cruz, Arménio Salgueiro-Oliveira, Anabela Parreira, Pedro |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Veritati - Repositório Institucional da Universidade Católica Portuguesa |
dc.contributor.author.fl_str_mv |
Sousa, Liliana B. Santos-Costa, Paulo Marques, Inês A. Cruz, Arménio Salgueiro-Oliveira, Anabela Parreira, Pedro |
dc.subject.por.fl_str_mv |
Double-chamber syringes Vascular access devices Flushing Patent review |
topic |
Double-chamber syringes Vascular access devices Flushing Patent review |
description |
This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-11-01 2020-11-01T00:00:00Z 2021-02-01T18:40:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.14/31833 |
url |
http://hdl.handle.net/10400.14/31833 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Sousa, L. B., Santos-Costa, P., Marques, I. A., Cruz, A., Salgueiro-Oliveira, A., Parreira, P. (2020). Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency. International Journal of Environmental Research and Public Health, 17(21), 8209 1660-4601 10.3390/ijerph17218209 85095606858 PMC7664416 33172109 000588992700001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
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MDPI |
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MDPI |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131972580147200 |