FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence

Detalhes bibliográficos
Autor(a) principal: Simões, Catarina D.
Data de Publicação: 2022
Outros Autores: Maganinho, Marta, Sousa, Ana S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10284/10632
Resumo: Purpose Based on the fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) hypothesis, the low-FODMAP diet has been suggested as a potential therapeutic approach for inflammatory bowel disease (IBD) with promising results on disease management. However, this diet implies a specific broad food restriction, which potentially increases the risk of nutritional deficiencies and may aggravate gut microbiota dysbiosis of IBD patients. The aim of the present study is to review the effect of individual FODMAPs on the human gut microbiota. In addition, this narrative review provides an updated overview of the use of the low-FODMAP diet in IBD, namely the implementation, advantages, limitations, and the impact on the gut microbiota. Methods The literature search strategy was applied to PubMed and Web of Science using relevant keywords, IBD, FODMAPs, Fructose, Lactose, Polyols, FOS, GOS, low-FODMAP diet and gut microbiota. Results Current data suggest that the low-FODMAP diet may effectively improve clinical outcomes in the management of IBD and ensure better quality of life for IBD patients. However, there is evidence highlighting some issues of concern, particularly the adequacy of the diet and the impact on the gut microbiota. The various FODMAP types differently modulate the gut microbiota. Conclusion IBD management should be achieved with the least possible dietary restriction to avoid detrimental consequences, particularly on nutritional adequacy and gut microbiota. Thus, it is important to individualize and monitor the nutrition intervention. Further studies are required to better characterize the relationship between diet, the gut microbiota, and IBD to support the generalization of this approach for clinical practice in IBD therapy and management.
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spelling FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidenceFODMAPsMicrobiotaInflammatory bowel diseasesLow-FODMAP dietDiet therapyPurpose Based on the fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) hypothesis, the low-FODMAP diet has been suggested as a potential therapeutic approach for inflammatory bowel disease (IBD) with promising results on disease management. However, this diet implies a specific broad food restriction, which potentially increases the risk of nutritional deficiencies and may aggravate gut microbiota dysbiosis of IBD patients. The aim of the present study is to review the effect of individual FODMAPs on the human gut microbiota. In addition, this narrative review provides an updated overview of the use of the low-FODMAP diet in IBD, namely the implementation, advantages, limitations, and the impact on the gut microbiota. Methods The literature search strategy was applied to PubMed and Web of Science using relevant keywords, IBD, FODMAPs, Fructose, Lactose, Polyols, FOS, GOS, low-FODMAP diet and gut microbiota. Results Current data suggest that the low-FODMAP diet may effectively improve clinical outcomes in the management of IBD and ensure better quality of life for IBD patients. However, there is evidence highlighting some issues of concern, particularly the adequacy of the diet and the impact on the gut microbiota. The various FODMAP types differently modulate the gut microbiota. Conclusion IBD management should be achieved with the least possible dietary restriction to avoid detrimental consequences, particularly on nutritional adequacy and gut microbiota. Thus, it is important to individualize and monitor the nutrition intervention. Further studies are required to better characterize the relationship between diet, the gut microbiota, and IBD to support the generalization of this approach for clinical practice in IBD therapy and management.SpringerRepositório Institucional da Universidade Fernando PessoaSimões, Catarina D.Maganinho, MartaSousa, Ana S.2022-01-13T12:50:07Z2022-01-06T00:00:00Z2022-01-06T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10284/10632engSimões, C.D., Maganinho, M. & Sousa, A.S. FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence. Eur J Nutr (2022). https://doi.org/10.1007/s00394-021-02755-11436-6207https://doi.org/10.1007/s00394-021-02755-1metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-06T02:09:54Zoai:bdigital.ufp.pt:10284/10632Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:47:24.282339Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
title FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
spellingShingle FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
Simões, Catarina D.
FODMAPs
Microbiota
Inflammatory bowel diseases
Low-FODMAP diet
Diet therapy
title_short FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
title_full FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
title_fullStr FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
title_full_unstemmed FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
title_sort FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence
author Simões, Catarina D.
author_facet Simões, Catarina D.
Maganinho, Marta
Sousa, Ana S.
author_role author
author2 Maganinho, Marta
Sousa, Ana S.
author2_role author
author
dc.contributor.none.fl_str_mv Repositório Institucional da Universidade Fernando Pessoa
dc.contributor.author.fl_str_mv Simões, Catarina D.
Maganinho, Marta
Sousa, Ana S.
dc.subject.por.fl_str_mv FODMAPs
Microbiota
Inflammatory bowel diseases
Low-FODMAP diet
Diet therapy
topic FODMAPs
Microbiota
Inflammatory bowel diseases
Low-FODMAP diet
Diet therapy
description Purpose Based on the fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) hypothesis, the low-FODMAP diet has been suggested as a potential therapeutic approach for inflammatory bowel disease (IBD) with promising results on disease management. However, this diet implies a specific broad food restriction, which potentially increases the risk of nutritional deficiencies and may aggravate gut microbiota dysbiosis of IBD patients. The aim of the present study is to review the effect of individual FODMAPs on the human gut microbiota. In addition, this narrative review provides an updated overview of the use of the low-FODMAP diet in IBD, namely the implementation, advantages, limitations, and the impact on the gut microbiota. Methods The literature search strategy was applied to PubMed and Web of Science using relevant keywords, IBD, FODMAPs, Fructose, Lactose, Polyols, FOS, GOS, low-FODMAP diet and gut microbiota. Results Current data suggest that the low-FODMAP diet may effectively improve clinical outcomes in the management of IBD and ensure better quality of life for IBD patients. However, there is evidence highlighting some issues of concern, particularly the adequacy of the diet and the impact on the gut microbiota. The various FODMAP types differently modulate the gut microbiota. Conclusion IBD management should be achieved with the least possible dietary restriction to avoid detrimental consequences, particularly on nutritional adequacy and gut microbiota. Thus, it is important to individualize and monitor the nutrition intervention. Further studies are required to better characterize the relationship between diet, the gut microbiota, and IBD to support the generalization of this approach for clinical practice in IBD therapy and management.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-13T12:50:07Z
2022-01-06T00:00:00Z
2022-01-06T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10284/10632
url http://hdl.handle.net/10284/10632
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Simões, C.D., Maganinho, M. & Sousa, A.S. FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence. Eur J Nutr (2022). https://doi.org/10.1007/s00394-021-02755-1
1436-6207
https://doi.org/10.1007/s00394-021-02755-1
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dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
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instacron:RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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