Tuberculous lymphadenitis: Proposal of a protocol

• Autor(a) principal: Branco Lopes, Mariana
• Data de Publicação: 2022
• Outros Autores: Ferreira, Filipa, Santos, Cláudia, André, Carla, Antunes, Luís
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.34631/sporl.1025
• topic: Tuberculose ganglionar; diagnóstico atempado; PCR; Polimerase chain reaction; Mycobacterium tuberculosis; Tuberculous lymphadenitis; Early Diagnosis; PCR; Polimerase chain reaction; Mycobacterium tuberculosis

Introduction: Tuberculous lymphadenitis (TL) is one of the most common forms of extrapulmonary tuberculosis. It’s also the most frequent manifestation in head and neck region. Objectives: Present cases of cervical TL diagnosed in ENT department of Hospital Garcia de Orta. Propose of a protocol of diagnostic investigation, with focus on excisional biopsy to get material to histological, cultural, and molecular study. Material and Methods: Retrospective study. Descriptive analysis of cases of TL diagnosed in ENT department of Hospital Garcia de Orta with consultation of clinical records. Results and Conclusions: This study analyzed 7 cases diagnosed with cervical TL. The patients were mostly female and immunocompetent. The definitive diagnosis was only possible after excisional biopsy of an adenopathy and its histological, cultural and molecular (nucleic acid amplification test PCR) examination. In most cases, the diagnose was only possible with combination of histological and molecular results. The authors propose that in suspected cases, after exclusion of malignancy with CAAF, it should be performed a excisional biopsy with histological, cultural and molecular analyses. This form of actuation will enhance the probability of a correct and prompt diagnosis.