Tuberculous lymphadenitis: Proposal of a protocol
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.34631/sporl.1025 |
Resumo: | Introduction: Tuberculous lymphadenitis (TL) is one of the most common forms of extrapulmonary tuberculosis. It’s also the most frequent manifestation in head and neck region. Objectives: Present cases of cervical TL diagnosed in ENT department of Hospital Garcia de Orta. Propose of a protocol of diagnostic investigation, with focus on excisional biopsy to get material to histological, cultural, and molecular study. Material and Methods: Retrospective study. Descriptive analysis of cases of TL diagnosed in ENT department of Hospital Garcia de Orta with consultation of clinical records. Results and Conclusions: This study analyzed 7 cases diagnosed with cervical TL. The patients were mostly female and immunocompetent. The definitive diagnosis was only possible after excisional biopsy of an adenopathy and its histological, cultural and molecular (nucleic acid amplification test PCR) examination. In most cases, the diagnose was only possible with combination of histological and molecular results. The authors propose that in suspected cases, after exclusion of malignancy with CAAF, it should be performed a excisional biopsy with histological, cultural and molecular analyses. This form of actuation will enhance the probability of a correct and prompt diagnosis. |
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Tuberculous lymphadenitis: Proposal of a protocolTurberculose ganglionar: Proposta de protocolo de atuaçãoTuberculose ganglionardiagnóstico atempadoPCRPolimerase chain reactionMycobacterium tuberculosisTuberculous lymphadenitisEarly DiagnosisPCRPolimerase chain reactionMycobacterium tuberculosisIntroduction: Tuberculous lymphadenitis (TL) is one of the most common forms of extrapulmonary tuberculosis. It’s also the most frequent manifestation in head and neck region. Objectives: Present cases of cervical TL diagnosed in ENT department of Hospital Garcia de Orta. Propose of a protocol of diagnostic investigation, with focus on excisional biopsy to get material to histological, cultural, and molecular study. Material and Methods: Retrospective study. Descriptive analysis of cases of TL diagnosed in ENT department of Hospital Garcia de Orta with consultation of clinical records. Results and Conclusions: This study analyzed 7 cases diagnosed with cervical TL. The patients were mostly female and immunocompetent. The definitive diagnosis was only possible after excisional biopsy of an adenopathy and its histological, cultural and molecular (nucleic acid amplification test PCR) examination. In most cases, the diagnose was only possible with combination of histological and molecular results. The authors propose that in suspected cases, after exclusion of malignancy with CAAF, it should be performed a excisional biopsy with histological, cultural and molecular analyses. This form of actuation will enhance the probability of a correct and prompt diagnosis.Introdução: A tuberculose ganglionar (TG) é uma das formas de apresentação mais frequente de tuberculose extrapulmonar, sendo também a mais comum na área de cabeça e pescoço. Objetivos: Apresentar casos de TG cervical diagnosticados no Serviço de Otorrinolaringologia do Hospital Garcia de Orta, analisando as dificuldades no diagnóstico através de citologia aspirativa com agulha fina. Proposta de protocolo de atuação com obtenção de amostra através de biópsia excisional, para posterior análise histológica, cultural e molecular. Material e Métodos: Estudo retrospetivo. Análise descritiva dos casos de TG cervical diagnosticados no Serviço de Otorrinolaringologia do Hospital Garcia de Orta com consulta dos processos clínicos. Resultados e Conclusões: Foram analisados 7 casos diagnosticados com TG cervical. Os doentes eram, na sua maioria, do sexo feminino e imunocompetentes. Para esclarecimento do diagnóstico definitivo foi necessária, em todos os casos, a realização de biópsia excisional de gânglio cervical com estudo histológico, cultural e molecular (pesquisa de ADN de micobactérias por PCR) da amostra. Na maioria dos casos a definição do diagnóstico definitivo só foi possível com a combinação dos resultados histológicos e moleculares. Os autores propõem que em casos suspeitos de TG cervical, após exclusão de malignidade por CAAF, seja realizada biópsia excisional com estudo histológico, cultural e molecular. Esta forma de atuação, aumentará, assim, a probabilidade de um diagnóstico correto e atempado.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2022-12-18info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.34631/sporl.1025https://doi.org/10.34631/sporl.1025Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 60 No. 4 (2022): December; 295-300Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 60 Núm. 4 (2022): Dezembro; 295-300Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 60 N.º 4 (2022): Dezembro; 295-3002184-6499reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://journalsporl.com/index.php/sporl/article/view/2105https://journalsporl.com/index.php/sporl/article/view/2105/105https://journalsporl.com/index.php/sporl/article/view/2105/106Direitos de Autor (c) 2022 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoçoinfo:eu-repo/semantics/openAccessBranco Lopes, MarianaFerreira, FilipaSantos, CláudiaAndré, CarlaAntunes, Luís2024-01-04T12:51:24Zoai:journalsporl.com:article/2105Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:29:59.975837Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Tuberculous lymphadenitis: Proposal of a protocol Turberculose ganglionar: Proposta de protocolo de atuação |
title |
Tuberculous lymphadenitis: Proposal of a protocol |
spellingShingle |
Tuberculous lymphadenitis: Proposal of a protocol Branco Lopes, Mariana Tuberculose ganglionar diagnóstico atempado PCR Polimerase chain reaction Mycobacterium tuberculosis Tuberculous lymphadenitis Early Diagnosis PCR Polimerase chain reaction Mycobacterium tuberculosis |
title_short |
Tuberculous lymphadenitis: Proposal of a protocol |
title_full |
Tuberculous lymphadenitis: Proposal of a protocol |
title_fullStr |
Tuberculous lymphadenitis: Proposal of a protocol |
title_full_unstemmed |
Tuberculous lymphadenitis: Proposal of a protocol |
title_sort |
Tuberculous lymphadenitis: Proposal of a protocol |
author |
Branco Lopes, Mariana |
author_facet |
Branco Lopes, Mariana Ferreira, Filipa Santos, Cláudia André, Carla Antunes, Luís |
author_role |
author |
author2 |
Ferreira, Filipa Santos, Cláudia André, Carla Antunes, Luís |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Branco Lopes, Mariana Ferreira, Filipa Santos, Cláudia André, Carla Antunes, Luís |
dc.subject.por.fl_str_mv |
Tuberculose ganglionar diagnóstico atempado PCR Polimerase chain reaction Mycobacterium tuberculosis Tuberculous lymphadenitis Early Diagnosis PCR Polimerase chain reaction Mycobacterium tuberculosis |
topic |
Tuberculose ganglionar diagnóstico atempado PCR Polimerase chain reaction Mycobacterium tuberculosis Tuberculous lymphadenitis Early Diagnosis PCR Polimerase chain reaction Mycobacterium tuberculosis |
description |
Introduction: Tuberculous lymphadenitis (TL) is one of the most common forms of extrapulmonary tuberculosis. It’s also the most frequent manifestation in head and neck region. Objectives: Present cases of cervical TL diagnosed in ENT department of Hospital Garcia de Orta. Propose of a protocol of diagnostic investigation, with focus on excisional biopsy to get material to histological, cultural, and molecular study. Material and Methods: Retrospective study. Descriptive analysis of cases of TL diagnosed in ENT department of Hospital Garcia de Orta with consultation of clinical records. Results and Conclusions: This study analyzed 7 cases diagnosed with cervical TL. The patients were mostly female and immunocompetent. The definitive diagnosis was only possible after excisional biopsy of an adenopathy and its histological, cultural and molecular (nucleic acid amplification test PCR) examination. In most cases, the diagnose was only possible with combination of histological and molecular results. The authors propose that in suspected cases, after exclusion of malignancy with CAAF, it should be performed a excisional biopsy with histological, cultural and molecular analyses. This form of actuation will enhance the probability of a correct and prompt diagnosis. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-18 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.34631/sporl.1025 https://doi.org/10.34631/sporl.1025 |
url |
https://doi.org/10.34631/sporl.1025 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://journalsporl.com/index.php/sporl/article/view/2105 https://journalsporl.com/index.php/sporl/article/view/2105/105 https://journalsporl.com/index.php/sporl/article/view/2105/106 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2022 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2022 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço |
dc.source.none.fl_str_mv |
Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 60 No. 4 (2022): December; 295-300 Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 60 Núm. 4 (2022): Dezembro; 295-300 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 60 N.º 4 (2022): Dezembro; 295-300 2184-6499 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799136782582808576 |