Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/151587 |
Resumo: | Background: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). Precise HIV burden information is critical for effective geographic and epidemiological targeting of prevention and treatment interventions. Age- and sex-specific HIV prevalence estimates are widely available at the national level, and region-wide local estimates were recently published for adults overall. We add further dimensionality to previous analyses by estimating HIV prevalence at local scales, stratified into sex-specific 5-year age groups for adults ages 15–59 years across SSA. Methods: We analyzed data from 91 seroprevalence surveys and sentinel surveillance among antenatal care clinic (ANC) attendees using model-based geostatistical methods to produce estimates of HIV prevalence across 43 countries in SSA, from years 2000 to 2018, at a 5 × 5-km resolution and presented among second administrative level (typically districts or counties) units. Results: We found substantial variation in HIV prevalence across localities, ages, and sexes that have been masked in earlier analyses. Within-country variation in prevalence in 2018 was a median 3.5 times greater across ages and sexes, compared to for all adults combined. We note large within-district prevalence differences between age groups: for men, 50% of districts displayed at least a 14-fold difference between age groups with the highest and lowest prevalence, and at least a 9-fold difference for women. Prevalence trends also varied over time; between 2000 and 2018, 70% of all districts saw a reduction in prevalence greater than five percentage points in at least one sex and age group. Meanwhile, over 30% of all districts saw at least a five percentage point prevalence increase in one or more sex and age group. Conclusions: As the HIV epidemic persists and evolves in SSA, geographic and demographic shifts in prevention and treatment efforts are necessary. These estimates offer epidemiologically informative detail to better guide more targeted interventions, vital for combating HIV in SSA. © 2022, The Author(s). |
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Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018Africa; Demographics; Geostatistics; HIV; HIV prevalence; Mapping; Spatial statisticsBackground: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). Precise HIV burden information is critical for effective geographic and epidemiological targeting of prevention and treatment interventions. Age- and sex-specific HIV prevalence estimates are widely available at the national level, and region-wide local estimates were recently published for adults overall. We add further dimensionality to previous analyses by estimating HIV prevalence at local scales, stratified into sex-specific 5-year age groups for adults ages 15–59 years across SSA. Methods: We analyzed data from 91 seroprevalence surveys and sentinel surveillance among antenatal care clinic (ANC) attendees using model-based geostatistical methods to produce estimates of HIV prevalence across 43 countries in SSA, from years 2000 to 2018, at a 5 × 5-km resolution and presented among second administrative level (typically districts or counties) units. Results: We found substantial variation in HIV prevalence across localities, ages, and sexes that have been masked in earlier analyses. Within-country variation in prevalence in 2018 was a median 3.5 times greater across ages and sexes, compared to for all adults combined. We note large within-district prevalence differences between age groups: for men, 50% of districts displayed at least a 14-fold difference between age groups with the highest and lowest prevalence, and at least a 9-fold difference for women. Prevalence trends also varied over time; between 2000 and 2018, 70% of all districts saw a reduction in prevalence greater than five percentage points in at least one sex and age group. Meanwhile, over 30% of all districts saw at least a five percentage point prevalence increase in one or more sex and age group. Conclusions: As the HIV epidemic persists and evolves in SSA, geographic and demographic shifts in prevention and treatment efforts are necessary. These estimates offer epidemiologically informative detail to better guide more targeted interventions, vital for combating HIV in SSA. © 2022, The Author(s).BMC20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/151587eng1741-701510.1186/s12916-022-02639-zHaeuser, ESerfes, ALCork, MAYang, MAbbastabar, HAbhilash, ESAdabi, MAdebayo, OMAdekanmbi, VAdeyinka, DAAfzal, SAhinkorah, BOAhmadi, KAhmed, MBAkalu, YAkinyemi, ROAkunna, CJAlahdab, FAlanezi, FMAlanzi, TMAlene, KAAlhassan, RKAlipour, VAlmasi-Hashiani, AAlvis-Guzman, NAmeyaw, EKAmini, SAmugsi, DAAncuceanu, RAnvari, DAppiah, SCYArabloo, JAremu, OAsemahagn, MAJafarabadi, MAAwedew, AFQuintanilla, BPAAyanore, MAAynalem, YAAzari, SAzene, ZNDarshan, BBBabalola, TKBaig, AABanach, MBärnighausen, TWBell, AWBhagavathula, ASBhardwaj, NBhardwaj, PBhattacharyya, KBijani, ABitew, ZWBohlouli, SBolarinwa, OABoloor, ABozicevic, IButt, ZACárdenas, RCarvalho, FCharan, JChattu, VKChowdhury, MAKChu, D-TCowden, RGDahlawi, SMADamiani, GDarteh, EKMDarwesh, AMdas Neves, JWeaver, NDDe Leo, DDe Neve, J-WDeribe, KDeuba, KDharmaratne, SDianatinasab, MDiaz, DDidarloo, ADjalalinia, SDorostkar, FDubljanin, EDuko, BEl Tantawi, MEl-Jaafary, SIEshrati, BEskandarieh, SEyawo, OEzeonwumelu, IJEzzikouri, SFarzadfar, FFattahi, NFauk, NKFernandes, EFilip, IFischer, FFoigt, NAForoutan, MFukumoto, TGad, MMGaidhane, AMGebregiorgis, BGGebremedhin, KBGetacher, LGhadiri, KGhashghaee, AGolechha, MGubari, MIMGugnani, HCGuimarães, RAHaider, MRHaj-Mirzaian, AHamidi, SHashi, AHassanipour, SHassankhani, HHayat, KHerteliu, CHo, HCHolla, RHosseini, MHosseinzadeh, MHwang, B-FIbitoye, SEIlesanmi, OSIlic, IMIlic, MDIslam, RMIwu, CCDJakovljevic, MJha, RPJi, JSJohnson, KBJoseph, NJoshua, VJoukar, FJozwiak, JJKalankesh, LRKalhor, RKamyari, NKanchan, TMatin, BKKarimi, SEKayode, GAKaryani, AKKeramati, MKhan, EAKhan, GKhan, MNKhatab, KKhubchandani, JKim, YJKisa, AKisa, SKopec, JAKosen, SLaxminarayana, SLKKoyanagi, AKrishan, KDefo, BKKugbey, NKulkarni, VKumar, MKumar, NKusuma, DLa Vecchia, CLal, DKLandires, ILarson, HJLasrado, SLee, PHLi, SLiu, XMaleki, AMalik, PMansournia, MAMartins-Melo, FRMendoza, WMenezes, RGMengesha, EWMeretoja, TJMestrovic, TMirica, AMoazen, BMohamad, OMohammad, YMohammadian-Hafshejani, AMohammadpourhodki, RMohammed, SMohammed, SMokdad, AHMoradi, MMoraga, PMubarik, SMulu, GBBMwanri, LNagarajan, AJNaimzada, MDNaveed, MNazari, JNdejjo, RNegoi, INgalesoni, FNNguefack-Tsague, GNgunjiri, JWNguyen, CTNguyen, HLTNnaji, CANoubiap, JJNuñez-Samudio, VNwatah, VEOancea, BOdukoya, OOOlagunju, ATOlakunde, BOOlusanya, BOOlusanya, JOBali, AOOnwujekwe, OEOrisakwe, OEOtstavnov, NOtstavnov, SSOwolabi, MOMahesh, PAPadubidri, JRPana, APandey, APandi-Perumal, SRKan, FPPatton, GCPawar, SPeprah, EKPostma, MJPreotescu, LSyed, ZQRabiee, NRadfar, ARafiei, ARahim, FRahimi-Movaghar, VRahmani, AMRamezanzadeh, KRana, JRanabhat, CLRao, SJRawaf, DLRawaf, SRawassizadeh, RRegassa, LDRezaei, NRezapour, ARiaz, MARibeiro, AIRoss, JMRubagotti, ERumisha, SFRwegerera, GMMoghaddam, SSSagar, RSahiledengle, BSahu, MSalem, MRKafil, HSSamy, AMSartorius, BSathian, BSeidu, A-AShaheen, AAShaikh, MAShamsizadeh, MShiferaw, WSShin, JIShrestha, RSingh, JASkryabin, VYSkryabina, AASoltani, SSufiyan, MBTabuchi, TTadesse, EGTaveira, NTesfay, FHThapar, RTovani-Palone, MRTsegaye, GWUmeokonkwo, CDUnnikrishnan, BVillafañe, JHViolante, FSVo, BVu, GTWado, YDWaheed, YWamai, RGWang, YWard, PWickramasinghe, NDWilson, KYaya, SYip, PYonemoto, NYu, CZastrozhin, MSZhang, YZhang, Z-JHay, SIDwyer-Lindgren, Linfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:26:02Zoai:repositorio-aberto.up.pt:10216/151587Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:23:36.949837Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
title |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
spellingShingle |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 Haeuser, E Africa; Demographics; Geostatistics; HIV; HIV prevalence; Mapping; Spatial statistics |
title_short |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
title_full |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
title_fullStr |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
title_full_unstemmed |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
title_sort |
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018 |
author |
Haeuser, E |
author_facet |
Haeuser, E Serfes, AL Cork, MA Yang, M Abbastabar, H Abhilash, ES Adabi, M Adebayo, OM Adekanmbi, V Adeyinka, DA Afzal, S Ahinkorah, BO Ahmadi, K Ahmed, MB Akalu, Y Akinyemi, RO Akunna, CJ Alahdab, F Alanezi, FM Alanzi, TM Alene, KA Alhassan, RK Alipour, V Almasi-Hashiani, A Alvis-Guzman, N Ameyaw, EK Amini, S Amugsi, DA Ancuceanu, R Anvari, D Appiah, SCY Arabloo, J Aremu, O Asemahagn, MA Jafarabadi, MA Awedew, AF Quintanilla, BPA Ayanore, MA Aynalem, YA Azari, S Azene, ZN Darshan, BB Babalola, TK Baig, AA Banach, M Bärnighausen, TW Bell, AW Bhagavathula, AS Bhardwaj, N Bhardwaj, P Bhattacharyya, K Bijani, A Bitew, ZW Bohlouli, S Bolarinwa, OA Boloor, A Bozicevic, I Butt, ZA Cárdenas, R Carvalho, F Charan, J Chattu, VK Chowdhury, MAK Chu, D-T Cowden, RG Dahlawi, SMA Damiani, G Darteh, EKM Darwesh, AM das Neves, J Weaver, ND De Leo, D De Neve, J-W Deribe, K Deuba, K Dharmaratne, S Dianatinasab, M Diaz, D Didarloo, A Djalalinia, S Dorostkar, F Dubljanin, E Duko, B El Tantawi, M El-Jaafary, SI Eshrati, B Eskandarieh, S Eyawo, O Ezeonwumelu, IJ Ezzikouri, S Farzadfar, F Fattahi, N Fauk, NK Fernandes, E Filip, I Fischer, F Foigt, NA Foroutan, M Fukumoto, T Gad, MM Gaidhane, AM Gebregiorgis, BG Gebremedhin, KB Getacher, L Ghadiri, K Ghashghaee, A Golechha, M Gubari, MIM Gugnani, HC Guimarães, RA Haider, MR Haj-Mirzaian, A Hamidi, S Hashi, A Hassanipour, S Hassankhani, H Hayat, K Herteliu, C Ho, HC Holla, R Hosseini, M Hosseinzadeh, M Hwang, B-F Ibitoye, SE Ilesanmi, OS Ilic, IM Ilic, MD Islam, RM Iwu, CCD Jakovljevic, M Jha, RP Ji, JS Johnson, KB Joseph, N Joshua, V Joukar, F Jozwiak, JJ Kalankesh, LR Kalhor, R Kamyari, N Kanchan, T Matin, BK Karimi, SE Kayode, GA Karyani, AK Keramati, M Khan, EA Khan, G Khan, MN Khatab, K Khubchandani, J Kim, YJ Kisa, A Kisa, S Kopec, JA Kosen, S Laxminarayana, SLK Koyanagi, A Krishan, K Defo, BK Kugbey, N Kulkarni, V Kumar, M Kumar, N Kusuma, D La Vecchia, C Lal, DK Landires, I Larson, HJ Lasrado, S Lee, PH Li, S Liu, X Maleki, A Malik, P Mansournia, MA Martins-Melo, FR Mendoza, W Menezes, RG Mengesha, EW Meretoja, TJ Mestrovic, T Mirica, A Moazen, B Mohamad, O Mohammad, Y Mohammadian-Hafshejani, A Mohammadpourhodki, R Mohammed, S Mokdad, AH Moradi, M Moraga, P Mubarik, S Mulu, GBB Mwanri, L Nagarajan, AJ Naimzada, MD Naveed, M Nazari, J Ndejjo, R Negoi, I Ngalesoni, FN Nguefack-Tsague, G Ngunjiri, JW Nguyen, CT Nguyen, HLT Nnaji, CA Noubiap, JJ Nuñez-Samudio, V Nwatah, VE Oancea, B Odukoya, OO Olagunju, AT Olakunde, BO Olusanya, BO Olusanya, JO Bali, AO Onwujekwe, OE Orisakwe, OE Otstavnov, N Otstavnov, SS Owolabi, MO Mahesh, PA Padubidri, JR Pana, A Pandey, A Pandi-Perumal, SR Kan, FP Patton, GC Pawar, S Peprah, EK Postma, MJ Preotescu, L Syed, ZQ Rabiee, N Radfar, A Rafiei, A Rahim, F Rahimi-Movaghar, V Rahmani, AM Ramezanzadeh, K Rana, J Ranabhat, CL Rao, SJ Rawaf, DL Rawaf, S Rawassizadeh, R Regassa, LD Rezaei, N Rezapour, A Riaz, MA Ribeiro, AI Ross, JM Rubagotti, E Rumisha, SF Rwegerera, GM Moghaddam, SS Sagar, R Sahiledengle, B Sahu, M Salem, MR Kafil, HS Samy, AM Sartorius, B Sathian, B Seidu, A-A Shaheen, AA Shaikh, MA Shamsizadeh, M Shiferaw, WS Shin, JI Shrestha, R Singh, JA Skryabin, VY Skryabina, AA Soltani, S Sufiyan, MB Tabuchi, T Tadesse, EG Taveira, N Tesfay, FH Thapar, R Tovani-Palone, MR Tsegaye, GW Umeokonkwo, CD Unnikrishnan, B Villafañe, JH Violante, FS Vo, B Vu, GT Wado, YD Waheed, Y Wamai, RG Wang, Y Ward, P Wickramasinghe, ND Wilson, K Yaya, S Yip, P Yonemoto, N Yu, C Zastrozhin, MS Zhang, Y Zhang, Z-J Hay, SI Dwyer-Lindgren, L |
author_role |
author |
author2 |
Serfes, AL Cork, MA Yang, M Abbastabar, H Abhilash, ES Adabi, M Adebayo, OM Adekanmbi, V Adeyinka, DA Afzal, S Ahinkorah, BO Ahmadi, K Ahmed, MB Akalu, Y Akinyemi, RO Akunna, CJ Alahdab, F Alanezi, FM Alanzi, TM Alene, KA Alhassan, RK Alipour, V Almasi-Hashiani, A Alvis-Guzman, N Ameyaw, EK Amini, S Amugsi, DA Ancuceanu, R Anvari, D Appiah, SCY Arabloo, J Aremu, O Asemahagn, MA Jafarabadi, MA Awedew, AF Quintanilla, BPA Ayanore, MA Aynalem, YA Azari, S Azene, ZN Darshan, BB Babalola, TK Baig, AA Banach, M Bärnighausen, TW Bell, AW Bhagavathula, AS Bhardwaj, N Bhardwaj, P Bhattacharyya, K Bijani, A Bitew, ZW Bohlouli, S Bolarinwa, OA Boloor, A Bozicevic, I Butt, ZA Cárdenas, R Carvalho, F Charan, J Chattu, VK Chowdhury, MAK Chu, D-T Cowden, RG Dahlawi, SMA Damiani, G Darteh, EKM Darwesh, AM das Neves, J Weaver, ND De Leo, D De Neve, J-W Deribe, K Deuba, K Dharmaratne, S Dianatinasab, M Diaz, D Didarloo, A Djalalinia, S Dorostkar, F Dubljanin, E Duko, B El Tantawi, M El-Jaafary, SI Eshrati, B Eskandarieh, S Eyawo, O Ezeonwumelu, IJ Ezzikouri, S Farzadfar, F Fattahi, N Fauk, NK Fernandes, E Filip, I Fischer, F Foigt, NA Foroutan, M Fukumoto, T Gad, MM Gaidhane, AM Gebregiorgis, BG Gebremedhin, KB Getacher, L Ghadiri, K Ghashghaee, A Golechha, M Gubari, MIM Gugnani, HC Guimarães, RA Haider, MR Haj-Mirzaian, A Hamidi, S Hashi, A Hassanipour, S Hassankhani, H Hayat, K Herteliu, C Ho, HC Holla, R Hosseini, M Hosseinzadeh, M Hwang, B-F Ibitoye, SE Ilesanmi, OS Ilic, IM Ilic, MD Islam, RM Iwu, CCD Jakovljevic, M Jha, RP Ji, JS Johnson, KB Joseph, N Joshua, V Joukar, F Jozwiak, JJ Kalankesh, LR Kalhor, R Kamyari, N Kanchan, T Matin, BK Karimi, SE Kayode, GA Karyani, AK Keramati, M Khan, EA Khan, G Khan, MN Khatab, K Khubchandani, J Kim, YJ Kisa, A Kisa, S Kopec, JA Kosen, S Laxminarayana, SLK Koyanagi, A Krishan, K Defo, BK Kugbey, N Kulkarni, V Kumar, M Kumar, N Kusuma, D La Vecchia, C Lal, DK Landires, I Larson, HJ Lasrado, S Lee, PH Li, S Liu, X Maleki, A Malik, P Mansournia, MA Martins-Melo, FR Mendoza, W Menezes, RG Mengesha, EW Meretoja, TJ Mestrovic, T Mirica, A Moazen, B Mohamad, O Mohammad, Y Mohammadian-Hafshejani, A Mohammadpourhodki, R Mohammed, S Mokdad, AH Moradi, M Moraga, P Mubarik, S Mulu, GBB Mwanri, L Nagarajan, AJ Naimzada, MD Naveed, M Nazari, J Ndejjo, R Negoi, I Ngalesoni, FN Nguefack-Tsague, G Ngunjiri, JW Nguyen, CT Nguyen, HLT Nnaji, CA Noubiap, JJ Nuñez-Samudio, V Nwatah, VE Oancea, B Odukoya, OO Olagunju, AT Olakunde, BO Olusanya, BO Olusanya, JO Bali, AO Onwujekwe, OE Orisakwe, OE Otstavnov, N Otstavnov, SS Owolabi, MO Mahesh, PA Padubidri, JR Pana, A Pandey, A Pandi-Perumal, SR Kan, FP Patton, GC Pawar, S Peprah, EK Postma, MJ Preotescu, L Syed, ZQ Rabiee, N Radfar, A Rafiei, A Rahim, F Rahimi-Movaghar, V Rahmani, AM Ramezanzadeh, K Rana, J Ranabhat, CL Rao, SJ Rawaf, DL Rawaf, S Rawassizadeh, R Regassa, LD Rezaei, N Rezapour, A Riaz, MA Ribeiro, AI Ross, JM Rubagotti, E Rumisha, SF Rwegerera, GM Moghaddam, SS Sagar, R Sahiledengle, B Sahu, M Salem, MR Kafil, HS Samy, AM Sartorius, B Sathian, B Seidu, A-A Shaheen, AA Shaikh, MA Shamsizadeh, M Shiferaw, WS Shin, JI Shrestha, R Singh, JA Skryabin, VY Skryabina, AA Soltani, S Sufiyan, MB Tabuchi, T Tadesse, EG Taveira, N Tesfay, FH Thapar, R Tovani-Palone, MR Tsegaye, GW Umeokonkwo, CD Unnikrishnan, B Villafañe, JH Violante, FS Vo, B Vu, GT Wado, YD Waheed, Y Wamai, RG Wang, Y Ward, P Wickramasinghe, ND Wilson, K Yaya, S Yip, P Yonemoto, N Yu, C Zastrozhin, MS Zhang, Y Zhang, Z-J Hay, SI Dwyer-Lindgren, L |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Haeuser, E Serfes, AL Cork, MA Yang, M Abbastabar, H Abhilash, ES Adabi, M Adebayo, OM Adekanmbi, V Adeyinka, DA Afzal, S Ahinkorah, BO Ahmadi, K Ahmed, MB Akalu, Y Akinyemi, RO Akunna, CJ Alahdab, F Alanezi, FM Alanzi, TM Alene, KA Alhassan, RK Alipour, V Almasi-Hashiani, A Alvis-Guzman, N Ameyaw, EK Amini, S Amugsi, DA Ancuceanu, R Anvari, D Appiah, SCY Arabloo, J Aremu, O Asemahagn, MA Jafarabadi, MA Awedew, AF Quintanilla, BPA Ayanore, MA Aynalem, YA Azari, S Azene, ZN Darshan, BB Babalola, TK Baig, AA Banach, M Bärnighausen, TW Bell, AW Bhagavathula, AS Bhardwaj, N Bhardwaj, P Bhattacharyya, K Bijani, A Bitew, ZW Bohlouli, S Bolarinwa, OA Boloor, A Bozicevic, I Butt, ZA Cárdenas, R Carvalho, F Charan, J Chattu, VK Chowdhury, MAK Chu, D-T Cowden, RG Dahlawi, SMA Damiani, G Darteh, EKM Darwesh, AM das Neves, J Weaver, ND De Leo, D De Neve, J-W Deribe, K Deuba, K Dharmaratne, S Dianatinasab, M Diaz, D Didarloo, A Djalalinia, S Dorostkar, F Dubljanin, E Duko, B El Tantawi, M El-Jaafary, SI Eshrati, B Eskandarieh, S Eyawo, O Ezeonwumelu, IJ Ezzikouri, S Farzadfar, F Fattahi, N Fauk, NK Fernandes, E Filip, I Fischer, F Foigt, NA Foroutan, M Fukumoto, T Gad, MM Gaidhane, AM Gebregiorgis, BG Gebremedhin, KB Getacher, L Ghadiri, K Ghashghaee, A Golechha, M Gubari, MIM Gugnani, HC Guimarães, RA Haider, MR Haj-Mirzaian, A Hamidi, S Hashi, A Hassanipour, S Hassankhani, H Hayat, K Herteliu, C Ho, HC Holla, R Hosseini, M Hosseinzadeh, M Hwang, B-F Ibitoye, SE Ilesanmi, OS Ilic, IM Ilic, MD Islam, RM Iwu, CCD Jakovljevic, M Jha, RP Ji, JS Johnson, KB Joseph, N Joshua, V Joukar, F Jozwiak, JJ Kalankesh, LR Kalhor, R Kamyari, N Kanchan, T Matin, BK Karimi, SE Kayode, GA Karyani, AK Keramati, M Khan, EA Khan, G Khan, MN Khatab, K Khubchandani, J Kim, YJ Kisa, A Kisa, S Kopec, JA Kosen, S Laxminarayana, SLK Koyanagi, A Krishan, K Defo, BK Kugbey, N Kulkarni, V Kumar, M Kumar, N Kusuma, D La Vecchia, C Lal, DK Landires, I Larson, HJ Lasrado, S Lee, PH Li, S Liu, X Maleki, A Malik, P Mansournia, MA Martins-Melo, FR Mendoza, W Menezes, RG Mengesha, EW Meretoja, TJ Mestrovic, T Mirica, A Moazen, B Mohamad, O Mohammad, Y Mohammadian-Hafshejani, A Mohammadpourhodki, R Mohammed, S Mohammed, S Mokdad, AH Moradi, M Moraga, P Mubarik, S Mulu, GBB Mwanri, L Nagarajan, AJ Naimzada, MD Naveed, M Nazari, J Ndejjo, R Negoi, I Ngalesoni, FN Nguefack-Tsague, G Ngunjiri, JW Nguyen, CT Nguyen, HLT Nnaji, CA Noubiap, JJ Nuñez-Samudio, V Nwatah, VE Oancea, B Odukoya, OO Olagunju, AT Olakunde, BO Olusanya, BO Olusanya, JO Bali, AO Onwujekwe, OE Orisakwe, OE Otstavnov, N Otstavnov, SS Owolabi, MO Mahesh, PA Padubidri, JR Pana, A Pandey, A Pandi-Perumal, SR Kan, FP Patton, GC Pawar, S Peprah, EK Postma, MJ Preotescu, L Syed, ZQ Rabiee, N Radfar, A Rafiei, A Rahim, F Rahimi-Movaghar, V Rahmani, AM Ramezanzadeh, K Rana, J Ranabhat, CL Rao, SJ Rawaf, DL Rawaf, S Rawassizadeh, R Regassa, LD Rezaei, N Rezapour, A Riaz, MA Ribeiro, AI Ross, JM Rubagotti, E Rumisha, SF Rwegerera, GM Moghaddam, SS Sagar, R Sahiledengle, B Sahu, M Salem, MR Kafil, HS Samy, AM Sartorius, B Sathian, B Seidu, A-A Shaheen, AA Shaikh, MA Shamsizadeh, M Shiferaw, WS Shin, JI Shrestha, R Singh, JA Skryabin, VY Skryabina, AA Soltani, S Sufiyan, MB Tabuchi, T Tadesse, EG Taveira, N Tesfay, FH Thapar, R Tovani-Palone, MR Tsegaye, GW Umeokonkwo, CD Unnikrishnan, B Villafañe, JH Violante, FS Vo, B Vu, GT Wado, YD Waheed, Y Wamai, RG Wang, Y Ward, P Wickramasinghe, ND Wilson, K Yaya, S Yip, P Yonemoto, N Yu, C Zastrozhin, MS Zhang, Y Zhang, Z-J Hay, SI Dwyer-Lindgren, L |
dc.subject.por.fl_str_mv |
Africa; Demographics; Geostatistics; HIV; HIV prevalence; Mapping; Spatial statistics |
topic |
Africa; Demographics; Geostatistics; HIV; HIV prevalence; Mapping; Spatial statistics |
description |
Background: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). Precise HIV burden information is critical for effective geographic and epidemiological targeting of prevention and treatment interventions. Age- and sex-specific HIV prevalence estimates are widely available at the national level, and region-wide local estimates were recently published for adults overall. We add further dimensionality to previous analyses by estimating HIV prevalence at local scales, stratified into sex-specific 5-year age groups for adults ages 15–59 years across SSA. Methods: We analyzed data from 91 seroprevalence surveys and sentinel surveillance among antenatal care clinic (ANC) attendees using model-based geostatistical methods to produce estimates of HIV prevalence across 43 countries in SSA, from years 2000 to 2018, at a 5 × 5-km resolution and presented among second administrative level (typically districts or counties) units. Results: We found substantial variation in HIV prevalence across localities, ages, and sexes that have been masked in earlier analyses. Within-country variation in prevalence in 2018 was a median 3.5 times greater across ages and sexes, compared to for all adults combined. We note large within-district prevalence differences between age groups: for men, 50% of districts displayed at least a 14-fold difference between age groups with the highest and lowest prevalence, and at least a 9-fold difference for women. Prevalence trends also varied over time; between 2000 and 2018, 70% of all districts saw a reduction in prevalence greater than five percentage points in at least one sex and age group. Meanwhile, over 30% of all districts saw at least a five percentage point prevalence increase in one or more sex and age group. Conclusions: As the HIV epidemic persists and evolves in SSA, geographic and demographic shifts in prevention and treatment efforts are necessary. These estimates offer epidemiologically informative detail to better guide more targeted interventions, vital for combating HIV in SSA. © 2022, The Author(s). |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 2022-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/151587 |
url |
https://hdl.handle.net/10216/151587 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1741-7015 10.1186/s12916-022-02639-z |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMC |
publisher.none.fl_str_mv |
BMC |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799136151866441728 |