Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries
| Autor(a) principal: | |
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| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/8409 |
Resumo: | [Corrections added after online publication, 16 November 2022: The last name of Dr. Jennifer M. Broughan was incorrectly spelled in the initial publication. It has been corrected.] |
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Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countriesCongenital AnomaliesVascular DisruptionMaternal AgeEUROCATEuropean Surveillance of Congenital AnomaliesEuropeRENACRegisto Nacional de Anomalias CongénitasEstados de Saúde e de DoençaObservação em Saúde e VigilânciaPortugal[Corrections added after online publication, 16 November 2022: The last name of Dr. Jennifer M. Broughan was incorrectly spelled in the initial publication. It has been corrected.]Background: Younger mothers are at a greater risk of having a pregnancy with gastroschisis and the risk is higher in the United Kingdom than other European countries. Gastroschisis is thought to be a vascular disruption anomaly and the aim of this study was to analyze the prevalence of other possible vascular disruption anomalies to determine whether both the younger maternal age and the UK associations also occur with these anomalies. Methods: All pregnancies with anomalies considered potentially due to vascular disruption from January 1, 2005 to December 31, 2017 from 26 European population-based congenital anomaly registries who were members of EUROCAT were analyzed. Multilevel models were used to allow for differences between registries when analyzing associations with maternal age, year of birth and whether the registry was in the United Kingdom. Results: There were 5,220 cases with potential vascular disruption anomalies, excluding chromosomal and genetic conditions, with a prevalence of 8.85 per 10,000 births in the United Kingdom and 5.44 in the other European countries. The prevalence per 10,000 births of gastroschisis (4.45 vs. 1.56) and congenital constriction bands (0.83 vs. 0.42) was significantly higher in the United Kingdom, even after adjusting for maternal age. However, transverse limb reduction defects had a similar prevalence (2.16 vs. 2.14 per 10,000). The expected increased prevalence in younger mothers was observed for vascular disruption anomalies overall and for the individual anomalies: gastroschisis and congenital constriction bands. Conclusion: Vascular disruption anomalies that had an increased risk for younger mothers (such as gastroschisis) had a higher maternal age standardized prevalence in the United Kingdom, while vascular disruption anomalies with weaker associations with younger mothers (such as transverse limb reduction defects) did not have an increased prevalence in the United Kingdom, which may indicate a different etiology for these anomalies.European CommissionWileyRepositório Científico do Instituto Nacional de SaúdeMorris, Joan K.Wellesley, DianaLimb, ElizabethBergman, Jorieke E.H.Kinsner‐Ovaskainen, AgnieszkaAddor, Marie ClaudeBroughan, Jennifer M.Cavero‐Carbonell, ClaraMatias Dias, CarlosEchevarría‐González‐de‐Garibay, Luis‐JavierGatt, MiriamHaeusler, MartinBarisic, IngeborgKlungsoyr, KariLelong, NathalieMaterna‐Kiryluk, AnnaNeville, AmandaNelen, VeraO'Mahony, Mary T.Perthus, IsabellePierini, AnnaRankin, JudithRissmann, AnkeRouget, FlorenceSayers, GeraldineStevens, SarahTucker, DavidGarne, Ester2023-01-09T15:16:51Z2022-12-012022-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8409engBirth Defects Res . 2022 Dec 1;114(20):1417-1426. doi: 10.1002/bdr2.2122. Epub 2022 Nov 11.2472-172710.1002/bdr2.2122info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:34Zoai:repositorio.insa.pt:10400.18/8409Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:05.075806Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| title |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| spellingShingle |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries Morris, Joan K. Congenital Anomalies Vascular Disruption Maternal Age EUROCAT European Surveillance of Congenital Anomalies Europe RENAC Registo Nacional de Anomalias Congénitas Estados de Saúde e de Doença Observação em Saúde e Vigilância Portugal |
| title_short |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| title_full |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| title_fullStr |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| title_full_unstemmed |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| title_sort |
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries |
| author |
Morris, Joan K. |
| author_facet |
Morris, Joan K. Wellesley, Diana Limb, Elizabeth Bergman, Jorieke E.H. Kinsner‐Ovaskainen, Agnieszka Addor, Marie Claude Broughan, Jennifer M. Cavero‐Carbonell, Clara Matias Dias, Carlos Echevarría‐González‐de‐Garibay, Luis‐Javier Gatt, Miriam Haeusler, Martin Barisic, Ingeborg Klungsoyr, Kari Lelong, Nathalie Materna‐Kiryluk, Anna Neville, Amanda Nelen, Vera O'Mahony, Mary T. Perthus, Isabelle Pierini, Anna Rankin, Judith Rissmann, Anke Rouget, Florence Sayers, Geraldine Stevens, Sarah Tucker, David Garne, Ester |
| author_role |
author |
| author2 |
Wellesley, Diana Limb, Elizabeth Bergman, Jorieke E.H. Kinsner‐Ovaskainen, Agnieszka Addor, Marie Claude Broughan, Jennifer M. Cavero‐Carbonell, Clara Matias Dias, Carlos Echevarría‐González‐de‐Garibay, Luis‐Javier Gatt, Miriam Haeusler, Martin Barisic, Ingeborg Klungsoyr, Kari Lelong, Nathalie Materna‐Kiryluk, Anna Neville, Amanda Nelen, Vera O'Mahony, Mary T. Perthus, Isabelle Pierini, Anna Rankin, Judith Rissmann, Anke Rouget, Florence Sayers, Geraldine Stevens, Sarah Tucker, David Garne, Ester |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Morris, Joan K. Wellesley, Diana Limb, Elizabeth Bergman, Jorieke E.H. Kinsner‐Ovaskainen, Agnieszka Addor, Marie Claude Broughan, Jennifer M. Cavero‐Carbonell, Clara Matias Dias, Carlos Echevarría‐González‐de‐Garibay, Luis‐Javier Gatt, Miriam Haeusler, Martin Barisic, Ingeborg Klungsoyr, Kari Lelong, Nathalie Materna‐Kiryluk, Anna Neville, Amanda Nelen, Vera O'Mahony, Mary T. Perthus, Isabelle Pierini, Anna Rankin, Judith Rissmann, Anke Rouget, Florence Sayers, Geraldine Stevens, Sarah Tucker, David Garne, Ester |
| dc.subject.por.fl_str_mv |
Congenital Anomalies Vascular Disruption Maternal Age EUROCAT European Surveillance of Congenital Anomalies Europe RENAC Registo Nacional de Anomalias Congénitas Estados de Saúde e de Doença Observação em Saúde e Vigilância Portugal |
| topic |
Congenital Anomalies Vascular Disruption Maternal Age EUROCAT European Surveillance of Congenital Anomalies Europe RENAC Registo Nacional de Anomalias Congénitas Estados de Saúde e de Doença Observação em Saúde e Vigilância Portugal |
| description |
[Corrections added after online publication, 16 November 2022: The last name of Dr. Jennifer M. Broughan was incorrectly spelled in the initial publication. It has been corrected.] |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-12-01 2022-12-01T00:00:00Z 2023-01-09T15:16:51Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10400.18/8409 |
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http://hdl.handle.net/10400.18/8409 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Birth Defects Res . 2022 Dec 1;114(20):1417-1426. doi: 10.1002/bdr2.2122. Epub 2022 Nov 11. 2472-1727 10.1002/bdr2.2122 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Wiley |
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Wiley |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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