Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method

Detalhes bibliográficos
Autor(a) principal: Carvalho, Patrícia M.S.
Data de Publicação: 2020
Outros Autores: Pessanha, Sofia, Machado, Jorge, Silva, Ana Luísa, Veloso, João F. C. A., Casal, Diogo, Pais, Diogo, Santos, José Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/114684
Resumo: PTDC/FIS-AQM/32536/2017 through FEDER and Fundacao para a CiEncia e Tecnologia (FCT) (Portugal) UID/FIS/04559/2019 to LIBPhys-UNL from the FCT/MCTES/PIDDAC, Portugal. Patricia M. S. Carvalho acknowledges the support of FCT (Portugal) under contract No. PD/BD/128324/2017.
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spelling Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard methodCancerEnergy dispersive X-ray fluorescenceExternal standard methodQuantitative analysisTrace elementsAnalytical ChemistryAtomic and Molecular Physics, and OpticsInstrumentationSpectroscopySDG 3 - Good Health and Well-beingPTDC/FIS-AQM/32536/2017 through FEDER and Fundacao para a CiEncia e Tecnologia (FCT) (Portugal) UID/FIS/04559/2019 to LIBPhys-UNL from the FCT/MCTES/PIDDAC, Portugal. Patricia M. S. Carvalho acknowledges the support of FCT (Portugal) under contract No. PD/BD/128324/2017.Trace elements are present in minute amounts in the human body but contribute to its proper functioning, by participating in several biological processes. Imbalance of the concentrations of these elements can lead to the development of pathologies, including cancer. As such, the determination of trace element content in tumour tissues and its comparison with normal ones may be helpful for a better understanding of carcinogenesis. In this work, we address the collection and preparation of biological samples for Energy Dispersive X-Ray Fluorescence (EDXRF) analysis, and present a model for the quantification of trace elements, based on the external standard method of quantification. The model was used for the quantification of iron, copper, and zinc in a set of paired samples (normal and tumour tissues). The obtained results show the validity of the method and variations of the elemental concentrations in the different tissues.LIBPhys-UNLNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNCarvalho, Patrícia M.S.Pessanha, SofiaMachado, JorgeSilva, Ana LuísaVeloso, João F. C. A.Casal, DiogoPais, DiogoSantos, José Paulo2022-10-15T00:33:11Z2020-122020-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/114684eng0584-8547PURE: 26053094https://doi.org/10.1016/j.sab.2020.105991info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:57:21Zoai:run.unl.pt:10362/114684Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:36.185527Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
title Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
spellingShingle Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
Carvalho, Patrícia M.S.
Cancer
Energy dispersive X-ray fluorescence
External standard method
Quantitative analysis
Trace elements
Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Spectroscopy
SDG 3 - Good Health and Well-being
title_short Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
title_full Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
title_fullStr Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
title_full_unstemmed Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
title_sort Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method
author Carvalho, Patrícia M.S.
author_facet Carvalho, Patrícia M.S.
Pessanha, Sofia
Machado, Jorge
Silva, Ana Luísa
Veloso, João F. C. A.
Casal, Diogo
Pais, Diogo
Santos, José Paulo
author_role author
author2 Pessanha, Sofia
Machado, Jorge
Silva, Ana Luísa
Veloso, João F. C. A.
Casal, Diogo
Pais, Diogo
Santos, José Paulo
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv LIBPhys-UNL
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Carvalho, Patrícia M.S.
Pessanha, Sofia
Machado, Jorge
Silva, Ana Luísa
Veloso, João F. C. A.
Casal, Diogo
Pais, Diogo
Santos, José Paulo
dc.subject.por.fl_str_mv Cancer
Energy dispersive X-ray fluorescence
External standard method
Quantitative analysis
Trace elements
Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Spectroscopy
SDG 3 - Good Health and Well-being
topic Cancer
Energy dispersive X-ray fluorescence
External standard method
Quantitative analysis
Trace elements
Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Spectroscopy
SDG 3 - Good Health and Well-being
description PTDC/FIS-AQM/32536/2017 through FEDER and Fundacao para a CiEncia e Tecnologia (FCT) (Portugal) UID/FIS/04559/2019 to LIBPhys-UNL from the FCT/MCTES/PIDDAC, Portugal. Patricia M. S. Carvalho acknowledges the support of FCT (Portugal) under contract No. PD/BD/128324/2017.
publishDate 2020
dc.date.none.fl_str_mv 2020-12
2020-12-01T00:00:00Z
2022-10-15T00:33:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/114684
url http://hdl.handle.net/10362/114684
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0584-8547
PURE: 26053094
https://doi.org/10.1016/j.sab.2020.105991
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138036981694464

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