Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/58138 |
Resumo: | © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patientsChildrenJuvenile idiopathic arthritisLatent tuberculosis infectionRheumatic diseasesTuberculosis© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Background: Rheumatic diseases are associated with an increase in overall risks of tuberculosis (TB). The aim of this study was to evaluate the frequency of TB and the frequency of latent TB infection (LTBI), in clinical practice, for juvenile idiopathic arthritis (JIA) patients from high and low risk of TB incidence endemic countries. Methods: This is an international, multicenter, cross-sectional, observational study of data collection from Brazil and Registry of Portugal at REUMA.PT. The inclusion criteria were patients with Juvenile Idiopathic Arthritis (JIA) with age ≤ 18 years who underwent screening for Mycobacterium tuberculosis infection [tuberculin skin test (TST) and/or interferon gamma release assay (IGRA)]. Chest X-rays and history of exposure to TB were also assessed. Results: 292 JIA patients were included; mean age 14.3 years, mean disease duration 7.5 years, 194 patients (66.4%) performed only TST, 14 (4.8%) only IGRA and 84 (28.8%) both. The frequency of LTBI (10.6%) and TB was similar between the two countries. The reasons for TB screening were different; in Brazil it was performed more often at JIA onset while in Portugal it was performed when starting Disease Modified Anti-Rheumatic Drugs (DMARD) treatment (p < 0.001). Isoniazid therapy was prescribed in 40 (13.7%) patients (31 with LTBI and 9 with epidemiologic risks and/or due to contact with sick people). Only three patients (1%) developed active TB. Conclusion: We found nearly 10% of patients with LTBI, a small percentage of patients with treatment due to epidemiologic risks and only 1% with active TB. Distinct reasons and screening methods for LTBI were observed between the two countries.Springer NatureRepositório da Universidade de LisboaPiotto, DanielaNicacio, AlineNeto, AgnaMourão, Ana FilipaOliveira Ramos, FilipaCampanilho-Marques, RaquelGuedes, MargaridaCabral, MartaSantos, MariaFonseca, João EuricoCanhao, HelenaAikawa, Nádia EmiOliveira, Sheila K. F.Ferriani, Virginia P. L.Pileggi, Gecilmara C. S.Magalhães, Claudia S.Silva, Clovis ArturTerreri, Maria Teresa2023-06-09T13:23:32Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/58138engAdv Rheumatol. 2022 Jun 10;62(1):2010.1186/s42358-022-00251-62523-3106info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:06:44Zoai:repositorio.ul.pt:10451/58138Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:08:22.556044Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| title |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| spellingShingle |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients Piotto, Daniela Children Juvenile idiopathic arthritis Latent tuberculosis infection Rheumatic diseases Tuberculosis |
| title_short |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| title_full |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| title_fullStr |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| title_full_unstemmed |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| title_sort |
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients |
| author |
Piotto, Daniela |
| author_facet |
Piotto, Daniela Nicacio, Aline Neto, Agna Mourão, Ana Filipa Oliveira Ramos, Filipa Campanilho-Marques, Raquel Guedes, Margarida Cabral, Marta Santos, Maria Fonseca, João Eurico Canhao, Helena Aikawa, Nádia Emi Oliveira, Sheila K. F. Ferriani, Virginia P. L. Pileggi, Gecilmara C. S. Magalhães, Claudia S. Silva, Clovis Artur Terreri, Maria Teresa |
| author_role |
author |
| author2 |
Nicacio, Aline Neto, Agna Mourão, Ana Filipa Oliveira Ramos, Filipa Campanilho-Marques, Raquel Guedes, Margarida Cabral, Marta Santos, Maria Fonseca, João Eurico Canhao, Helena Aikawa, Nádia Emi Oliveira, Sheila K. F. Ferriani, Virginia P. L. Pileggi, Gecilmara C. S. Magalhães, Claudia S. Silva, Clovis Artur Terreri, Maria Teresa |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Piotto, Daniela Nicacio, Aline Neto, Agna Mourão, Ana Filipa Oliveira Ramos, Filipa Campanilho-Marques, Raquel Guedes, Margarida Cabral, Marta Santos, Maria Fonseca, João Eurico Canhao, Helena Aikawa, Nádia Emi Oliveira, Sheila K. F. Ferriani, Virginia P. L. Pileggi, Gecilmara C. S. Magalhães, Claudia S. Silva, Clovis Artur Terreri, Maria Teresa |
| dc.subject.por.fl_str_mv |
Children Juvenile idiopathic arthritis Latent tuberculosis infection Rheumatic diseases Tuberculosis |
| topic |
Children Juvenile idiopathic arthritis Latent tuberculosis infection Rheumatic diseases Tuberculosis |
| description |
© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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2022 |
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2022 2022-01-01T00:00:00Z 2023-06-09T13:23:32Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/58138 |
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http://hdl.handle.net/10451/58138 |
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eng |
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eng |
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Adv Rheumatol. 2022 Jun 10;62(1):20 10.1186/s42358-022-00251-6 2523-3106 |
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application/pdf |
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Springer Nature |
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Springer Nature |
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