Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia

Detalhes bibliográficos
Autor(a) principal: Mendonça, Marcelo D
Data de Publicação: 2019
Outros Autores: Seromenho-Santos, Alexandra, Caetano, André, Reizinho, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/87145
Resumo: Patients with demyelinating diseases (DDs) such as multiple sclerosis have a 20-fold higher risk of developing trigeminal neuralgia (TN). DD-related TN is more frequently refractory to the usual medical and surgical treatment. We report the case of a 57-year-old man presenting to our neurology outpatient clinic with a 12-year history of medical and surgical refractory TN associated with demyelinating lesions on magnetic resonance imaging. After a new failure of pharmacological treatment with oxcarbazepine, pregabalin, baclofen, and duloxetine, motor cortex stimulation (MCS) was performed, and the patient remained mostly pain-free, without any pharmacological treatment during the 3.5 years of follow-up. MCS may be a useful approach for DD-related refractory TN, and further studies can clarify its role in TN management.
id RCAP_c960fdbc8d789a9ca6f980991cc5700b
oai_identifier_str oai:run.unl.pt:10362/87145
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgiamotor cortex stimulationpainrefractorytrigeminal neuralgiaPatients with demyelinating diseases (DDs) such as multiple sclerosis have a 20-fold higher risk of developing trigeminal neuralgia (TN). DD-related TN is more frequently refractory to the usual medical and surgical treatment. We report the case of a 57-year-old man presenting to our neurology outpatient clinic with a 12-year history of medical and surgical refractory TN associated with demyelinating lesions on magnetic resonance imaging. After a new failure of pharmacological treatment with oxcarbazepine, pregabalin, baclofen, and duloxetine, motor cortex stimulation (MCS) was performed, and the patient remained mostly pain-free, without any pharmacological treatment during the 3.5 years of follow-up. MCS may be a useful approach for DD-related refractory TN, and further studies can clarify its role in TN management.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNMendonça, Marcelo DSeromenho-Santos, AlexandraCaetano, AndréReizinho, Carla2019-11-13T04:40:55Z2019-07-302019-07-30T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/87145eng2515-8163PURE: 14304625https://doi.org/10.1177/2515816319866149info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:38:54Zoai:run.unl.pt:10362/87145Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:36:43.949280Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
title Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
spellingShingle Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
Mendonça, Marcelo D
motor cortex stimulation
pain
refractory
trigeminal neuralgia
title_short Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
title_full Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
title_fullStr Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
title_full_unstemmed Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
title_sort Motor cortex stimulation for refractory demyelinating disease-associated trigeminal neuralgia
author Mendonça, Marcelo D
author_facet Mendonça, Marcelo D
Seromenho-Santos, Alexandra
Caetano, André
Reizinho, Carla
author_role author
author2 Seromenho-Santos, Alexandra
Caetano, André
Reizinho, Carla
author2_role author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Centro de Estudos de Doenças Crónicas (CEDOC)
RUN
dc.contributor.author.fl_str_mv Mendonça, Marcelo D
Seromenho-Santos, Alexandra
Caetano, André
Reizinho, Carla
dc.subject.por.fl_str_mv motor cortex stimulation
pain
refractory
trigeminal neuralgia
topic motor cortex stimulation
pain
refractory
trigeminal neuralgia
description Patients with demyelinating diseases (DDs) such as multiple sclerosis have a 20-fold higher risk of developing trigeminal neuralgia (TN). DD-related TN is more frequently refractory to the usual medical and surgical treatment. We report the case of a 57-year-old man presenting to our neurology outpatient clinic with a 12-year history of medical and surgical refractory TN associated with demyelinating lesions on magnetic resonance imaging. After a new failure of pharmacological treatment with oxcarbazepine, pregabalin, baclofen, and duloxetine, motor cortex stimulation (MCS) was performed, and the patient remained mostly pain-free, without any pharmacological treatment during the 3.5 years of follow-up. MCS may be a useful approach for DD-related refractory TN, and further studies can clarify its role in TN management.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-13T04:40:55Z
2019-07-30
2019-07-30T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/87145
url http://hdl.handle.net/10362/87145
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2515-8163
PURE: 14304625
https://doi.org/10.1177/2515816319866149
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799137985133805568

Registros relacionados