A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens

Detalhes bibliográficos
Autor(a) principal: Soares, Sofia
Data de Publicação: 2021
Outros Autores: Barroso, Mário, Gallardo, Eugenia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/41467
https://doi.org/10.1515/revac-2021-0124
Resumo: Antidepressants are a class of compounds widely used in clinical settings for the treatment of several diseases. In the last years there has been a considerable increase in their consumption, representing an important public health issue in several countries. Because they are substances with narrow therapeutic windows, and since they are capable of interacting with other classes of compounds, monitoring of these compounds is of relevance, minimizing the risk of medical interactions as well as side and toxic effects. In addition, understanding the extent of their use, their detection through routine toxicology tests and development of new methods for detection and monitoring is of extreme importance concerning public health, patient well-being, and implications in clinical and forensic situations. The main objective of this work is to perform a critical review on the biological samples used in the detection and quantification of antidepressants with special focus on the techniques for sample preparation.
id RCAP_cb72afb2a975ddf77a5ae9432a07f6bb
oai_identifier_str oai:comum.rcaap.pt:10400.26/41467
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimensAntidepressantsBiological specimensSample pretreatment techniquesAnalytical instrumentationAntidepressants are a class of compounds widely used in clinical settings for the treatment of several diseases. In the last years there has been a considerable increase in their consumption, representing an important public health issue in several countries. Because they are substances with narrow therapeutic windows, and since they are capable of interacting with other classes of compounds, monitoring of these compounds is of relevance, minimizing the risk of medical interactions as well as side and toxic effects. In addition, understanding the extent of their use, their detection through routine toxicology tests and development of new methods for detection and monitoring is of extreme importance concerning public health, patient well-being, and implications in clinical and forensic situations. The main objective of this work is to perform a critical review on the biological samples used in the detection and quantification of antidepressants with special focus on the techniques for sample preparation.info:eu-repo/semantics/publishedVersionDe Gruyter2022-07-26T16:00:50Z2022-07-262021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/41467http://hdl.handle.net/10400.26/41467https://doi.org/10.1515/revac-2021-0124engSoares, S., Barroso, M., & Gallardo, E. (2021). A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens. Reviews in Analytical Chemistry, 40(1), 12–322191-0189https://www.degruyter.com/document/doi/10.1515/revac-2021-0124/htmlhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessSoares, SofiaBarroso, MárioGallardo, Eugeniareponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:22:03Zoai:comum.rcaap.pt:10400.26/41467Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:43.683496Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
title A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
spellingShingle A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
Soares, Sofia
Antidepressants
Biological specimens
Sample pretreatment techniques
Analytical instrumentation
title_short A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
title_full A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
title_fullStr A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
title_full_unstemmed A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
title_sort A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens
author Soares, Sofia
author_facet Soares, Sofia
Barroso, Mário
Gallardo, Eugenia
author_role author
author2 Barroso, Mário
Gallardo, Eugenia
author2_role author
author
dc.contributor.author.fl_str_mv Soares, Sofia
Barroso, Mário
Gallardo, Eugenia
dc.subject.por.fl_str_mv Antidepressants
Biological specimens
Sample pretreatment techniques
Analytical instrumentation
topic Antidepressants
Biological specimens
Sample pretreatment techniques
Analytical instrumentation
description Antidepressants are a class of compounds widely used in clinical settings for the treatment of several diseases. In the last years there has been a considerable increase in their consumption, representing an important public health issue in several countries. Because they are substances with narrow therapeutic windows, and since they are capable of interacting with other classes of compounds, monitoring of these compounds is of relevance, minimizing the risk of medical interactions as well as side and toxic effects. In addition, understanding the extent of their use, their detection through routine toxicology tests and development of new methods for detection and monitoring is of extreme importance concerning public health, patient well-being, and implications in clinical and forensic situations. The main objective of this work is to perform a critical review on the biological samples used in the detection and quantification of antidepressants with special focus on the techniques for sample preparation.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01T00:00:00Z
2022-07-26T16:00:50Z
2022-07-26
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/41467
http://hdl.handle.net/10400.26/41467
https://doi.org/10.1515/revac-2021-0124
url http://hdl.handle.net/10400.26/41467
https://doi.org/10.1515/revac-2021-0124
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Soares, S., Barroso, M., & Gallardo, E. (2021). A review of current bioanalytical approaches in sample pretreatment techniques for the determination of antidepressants in biological specimens. Reviews in Analytical Chemistry, 40(1), 12–32
2191-0189
https://www.degruyter.com/document/doi/10.1515/revac-2021-0124/html
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv De Gruyter
publisher.none.fl_str_mv De Gruyter
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799137165901299712

Registros relacionados