Development of new oxygen therapeutics using fluorinated ionic liquids

Detalhes bibliográficos
Autor(a) principal: Martinho, Susana Teresa Antunes
Data de Publicação: 2012
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/8482
Resumo: Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau Mestre em Engenharia Biomédica
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spelling Development of new oxygen therapeutics using fluorinated ionic liquidsFluorinated Ionic liquidsPerfluorocarbonsThermophysical characterizationLiquid-liquid equilibriaArtificial blood substitutesDissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau Mestre em Engenharia BiomédicaThe last decade of the 20th century has yielded a remarkable progress in the field of first generation artificial blood substitutes. Emulsions based on perfluorocarbons (PFCs) became one of the main candidates for a safe and reliable artificial blood substitute. The final objective of the present work is to study the fluorinated ionic liquids (FILs) with the purpose of replacing, partially or totally, the PFCs actually used as artificial blood substitutes, thus providing new fluids with tailored advanced properties. With this goal in mind, the thermophysical and thermodynamic characterization of several FILs, was carried out with the aim to select the most appropriate candidate. This characterization involves the measurement and analysis of the decomposition and melting temperature, density, viscosity, refractive index, and ionic conductivity at atmospheric pressure in a temperature range from 298.15 to 353.15 K. Furthermore, the liquid-liquid equilibria of binary mixtures of PFCs and FILs were studied, at atmospheric pressure in a temperature range usually from 293.15 to 343.15 K. The knowledge of the phase behaviour is crucial to the formulation of emulsions used nowadays as suitable oxygen carriers. Finally, Non-Random Two Liquid (NRTL) thermodynamic model was successfully applied to correlate the behaviour of the binary mixtures of PFCs and FILsFaculdade de Ciências e TecnologiaFerreira, IsabelEstévez, AnaSilva, Jorge CarvalhoRUNMartinho, Susana Teresa Antunes2013-01-09T14:54:45Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/8482enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T03:41:07Zoai:run.unl.pt:10362/8482Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:18:13.528727Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of new oxygen therapeutics using fluorinated ionic liquids
title Development of new oxygen therapeutics using fluorinated ionic liquids
spellingShingle Development of new oxygen therapeutics using fluorinated ionic liquids
Martinho, Susana Teresa Antunes
Fluorinated Ionic liquids
Perfluorocarbons
Thermophysical characterization
Liquid-liquid equilibria
Artificial blood substitutes
title_short Development of new oxygen therapeutics using fluorinated ionic liquids
title_full Development of new oxygen therapeutics using fluorinated ionic liquids
title_fullStr Development of new oxygen therapeutics using fluorinated ionic liquids
title_full_unstemmed Development of new oxygen therapeutics using fluorinated ionic liquids
title_sort Development of new oxygen therapeutics using fluorinated ionic liquids
author Martinho, Susana Teresa Antunes
author_facet Martinho, Susana Teresa Antunes
author_role author
dc.contributor.none.fl_str_mv Ferreira, Isabel
Estévez, Ana
Silva, Jorge Carvalho
RUN
dc.contributor.author.fl_str_mv Martinho, Susana Teresa Antunes
dc.subject.por.fl_str_mv Fluorinated Ionic liquids
Perfluorocarbons
Thermophysical characterization
Liquid-liquid equilibria
Artificial blood substitutes
topic Fluorinated Ionic liquids
Perfluorocarbons
Thermophysical characterization
Liquid-liquid equilibria
Artificial blood substitutes
description Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau Mestre em Engenharia Biomédica
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
2013-01-09T14:54:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/8482
url http://hdl.handle.net/10362/8482
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Faculdade de Ciências e Tecnologia
publisher.none.fl_str_mv Faculdade de Ciências e Tecnologia
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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