Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial

Detalhes bibliográficos
Autor(a) principal: Videira-Silva, Antonio
Data de Publicação: 2024
Outros Autores: Santos, Inês, Freaza, Dalise, Gameiro, Mariana, Sardinha, Luís B., Fonseca, Helena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/65417
Resumo: © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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spelling Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trialAdolescentsBone healthDietExerciseObesityPhysical activity© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Purpose: The present study aimed to explore the influence of diet and physical activity (PA) changes on bone mineral content (BMC) and density (BMD) alterations in adolescents with obesity undergoing a weight loss program. Methods: Six-month longitudinal data from 71 adolescents (aged 15.1 [± 1.6] years; 57.7% girls) with a BMI z-score of 3.03 (± 0.78), previously recruited for the PAC-MAnO trial, were analyzed using Generalized Estimation Equations for over time changes and linear regressions with BMC, BMD and BMD z-score as dependent variables, adjusting for confounders (including type of exercise- aerobic vs. combined). Results: Adjusting for confounders, changes in carbohydrate (CH) and protein content showed to positively and negatively predict BMD z-score variance, respectively (β = 0.44, 95%CI: 0.01, 0.04, p < .001); β = -0.57, 95%CI: -0.06, -0.03, p < .001), yet no associations were found between PA and bone-related parameters. Combined exercise showed better results on BMC compared to aerobic exercise (β = 0.09, 95%CI: 0.05 to 0.13, p < .001). Conclusions: Increased CH content, instead of protein, may be associated with BMD improvements in adolescents with obesity. Type of exercise may moderate the impact of PA on bone health. Trial registration: Clinicaltrials.gov NCT02941770. What is Known • Adolescents with obesity may be at a higher risk of osteopenia/osteoporosis • Obesity and inadequate diet and physical activity (PA) may have an adverse effect on bone metabolism What is New • Improvements in adiposity and muscle mass and increased diet carbohydrate content are associated with bone mineral density (BMD) improvements • Type of exercise (i.e., combined training vs. aerobic) may moderate the impact of PA on BMD, and calcium intake may mediate this impact.AVS was supported by the Portuguese Foundation for Science and Technology (SFRH/BD/130193/2017). Open access funding provided by FCT|FCCN (b-on). AVS was supported by the Portuguese Foundation for Science and Technology (SFRH/BD/130193/2017).Springer NatureRepositório da Universidade de LisboaVideira-Silva, AntonioSantos, InêsFreaza, DaliseGameiro, MarianaSardinha, Luís B.Fonseca, Helena2024-07-23T14:13:14Z20242024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/65417engEur J Pediatr. 2024 Jun 270340-619910.1007/s00431-024-05659-41432-1076info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-20T18:30:52Zoai:repositorio.ul.pt:10451/65417Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-20T18:30:52Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
title Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
spellingShingle Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
Videira-Silva, Antonio
Adolescents
Bone health
Diet
Exercise
Obesity
Physical activity
title_short Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
title_full Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
title_fullStr Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
title_full_unstemmed Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
title_sort Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
author Videira-Silva, Antonio
author_facet Videira-Silva, Antonio
Santos, Inês
Freaza, Dalise
Gameiro, Mariana
Sardinha, Luís B.
Fonseca, Helena
author_role author
author2 Santos, Inês
Freaza, Dalise
Gameiro, Mariana
Sardinha, Luís B.
Fonseca, Helena
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Videira-Silva, Antonio
Santos, Inês
Freaza, Dalise
Gameiro, Mariana
Sardinha, Luís B.
Fonseca, Helena
dc.subject.por.fl_str_mv Adolescents
Bone health
Diet
Exercise
Obesity
Physical activity
topic Adolescents
Bone health
Diet
Exercise
Obesity
Physical activity
description © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
publishDate 2024
dc.date.none.fl_str_mv 2024-07-23T14:13:14Z
2024
2024-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/65417
url http://hdl.handle.net/10451/65417
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eur J Pediatr. 2024 Jun 27
0340-6199
10.1007/s00431-024-05659-4
1432-1076
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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