The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/116911 |
Resumo: | PTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16 |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.AstaxanthinFungal MAT genesPhaffiaPhylogenomicsYeast taxonomyMicrobiologyMicrobiology (medical)VirologyPTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16Phaffia is an orange-colored basidiomycetous yeast genus of the order Cystofilobasidiales that contains a single species, P. rhodozyma. This species is the only fungus known to produce the economically relevant carotenoid astaxanthin. Although Phaffia was originally found in the Northern hemisphere, its diversity in the southern part of the globe has been shown to be much greater. Here we analyze the genomes of two Australasian lineages that are markedly distinct from P. rhodozyma. The two divergent lineages were investigated within a comprehensive phylogenomic study of representatives of the Cystofilobasidiales that supported the recognition of two novel Phaffia species, for which we propose the names of P. australis sp. nov. and P. tasmanica sp. nov. Comparative genomics and other analyses confirmed that the two new species have the typical Phaffia hallmark—the six genes necessary for the biosynthesis of astaxanthin could be retrieved from the draft genome sequences, and this carotenoid was detected in culture extracts. In addition, the organization of the mating-type (MAT) loci is similar to that of P. rhodozyma, with synteny throughout most regions. Moreover, cases of trans-specific polymorphism involving pheromone receptor genes and pheromone precursor proteins in the three Phaffia species, together with their shared homothallism, provide additional support for their classification in a single genus.UCIBIO - Applied Molecular Biosciences UnitDCV - Departamento de Ciências da VidaRUNDavid-Palma, MárciaLibkind, DiegoBrito, Patrícia H.Silva, MargaridaBellora, NicolásCoelho, Marco A.Heitman, JosephGonçalves, PaulaSampaio, José Paulo2021-05-03T22:56:08Z2020-10-242020-10-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article15application/pdfhttp://hdl.handle.net/10362/116911eng2076-2607PURE: 29528830https://doi.org/10.3390/microorganisms8111651info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:59:48Zoai:run.unl.pt:10362/116911Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:43:22.261122Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
title |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
spellingShingle |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. David-Palma, Márcia Astaxanthin Fungal MAT genes Phaffia Phylogenomics Yeast taxonomy Microbiology Microbiology (medical) Virology |
title_short |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
title_full |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
title_fullStr |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
title_full_unstemmed |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
title_sort |
The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov. |
author |
David-Palma, Márcia |
author_facet |
David-Palma, Márcia Libkind, Diego Brito, Patrícia H. Silva, Margarida Bellora, Nicolás Coelho, Marco A. Heitman, Joseph Gonçalves, Paula Sampaio, José Paulo |
author_role |
author |
author2 |
Libkind, Diego Brito, Patrícia H. Silva, Margarida Bellora, Nicolás Coelho, Marco A. Heitman, Joseph Gonçalves, Paula Sampaio, José Paulo |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
UCIBIO - Applied Molecular Biosciences Unit DCV - Departamento de Ciências da Vida RUN |
dc.contributor.author.fl_str_mv |
David-Palma, Márcia Libkind, Diego Brito, Patrícia H. Silva, Margarida Bellora, Nicolás Coelho, Marco A. Heitman, Joseph Gonçalves, Paula Sampaio, José Paulo |
dc.subject.por.fl_str_mv |
Astaxanthin Fungal MAT genes Phaffia Phylogenomics Yeast taxonomy Microbiology Microbiology (medical) Virology |
topic |
Astaxanthin Fungal MAT genes Phaffia Phylogenomics Yeast taxonomy Microbiology Microbiology (medical) Virology |
description |
PTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16 |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-24 2020-10-24T00:00:00Z 2021-05-03T22:56:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/116911 |
url |
http://hdl.handle.net/10362/116911 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2076-2607 PURE: 29528830 https://doi.org/10.3390/microorganisms8111651 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
15 application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799138043343405056 |