The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.

Detalhes bibliográficos
Autor(a) principal: David-Palma, Márcia
Data de Publicação: 2020
Outros Autores: Libkind, Diego, Brito, Patrícia H., Silva, Margarida, Bellora, Nicolás, Coelho, Marco A., Heitman, Joseph, Gonçalves, Paula, Sampaio, José Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/116911
Resumo: PTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16
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spelling The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.AstaxanthinFungal MAT genesPhaffiaPhylogenomicsYeast taxonomyMicrobiologyMicrobiology (medical)VirologyPTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16Phaffia is an orange-colored basidiomycetous yeast genus of the order Cystofilobasidiales that contains a single species, P. rhodozyma. This species is the only fungus known to produce the economically relevant carotenoid astaxanthin. Although Phaffia was originally found in the Northern hemisphere, its diversity in the southern part of the globe has been shown to be much greater. Here we analyze the genomes of two Australasian lineages that are markedly distinct from P. rhodozyma. The two divergent lineages were investigated within a comprehensive phylogenomic study of representatives of the Cystofilobasidiales that supported the recognition of two novel Phaffia species, for which we propose the names of P. australis sp. nov. and P. tasmanica sp. nov. Comparative genomics and other analyses confirmed that the two new species have the typical Phaffia hallmark—the six genes necessary for the biosynthesis of astaxanthin could be retrieved from the draft genome sequences, and this carotenoid was detected in culture extracts. In addition, the organization of the mating-type (MAT) loci is similar to that of P. rhodozyma, with synteny throughout most regions. Moreover, cases of trans-specific polymorphism involving pheromone receptor genes and pheromone precursor proteins in the three Phaffia species, together with their shared homothallism, provide additional support for their classification in a single genus.UCIBIO - Applied Molecular Biosciences UnitDCV - Departamento de Ciências da VidaRUNDavid-Palma, MárciaLibkind, DiegoBrito, Patrícia H.Silva, MargaridaBellora, NicolásCoelho, Marco A.Heitman, JosephGonçalves, PaulaSampaio, José Paulo2021-05-03T22:56:08Z2020-10-242020-10-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article15application/pdfhttp://hdl.handle.net/10362/116911eng2076-2607PURE: 29528830https://doi.org/10.3390/microorganisms8111651info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:59:48Zoai:run.unl.pt:10362/116911Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:43:22.261122Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
title The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
spellingShingle The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
David-Palma, Márcia
Astaxanthin
Fungal MAT genes
Phaffia
Phylogenomics
Yeast taxonomy
Microbiology
Microbiology (medical)
Virology
title_short The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
title_full The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
title_fullStr The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
title_full_unstemmed The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
title_sort The untapped Australasian diversity of astaxanthin-producing yeasts with biotechnological potential—Phaffia Australis sp. nov. and Phaffia tasmanica sp. nov.
author David-Palma, Márcia
author_facet David-Palma, Márcia
Libkind, Diego
Brito, Patrícia H.
Silva, Margarida
Bellora, Nicolás
Coelho, Marco A.
Heitman, Joseph
Gonçalves, Paula
Sampaio, José Paulo
author_role author
author2 Libkind, Diego
Brito, Patrícia H.
Silva, Margarida
Bellora, Nicolás
Coelho, Marco A.
Heitman, Joseph
Gonçalves, Paula
Sampaio, José Paulo
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv UCIBIO - Applied Molecular Biosciences Unit
DCV - Departamento de Ciências da Vida
RUN
dc.contributor.author.fl_str_mv David-Palma, Márcia
Libkind, Diego
Brito, Patrícia H.
Silva, Margarida
Bellora, Nicolás
Coelho, Marco A.
Heitman, Joseph
Gonçalves, Paula
Sampaio, José Paulo
dc.subject.por.fl_str_mv Astaxanthin
Fungal MAT genes
Phaffia
Phylogenomics
Yeast taxonomy
Microbiology
Microbiology (medical)
Virology
topic Astaxanthin
Fungal MAT genes
Phaffia
Phylogenomics
Yeast taxonomy
Microbiology
Microbiology (medical)
Virology
description PTDC/BIA-MIC/30785/2017 UIDB/04378/2020 NIH/NIAID R37 MERIT Award AI39115-23 NIH/NIAID R01 AI50113-16
publishDate 2020
dc.date.none.fl_str_mv 2020-10-24
2020-10-24T00:00:00Z
2021-05-03T22:56:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/116911
url http://hdl.handle.net/10362/116911
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2076-2607
PURE: 29528830
https://doi.org/10.3390/microorganisms8111651
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 15
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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