The effect of growth factors on the osseointegration of dental implants

Detalhes bibliográficos
Autor(a) principal: Magalhães, Helena Margarida Assis
Data de Publicação: 2017
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/29516
Resumo: Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017
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spelling The effect of growth factors on the osseointegration of dental implantsImplantes dentáriosTeses de mestrado - 2017Domínio/Área Científica::Ciências Médicas::Medicina ClínicaTese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017Introduction: Dental implants have been an option of treatment commonly used in dentistry. Osseointegration is a measure of implant stability and can be enhanced by increasing the contact of bone to implant. Many strategies such as osteogenic coatings with growth factors have been studied in order to achieve it. Objective: To evaluate the effect of growth factors coating dental implants on the osseointegration. Methods: An electronic search was conducted in three databases such as PubMed, Evidence Based-Dentistry and Cochrane Library with the keywords “growth factors AND osseointegration AND dental implants”, “bone morphogenetic protein AND osseointegration AND dental implants”, “platelet derived growth factor AND osseointegration AND dental implants”, during November 2016 and May 2017. There were included in vivo studies that evaluated the effect of growth factor coated implants on maxillae or mandibular bone. Articles were limited to those published in English, Portuguese and Spanish. Results: Nine animal studies were analysed according to their results and surface modification. Five articles revealed a positive effect on the osseointegration, as the values obtained were higher when compared to uncoated groups. The lack of standardization makes the comparison of studies and their analysis difficult and therefore it is not possible to conclude the real action of these proteins on the formation of bone. Conclusions: New therapies have been developed to increase the contact between bone and implant and its stability by altering their surfaces. Implants coated with growth factors seem to be a promising alternative to increase the rate of long term successful implant surgeries and needs to be assessed in order to become an available option for future treatments. It is crucial the creation of prospective studies to extrapolate these results to a human model.Caramês, João, 1962-Francisco, HelenaRepositório da Universidade de LisboaMagalhães, Helena Margarida Assis2017-10-31T16:36:32Z201720172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10451/29516TID:201737213enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:21:38Zoai:repositorio.ul.pt:10451/29516Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:45:23.164879Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The effect of growth factors on the osseointegration of dental implants
title The effect of growth factors on the osseointegration of dental implants
spellingShingle The effect of growth factors on the osseointegration of dental implants
Magalhães, Helena Margarida Assis
Implantes dentários
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
title_short The effect of growth factors on the osseointegration of dental implants
title_full The effect of growth factors on the osseointegration of dental implants
title_fullStr The effect of growth factors on the osseointegration of dental implants
title_full_unstemmed The effect of growth factors on the osseointegration of dental implants
title_sort The effect of growth factors on the osseointegration of dental implants
author Magalhães, Helena Margarida Assis
author_facet Magalhães, Helena Margarida Assis
author_role author
dc.contributor.none.fl_str_mv Caramês, João, 1962-
Francisco, Helena
Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Magalhães, Helena Margarida Assis
dc.subject.por.fl_str_mv Implantes dentários
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
topic Implantes dentários
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
description Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017
publishDate 2017
dc.date.none.fl_str_mv 2017-10-31T16:36:32Z
2017
2017
2017-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/29516
TID:201737213
url http://hdl.handle.net/10451/29516
identifier_str_mv TID:201737213
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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