Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors

Detalhes bibliográficos
Autor(a) principal: Silva, Ana João
Data de Publicação: 2023
Outros Autores: Guilherme Pereira, José, Cadavez, Hugo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.gazetamedica.pt/index.php/gazeta/article/view/700
Resumo: Penile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer.
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spelling Penile Neoplasm: Diagnosis Masked by SGLT2 InhibitorsNeoplasia Peniana: Diagnóstico Mascarado por Inibidores do SGLT2Infeções do Sistema Genital/etiologiaInibidores do Transportador 2 de Sódio-Glicose/efeitos adversosNeoplasias Penianas/diagnósticoPenile Neoplasms/diagnosisReproductive Tract Infections/etiologySodium-Glucose Transporter 2 Inhibitors/adverse effectsPenile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer.O cancro do pénis é uma neoplasia rara que se pode apresentar com uma variada gama de sintomas. Quando diagnosticado precocemente tem um excelente prognóstico, contudo, este piora dramaticamente na presença de metástases. Doente de 69 anos, sexo masculino, com antecedentes pessoais de diabetes mellitus. Após prescrição de empagliflozina recorre por lesão eritematosa no prepúcio. Foi medicado progressivamente com clotrimazol creme, valaciclovir, azitromicina, timidazol, fluconazol, amoxicilina + ácido clavulânico e hidrocortisona sem resolução do quadro. Diagnosticado com carcinoma epidermoide do pénis após biópsia em consulta de Dermatologia. Trata-se de um caso de cancro do pénis com sintomatologia inespecífica num doente com fatores de risco para infeções genitais, dificultando a suspeição clínica e promovendo a adoção de medidas dirigidas ao tratamento da infeção genital. O papel do médico de família é fundamental para uma referenciação precoce dos doentes com clínica sugestiva de cancro do pénis.CUF Academic Center2023-09-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.gazetamedica.pt/index.php/gazeta/article/view/700Gazeta Médica; Ahead of PrintGazeta Médica; Ahead of Print2184-06282183-8135reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.gazetamedica.pt/index.php/gazeta/article/view/700https://www.gazetamedica.pt/index.php/gazeta/article/view/700/438Copyright (c) 2023 Gazeta Médicahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessSilva, Ana JoãoGuilherme Pereira, JoséCadavez, Hugo2023-09-09T04:49:24ZPortal AgregadorONG
dc.title.none.fl_str_mv Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
Neoplasia Peniana: Diagnóstico Mascarado por Inibidores do SGLT2
title Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
spellingShingle Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
Silva, Ana João
Infeções do Sistema Genital/etiologia
Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos
Neoplasias Penianas/diagnóstico
Penile Neoplasms/diagnosis
Reproductive Tract Infections/etiology
Sodium-Glucose Transporter 2 Inhibitors/adverse effects
title_short Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
title_full Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
title_fullStr Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
title_full_unstemmed Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
title_sort Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
author Silva, Ana João
author_facet Silva, Ana João
Guilherme Pereira, José
Cadavez, Hugo
author_role author
author2 Guilherme Pereira, José
Cadavez, Hugo
author2_role author
author
dc.contributor.author.fl_str_mv Silva, Ana João
Guilherme Pereira, José
Cadavez, Hugo
dc.subject.por.fl_str_mv Infeções do Sistema Genital/etiologia
Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos
Neoplasias Penianas/diagnóstico
Penile Neoplasms/diagnosis
Reproductive Tract Infections/etiology
Sodium-Glucose Transporter 2 Inhibitors/adverse effects
topic Infeções do Sistema Genital/etiologia
Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos
Neoplasias Penianas/diagnóstico
Penile Neoplasms/diagnosis
Reproductive Tract Infections/etiology
Sodium-Glucose Transporter 2 Inhibitors/adverse effects
description Penile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-06
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.gazetamedica.pt/index.php/gazeta/article/view/700
url https://www.gazetamedica.pt/index.php/gazeta/article/view/700
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.gazetamedica.pt/index.php/gazeta/article/view/700
https://www.gazetamedica.pt/index.php/gazeta/article/view/700/438
dc.rights.driver.fl_str_mv Copyright (c) 2023 Gazeta Médica
http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Gazeta Médica
http://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv CUF Academic Center
publisher.none.fl_str_mv CUF Academic Center
dc.source.none.fl_str_mv Gazeta Médica; Ahead of Print
Gazeta Médica; Ahead of Print
2184-0628
2183-8135
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.mail.fl_str_mv
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