Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.gazetamedica.pt/index.php/gazeta/article/view/700 |
Resumo: | Penile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer. |
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Penile Neoplasm: Diagnosis Masked by SGLT2 InhibitorsNeoplasia Peniana: Diagnóstico Mascarado por Inibidores do SGLT2Infeções do Sistema Genital/etiologiaInibidores do Transportador 2 de Sódio-Glicose/efeitos adversosNeoplasias Penianas/diagnósticoPenile Neoplasms/diagnosisReproductive Tract Infections/etiologySodium-Glucose Transporter 2 Inhibitors/adverse effectsPenile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer.O cancro do pénis é uma neoplasia rara que se pode apresentar com uma variada gama de sintomas. Quando diagnosticado precocemente tem um excelente prognóstico, contudo, este piora dramaticamente na presença de metástases. Doente de 69 anos, sexo masculino, com antecedentes pessoais de diabetes mellitus. Após prescrição de empagliflozina recorre por lesão eritematosa no prepúcio. Foi medicado progressivamente com clotrimazol creme, valaciclovir, azitromicina, timidazol, fluconazol, amoxicilina + ácido clavulânico e hidrocortisona sem resolução do quadro. Diagnosticado com carcinoma epidermoide do pénis após biópsia em consulta de Dermatologia. Trata-se de um caso de cancro do pénis com sintomatologia inespecífica num doente com fatores de risco para infeções genitais, dificultando a suspeição clínica e promovendo a adoção de medidas dirigidas ao tratamento da infeção genital. O papel do médico de família é fundamental para uma referenciação precoce dos doentes com clínica sugestiva de cancro do pénis.CUF Academic Center2023-09-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.gazetamedica.pt/index.php/gazeta/article/view/700Gazeta Médica; Ahead of PrintGazeta Médica; Ahead of Print2184-06282183-8135reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.gazetamedica.pt/index.php/gazeta/article/view/700https://www.gazetamedica.pt/index.php/gazeta/article/view/700/438Copyright (c) 2023 Gazeta Médicahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessSilva, Ana JoãoGuilherme Pereira, JoséCadavez, Hugo2023-09-09T04:49:24ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors Neoplasia Peniana: Diagnóstico Mascarado por Inibidores do SGLT2 |
title |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
spellingShingle |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors Silva, Ana João Infeções do Sistema Genital/etiologia Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos Neoplasias Penianas/diagnóstico Penile Neoplasms/diagnosis Reproductive Tract Infections/etiology Sodium-Glucose Transporter 2 Inhibitors/adverse effects |
title_short |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
title_full |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
title_fullStr |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
title_full_unstemmed |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
title_sort |
Penile Neoplasm: Diagnosis Masked by SGLT2 Inhibitors |
author |
Silva, Ana João |
author_facet |
Silva, Ana João Guilherme Pereira, José Cadavez, Hugo |
author_role |
author |
author2 |
Guilherme Pereira, José Cadavez, Hugo |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Silva, Ana João Guilherme Pereira, José Cadavez, Hugo |
dc.subject.por.fl_str_mv |
Infeções do Sistema Genital/etiologia Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos Neoplasias Penianas/diagnóstico Penile Neoplasms/diagnosis Reproductive Tract Infections/etiology Sodium-Glucose Transporter 2 Inhibitors/adverse effects |
topic |
Infeções do Sistema Genital/etiologia Inibidores do Transportador 2 de Sódio-Glicose/efeitos adversos Neoplasias Penianas/diagnóstico Penile Neoplasms/diagnosis Reproductive Tract Infections/etiology Sodium-Glucose Transporter 2 Inhibitors/adverse effects |
description |
Penile cancer is a rare neoplasm that can present with a wide range of symptoms. When diagnosed early, it has an excellent prognosis, however, it worsens dramatically in the presence of metastases. A 69-year-old male patient with a personal history of diabetes mellitus. After prescription of empagliflozin, the patient develops an erythematous lesion in the foreskin. He was progressively medicated with clotrimazole cream, valaciclovir, azithromycin, tinidazole, fluconazole, amoxicillin + clavulanic acid and hydrocortisone without improvement. Diagnosed with squamous cell carcinoma of the penis after biopsy in a Dermatology consultation. This is a case of penile cancer with non-specific symptoms in a patient with risk factors for genital infections, making clinical suspicion difficult and promoting the adoption of measures aimed at the treatment of genital infection. The role of the family doctor is essential for an early referral of patients with clinical signs suggestive of penile cancer. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-06 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.gazetamedica.pt/index.php/gazeta/article/view/700 |
url |
https://www.gazetamedica.pt/index.php/gazeta/article/view/700 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.gazetamedica.pt/index.php/gazeta/article/view/700 https://www.gazetamedica.pt/index.php/gazeta/article/view/700/438 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Gazeta Médica http://creativecommons.org/licenses/by-nc-nd/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Gazeta Médica http://creativecommons.org/licenses/by-nc-nd/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
CUF Academic Center |
publisher.none.fl_str_mv |
CUF Academic Center |
dc.source.none.fl_str_mv |
Gazeta Médica; Ahead of Print Gazeta Médica; Ahead of Print 2184-0628 2183-8135 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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