Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging

Detalhes bibliográficos
Autor(a) principal: Prezas, Pedro R.
Data de Publicação: 2023
Outros Autores: Soares, Manuel J., Borges, João P., Silva, Jorge C., Oliveira, Filipe J., Graça, Manuel Pedro F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/154888
Resumo: Funding Information: This research was funded by FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2022 of the Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication—i3N. Publisher Copyright: © 2023 by the authors.
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spelling Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Chargingatmospheric plasma spraybioactivitycorona charginghydroxyapatite coatingsnon-contact electrical chargingChemical Engineering(all)Materials Science(all)Funding Information: This research was funded by FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2022 of the Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication—i3N. Publisher Copyright: © 2023 by the authors.Atmospheric plasma spray (APS) remains the only certified industrial process to produce hydroxyapatite (Hap) coatings on orthopaedic and dental implants intended for commercialization. Despite the established clinical success of Hap-coated implants, such as hip and knee arthroplasties, a concern is being raised regarding the failure and revision rates in younger patients, which are increasing rapidly worldwide. The lifetime risk of replacement for patients in the 50–60 age interval is about 35%, which is significantly higher than 5% for patients aged 70 or older. Improved implants targeted at younger patients are a necessity that experts have been alerted to. One approach is to enhance their bioactivity. For this purpose, the method with the most outstanding biological results is the electrical polarization of Hap, which remarkably accelerates implant osteointegration. There is, however, the technical challenge of charging the coatings. Although this is straightforward on bulk samples with planar faces, it is not easy on coatings, and there are several problems regarding the application of electrodes. To the best of our knowledge, this study demonstrates, for the first time, the electrical charging of APS Hap coatings using a non-contact, electrode-free method: corona charging. Bioactivity enhancement is observed, establishing the promising potential of corona charging in orthopedics and dental implantology. It is found that the coatings can store charge at the surface and bulk levels up to high surface potentials (>1000 V). The biological in vitro results show higher Ca2+ and P5+ intakes in charged coatings compared to non-charged coatings. Moreover, a higher osteoblastic cellular proliferation is promoted in the charged coatings, indicating the promising potential of corona-charged coatings when applied in orthopedics and dental implantology.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)RUNPrezas, Pedro R.Soares, Manuel J.Borges, João P.Silva, Jorge C.Oliveira, Filipe J.Graça, Manuel Pedro F.2023-07-05T22:18:04Z2023-03-152023-03-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article15application/pdfhttp://hdl.handle.net/10362/154888eng2079-4991PURE: 65372494https://doi.org/10.3390/nano13061058info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:37:20Zoai:run.unl.pt:10362/154888Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:55:50.185425Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
title Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
spellingShingle Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
Prezas, Pedro R.
atmospheric plasma spray
bioactivity
corona charging
hydroxyapatite coatings
non-contact electrical charging
Chemical Engineering(all)
Materials Science(all)
title_short Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
title_full Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
title_fullStr Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
title_full_unstemmed Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
title_sort Bioactivity Enhancement of Plasma-Sprayed Hydroxyapatite Coatings through Non-Contact Corona Electrical Charging
author Prezas, Pedro R.
author_facet Prezas, Pedro R.
Soares, Manuel J.
Borges, João P.
Silva, Jorge C.
Oliveira, Filipe J.
Graça, Manuel Pedro F.
author_role author
author2 Soares, Manuel J.
Borges, João P.
Silva, Jorge C.
Oliveira, Filipe J.
Graça, Manuel Pedro F.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
RUN
dc.contributor.author.fl_str_mv Prezas, Pedro R.
Soares, Manuel J.
Borges, João P.
Silva, Jorge C.
Oliveira, Filipe J.
Graça, Manuel Pedro F.
dc.subject.por.fl_str_mv atmospheric plasma spray
bioactivity
corona charging
hydroxyapatite coatings
non-contact electrical charging
Chemical Engineering(all)
Materials Science(all)
topic atmospheric plasma spray
bioactivity
corona charging
hydroxyapatite coatings
non-contact electrical charging
Chemical Engineering(all)
Materials Science(all)
description Funding Information: This research was funded by FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LIS-BOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2022 of the Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication—i3N. Publisher Copyright: © 2023 by the authors.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-05T22:18:04Z
2023-03-15
2023-03-15T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/154888
url http://hdl.handle.net/10362/154888
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-4991
PURE: 65372494
https://doi.org/10.3390/nano13061058
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 15
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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