Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/3453 |
Resumo: | The gut microbiota plays a main role in the maintenance of host's health. Exposure to different conditions in early life contributes to distinct 'pioneer' bacterial communities in the intestine, which shape the newborn infant development. Newborn infants with congenital malformations of the gastrointestinal tract (CMGIT), necrotising enterocolitis (NEC) and spontaneous intestinal perforation (SIP) commonly require abdominal surgery and enterostomy. The knowledge about the colonisation of these newborns' intestine by microorganisms is scarce. This protocol is designed to explore the microbial colonisation over time of the proximal intestinal remnant in newborn infants who underwent surgery for CMGIT, NEC or SIP and require enterostomy. |
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Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study ProtocolCongenital MalformationsDysbiosisEnterostomyMicrobiotaNecrotizing EnterocolitisInfant, NewbornHDE CINVHDE UCI NEOThe gut microbiota plays a main role in the maintenance of host's health. Exposure to different conditions in early life contributes to distinct 'pioneer' bacterial communities in the intestine, which shape the newborn infant development. Newborn infants with congenital malformations of the gastrointestinal tract (CMGIT), necrotising enterocolitis (NEC) and spontaneous intestinal perforation (SIP) commonly require abdominal surgery and enterostomy. The knowledge about the colonisation of these newborns' intestine by microorganisms is scarce. This protocol is designed to explore the microbial colonisation over time of the proximal intestinal remnant in newborn infants who underwent surgery for CMGIT, NEC or SIP and require enterostomy.BMJ Publishing GroupRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEBarreiros Mota, IMarques, CFaria, CNeto, MTCordeiro-Ferreira, GVirella, DPita, APereira-da-Silva, LCalhau, C2020-05-22T08:51:20Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3453engBMJ Open . 2019 Nov 24;9(11):e02891610.1136/bmjopen-2019-028916info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:43:05Zoai:repositorio.chlc.min-saude.pt:10400.17/3453Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:45.996764Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
title |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
spellingShingle |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol Barreiros Mota, I Congenital Malformations Dysbiosis Enterostomy Microbiota Necrotizing Enterocolitis Infant, Newborn HDE CINV HDE UCI NEO |
title_short |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
title_full |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
title_fullStr |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
title_full_unstemmed |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
title_sort |
Colonisation of the Proximal Intestinal Remnant in Newborn Infants with Enterostomy: a Longitudinal Study Protocol |
author |
Barreiros Mota, I |
author_facet |
Barreiros Mota, I Marques, C Faria, C Neto, MT Cordeiro-Ferreira, G Virella, D Pita, A Pereira-da-Silva, L Calhau, C |
author_role |
author |
author2 |
Marques, C Faria, C Neto, MT Cordeiro-Ferreira, G Virella, D Pita, A Pereira-da-Silva, L Calhau, C |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Barreiros Mota, I Marques, C Faria, C Neto, MT Cordeiro-Ferreira, G Virella, D Pita, A Pereira-da-Silva, L Calhau, C |
dc.subject.por.fl_str_mv |
Congenital Malformations Dysbiosis Enterostomy Microbiota Necrotizing Enterocolitis Infant, Newborn HDE CINV HDE UCI NEO |
topic |
Congenital Malformations Dysbiosis Enterostomy Microbiota Necrotizing Enterocolitis Infant, Newborn HDE CINV HDE UCI NEO |
description |
The gut microbiota plays a main role in the maintenance of host's health. Exposure to different conditions in early life contributes to distinct 'pioneer' bacterial communities in the intestine, which shape the newborn infant development. Newborn infants with congenital malformations of the gastrointestinal tract (CMGIT), necrotising enterocolitis (NEC) and spontaneous intestinal perforation (SIP) commonly require abdominal surgery and enterostomy. The knowledge about the colonisation of these newborns' intestine by microorganisms is scarce. This protocol is designed to explore the microbial colonisation over time of the proximal intestinal remnant in newborn infants who underwent surgery for CMGIT, NEC or SIP and require enterostomy. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z 2020-05-22T08:51:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/3453 |
url |
http://hdl.handle.net/10400.17/3453 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMJ Open . 2019 Nov 24;9(11):e028916 10.1136/bmjopen-2019-028916 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMJ Publishing Group |
publisher.none.fl_str_mv |
BMJ Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1817554567137591296 |