Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians

Detalhes bibliográficos
Autor(a) principal: Almeida, Daniela
Data de Publicação: 2022
Outros Autores: Santos-Silva, Sérgio, Pereira, Maria Aires, Santos, Carla, Mega, Cristina, Coelho, Catarina, Nóbrega, Carmen, Esteves, Fernando, Cruz, Rita, Vala, Helena, Mesquita, João R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/147808
Resumo: Funding Information: This study was supported by FCT—Foundation for Science and Technology, I.P., through research grant PTDC/CVT-CVT/0228/2020 and by funds from the Global Health and Tropical Medicine (GHTM, UID/04413/2020), the Research Centre for Endogenous Resource Valorization (VALORIZA, UIDB/05064/2020), the Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB, UIDB/04033/2020) and the Centre for Natural Resources, Environment and Society (CERNAS, UIDB/00681/2020). This work was supported by national funds, through Fundação para a Ciência e Tecnologia (FCT, Portuguese Foundation for Science and Technology), under projects UIDB/04750/2020 and LA/P/0064/2020. Publisher Copyright: © 2022 by the authors.
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spelling Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese VeterinariansA Matched Case–Control StudyIgG antibodiesPortugalToxoplasma gondiiveterinary practitionersQR180 ImmunologyRA0421 Public health. Hygiene. Preventive MedicineImmunology and AllergyMolecular BiologyImmunology and Microbiology(all)Microbiology (medical)Infectious Diseasesveterinary(all)SDG 3 - Good Health and Well-beingFunding Information: This study was supported by FCT—Foundation for Science and Technology, I.P., through research grant PTDC/CVT-CVT/0228/2020 and by funds from the Global Health and Tropical Medicine (GHTM, UID/04413/2020), the Research Centre for Endogenous Resource Valorization (VALORIZA, UIDB/05064/2020), the Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB, UIDB/04033/2020) and the Centre for Natural Resources, Environment and Society (CERNAS, UIDB/00681/2020). This work was supported by national funds, through Fundação para a Ciência e Tecnologia (FCT, Portuguese Foundation for Science and Technology), under projects UIDB/04750/2020 and LA/P/0064/2020. Publisher Copyright: © 2022 by the authors.(1) Background: Toxoplasma gondii is a widespread zoonotic agent that greatly impacts Public Health, being responsible for one of the most important parasitic zoonosis worldwide. T. gondii has a heteroxenous life cycle, with cats being the definitive hosts and all warm-blooded animals, including humans, being intermediate hosts. Veterinary practitioners (VP) may be at a higher risk than the general population for T. gondii infection, as they have direct and daily contact with many animal species. The aim of the present study was to ascertain if VP were more likely to be anti-T. gondii IgG seropositive than the general population, as well as to understand if age, accidents with blood-contaminated sharps (cross-blood contamination), gender, working years, and geographic regions play a role as risk factors for T. gondii infection. For this purpose, a case–control study using archived samples was performed. (2) Methods: A total of 350 veterinary practitioners were tested using a commercial semiquantitative enzyme immunoassay for anti-T. gondii IgG. From the general population, 175 anonymous volunteers (matched with cases by region, age, and gender) were studied for anti-T. gondii IgG. (3) Results: There was no statistical difference found between the presence of anti-T. gondii IgG in practitioners (26%; CI = 21.40–30.60%) and the general population (33.14%; CI = 26.17–40.12%) (p = 0.108). Univariate and multivariate analysis showed that only age (older groups) was found to be associated with a higher prevalence of anti-T. gondii IgG, with significant p values (p < 0.05) for both univariate and multivariate analysis. (4) Conclusions: To the best of our knowledge, this is the first case–control study fully focused on the prevalence of anti-T. gondii IgG in VP in Portugal, showing that there was no significant risk for T. gondii infection in veterinarians exposed daily and repeatedly to different species of animals.Instituto de Higiene e Medicina Tropical (IHMT)Universidade NOVA de LisboaVector borne diseases and pathogens (VBD)RUNAlmeida, DanielaSantos-Silva, SérgioPereira, Maria AiresSantos, CarlaMega, CristinaCoelho, CatarinaNóbrega, CarmenEsteves, FernandoCruz, RitaVala, HelenaMesquita, João R.2023-01-18T22:16:59Z2022-102022-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/147808eng2076-0817PURE: 49791375https://doi.org/10.3390/pathogens11101217info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:29:03Zoai:run.unl.pt:10362/147808Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:05.256327Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
A Matched Case–Control Study
title Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
spellingShingle Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
Almeida, Daniela
IgG antibodies
Portugal
Toxoplasma gondii
veterinary practitioners
QR180 Immunology
RA0421 Public health. Hygiene. Preventive Medicine
Immunology and Allergy
Molecular Biology
Immunology and Microbiology(all)
Microbiology (medical)
Infectious Diseases
veterinary(all)
SDG 3 - Good Health and Well-being
title_short Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
title_full Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
title_fullStr Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
title_full_unstemmed Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
title_sort Prevalence of Toxoplasma gondii Antibodies and Risk Factor Investigation in Portuguese Veterinarians
author Almeida, Daniela
author_facet Almeida, Daniela
Santos-Silva, Sérgio
Pereira, Maria Aires
Santos, Carla
Mega, Cristina
Coelho, Catarina
Nóbrega, Carmen
Esteves, Fernando
Cruz, Rita
Vala, Helena
Mesquita, João R.
author_role author
author2 Santos-Silva, Sérgio
Pereira, Maria Aires
Santos, Carla
Mega, Cristina
Coelho, Catarina
Nóbrega, Carmen
Esteves, Fernando
Cruz, Rita
Vala, Helena
Mesquita, João R.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
Universidade NOVA de Lisboa
Vector borne diseases and pathogens (VBD)
RUN
dc.contributor.author.fl_str_mv Almeida, Daniela
Santos-Silva, Sérgio
Pereira, Maria Aires
Santos, Carla
Mega, Cristina
Coelho, Catarina
Nóbrega, Carmen
Esteves, Fernando
Cruz, Rita
Vala, Helena
Mesquita, João R.
dc.subject.por.fl_str_mv IgG antibodies
Portugal
Toxoplasma gondii
veterinary practitioners
QR180 Immunology
RA0421 Public health. Hygiene. Preventive Medicine
Immunology and Allergy
Molecular Biology
Immunology and Microbiology(all)
Microbiology (medical)
Infectious Diseases
veterinary(all)
SDG 3 - Good Health and Well-being
topic IgG antibodies
Portugal
Toxoplasma gondii
veterinary practitioners
QR180 Immunology
RA0421 Public health. Hygiene. Preventive Medicine
Immunology and Allergy
Molecular Biology
Immunology and Microbiology(all)
Microbiology (medical)
Infectious Diseases
veterinary(all)
SDG 3 - Good Health and Well-being
description Funding Information: This study was supported by FCT—Foundation for Science and Technology, I.P., through research grant PTDC/CVT-CVT/0228/2020 and by funds from the Global Health and Tropical Medicine (GHTM, UID/04413/2020), the Research Centre for Endogenous Resource Valorization (VALORIZA, UIDB/05064/2020), the Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB, UIDB/04033/2020) and the Centre for Natural Resources, Environment and Society (CERNAS, UIDB/00681/2020). This work was supported by national funds, through Fundação para a Ciência e Tecnologia (FCT, Portuguese Foundation for Science and Technology), under projects UIDB/04750/2020 and LA/P/0064/2020. Publisher Copyright: © 2022 by the authors.
publishDate 2022
dc.date.none.fl_str_mv 2022-10
2022-10-01T00:00:00Z
2023-01-18T22:16:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/147808
url http://hdl.handle.net/10362/147808
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2076-0817
PURE: 49791375
https://doi.org/10.3390/pathogens11101217
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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