Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/38239 |
Resumo: | INTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...) |
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Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approachesINTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...)(undefined)Swiss Society for BiomaterialsUniversidade do MinhoPedrosa, Sílvia SantosGama, F. M.2010-08-242010-08-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/38239engPedrosa, S.; Gama, F. M., Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches. European Cells and Materials, 20(Suppl. 3), 224-224, 20101473-2262http://www.ecmjournal.org/info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:26:37Zoai:repositorium.sdum.uminho.pt:1822/38239Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:21:04.787537Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
title |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
spellingShingle |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches Pedrosa, Sílvia Santos |
title_short |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
title_full |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
title_fullStr |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
title_full_unstemmed |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
title_sort |
Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches |
author |
Pedrosa, Sílvia Santos |
author_facet |
Pedrosa, Sílvia Santos Gama, F. M. |
author_role |
author |
author2 |
Gama, F. M. |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Pedrosa, Sílvia Santos Gama, F. M. |
description |
INTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...) |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-08-24 2010-08-24T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/38239 |
url |
http://hdl.handle.net/1822/38239 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Pedrosa, S.; Gama, F. M., Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches. European Cells and Materials, 20(Suppl. 3), 224-224, 2010 1473-2262 http://www.ecmjournal.org/ |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Swiss Society for Biomaterials |
publisher.none.fl_str_mv |
Swiss Society for Biomaterials |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132676273209344 |