Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches

Detalhes bibliográficos
Autor(a) principal: Pedrosa, Sílvia Santos
Data de Publicação: 2010
Outros Autores: Gama, F. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/38239
Resumo: INTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...)
id RCAP_f5cc8662c48eb63dabd218461ed8eca8
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/38239
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approachesINTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...)(undefined)Swiss Society for BiomaterialsUniversidade do MinhoPedrosa, Sílvia SantosGama, F. M.2010-08-242010-08-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/38239engPedrosa, S.; Gama, F. M., Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches. European Cells and Materials, 20(Suppl. 3), 224-224, 20101473-2262http://www.ecmjournal.org/info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:26:37Zoai:repositorium.sdum.uminho.pt:1822/38239Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:21:04.787537Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
title Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
spellingShingle Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
Pedrosa, Sílvia Santos
title_short Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
title_full Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
title_fullStr Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
title_full_unstemmed Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
title_sort Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches
author Pedrosa, Sílvia Santos
author_facet Pedrosa, Sílvia Santos
Gama, F. M.
author_role author
author2 Gama, F. M.
author2_role author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Pedrosa, Sílvia Santos
Gama, F. M.
description INTRODUCTION: Natural polyssacharides, such as hyaluronic acid (HyA) have been widely used for biomedical and pharmaceutical applications. Hya has multiple functional groups available for chemical conjugation that can convert HyA into nano-sized carriers. We prepared self-assembled HyA nanoparticles by two different chemical derivatization techniques and used two different molecular weights HyA. Our aim was to compare these two techniques and evaluate the influence of molecular weight in the properties of HyA nanoparticles. (...)
publishDate 2010
dc.date.none.fl_str_mv 2010-08-24
2010-08-24T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/38239
url http://hdl.handle.net/1822/38239
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pedrosa, S.; Gama, F. M., Self-assembled hyaluronic acid nanoparticles: effect of molecular weight and two different chemical approaches. European Cells and Materials, 20(Suppl. 3), 224-224, 2010
1473-2262
http://www.ecmjournal.org/
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Swiss Society for Biomaterials
publisher.none.fl_str_mv Swiss Society for Biomaterials
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132676273209344