Editorial

Detalhes bibliográficos
Autor(a) principal: Videira, Paula Alexandra
Data de Publicação: 2022
Outros Autores: Borghesi, Marco, Singer, Eric A.
Tipo de documento: Outros
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/143419
Resumo: project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy - i4HB.
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spelling EditorialBiomarkers in Genitourinary Cancers, Volume Ibiomarkersbladder cacnergenitourinary cancerprostate cancerrenal cancerOncologyCancer ResearchSDG 3 - Good Health and Well-beingproject LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy - i4HB.Genitourinary cancers are known as significant causes of mortality worldwide. This heterogeneous group includes, among others, the most common cancer in men, prostate cancer, the most common form of kidney cancer, renal cell carcinoma (RCC), and the 10th most common cancer, bladder cancer. These entities present biological diversity with various histological subtypes and a poor prognosis when metastatic. There has been considerable progress in treating patients with genitourinary cancers due to the improved understanding of their pathological mechanisms and the identification of meaningful biomarkers. The treatment progress has led to a fundamental paradigm shift in treatments. For example, our current understanding of the immunogenicity of these tumours has improved tremendously. Thanks to that, today, immunotherapy is a reliable strategy to improve the outcomes of patients with metastatic urothelial carcinoma, renal cell carcinoma, and prostate cancer. However, there is still a critical need to enrich our understanding of additional molecular mechanisms. Along with the mechanisms, there is an urgent requirement to identify novel biomarkers to progress the diagnosis and prognosis of genitourinary cancers and their treatment. Biomarkers have become a significant focus of research, primarily on how they can help predict response to systemic therapy, identify treatment resistance, and avoid toxicities. Biomarkers that reveal the mutated tumour suppressor genes, the altered signalling pathways and the aberrantly expressed molecules help select potentially responsive patients to a given therapy. In this way, biomarkers improve outcomes and reduce costs related to ineffective treatments, and, most importantly, they significantly upsurge patients’ quality of life. This Research Topic named Biomarkers in Genitourinary Cancers includes an interesting and up to date palette of publications from prominent research and clinical groups focused on identifying significant and emerging prognostic and predictive biomarkers. These biomarkers encompass non-coding RNA, serum proteins, gene expression, and glycans, among other entities identified in patients’ cohorts, samples and in the increasing number of public databases.DCV - Departamento de Ciências da VidaUCIBIO - Applied Molecular Biosciences UnitRUNVideira, Paula AlexandraBorghesi, MarcoSinger, Eric A.2022-09-01T22:31:00Z2022-07-082022-07-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/other3application/pdfhttp://hdl.handle.net/10362/143419eng2234-943XPURE: 45753671https://doi.org/10.3389/fonc.2022.965294info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:04:47Zoai:run.unl.pt:10362/143419Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:04:47Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Editorial
Biomarkers in Genitourinary Cancers, Volume I
title Editorial
spellingShingle Editorial
Videira, Paula Alexandra
biomarkers
bladder cacner
genitourinary cancer
prostate cancer
renal cancer
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
title_short Editorial
title_full Editorial
title_fullStr Editorial
title_full_unstemmed Editorial
title_sort Editorial
author Videira, Paula Alexandra
author_facet Videira, Paula Alexandra
Borghesi, Marco
Singer, Eric A.
author_role author
author2 Borghesi, Marco
Singer, Eric A.
author2_role author
author
dc.contributor.none.fl_str_mv DCV - Departamento de Ciências da Vida
UCIBIO - Applied Molecular Biosciences Unit
RUN
dc.contributor.author.fl_str_mv Videira, Paula Alexandra
Borghesi, Marco
Singer, Eric A.
dc.subject.por.fl_str_mv biomarkers
bladder cacner
genitourinary cancer
prostate cancer
renal cancer
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
topic biomarkers
bladder cacner
genitourinary cancer
prostate cancer
renal cancer
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
description project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy - i4HB.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-01T22:31:00Z
2022-07-08
2022-07-08T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/143419
url http://hdl.handle.net/10362/143419
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2234-943X
PURE: 45753671
https://doi.org/10.3389/fonc.2022.965294
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 3
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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