Osteometabolic changes in patients under antineoplastic treatment: scoping review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Revista Ciências em Saúde |
Texto Completo: | https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442 |
Resumo: | Objective: To summarize the main evidence regarding osteometabolic changes in patients undergoing antineoplastic treatment. Methods: This is a scoping review, following the methodology of the Joanna Briggs Institute, using PubMed/MedLine, Cochrane Library, LILACS, The British Library, and Google Scholar. This review is registered in the Open Science Framework. Results: Many antineoplastics affect bone architecture by reducing its density, such as selective estrogen receptor modulators, aromatase inhibitors, androgen deprivation therapy, and glucocorticoids. To avoid such outcomes, treatment and prevention can be achieved by calcium and vitamin D supplementation, physical exercise, use of bisphosphonates, denosumab, and selective estrogen receptor modulators. Conclusion: people at a higher risk of developing cancer also have a higher risk of osteopenia and osteoporosis when the process is already established and undergoing antineoplastic treatment because of the grouping of risk factors. The need for bone densitometry in patients undergoing cancer treatment to prevent and promote bone health in these patients is evident, in addition to more research with a high level of evidence to support such use. |
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Osteometabolic changes in patients under antineoplastic treatment: scoping reviewAlterações osteometabólicas em pacientes em tratamento antineoplásico: revisão de escopoAntineoplasticsBonesChemotherapyMetabolic bone diseasesOncologyAntineoplásicosDoenças ósseas metabólicasOncologiaOssosQuimioterapiaObjective: To summarize the main evidence regarding osteometabolic changes in patients undergoing antineoplastic treatment. Methods: This is a scoping review, following the methodology of the Joanna Briggs Institute, using PubMed/MedLine, Cochrane Library, LILACS, The British Library, and Google Scholar. This review is registered in the Open Science Framework. Results: Many antineoplastics affect bone architecture by reducing its density, such as selective estrogen receptor modulators, aromatase inhibitors, androgen deprivation therapy, and glucocorticoids. To avoid such outcomes, treatment and prevention can be achieved by calcium and vitamin D supplementation, physical exercise, use of bisphosphonates, denosumab, and selective estrogen receptor modulators. Conclusion: people at a higher risk of developing cancer also have a higher risk of osteopenia and osteoporosis when the process is already established and undergoing antineoplastic treatment because of the grouping of risk factors. The need for bone densitometry in patients undergoing cancer treatment to prevent and promote bone health in these patients is evident, in addition to more research with a high level of evidence to support such use.Objetivo: sintetizar as principais evidências acerca das alterações osteometabólicas presentes nos pacientes em tratamento antineoplásico. Métodos: trata-se de uma revisão de escopo, seguindo a metodologia do Instituto Joanna Briggs, nas bases de dados PubMed/MedLine, Cochrane Library, LILACS, The British Library e Google Scholar. A revisão está protocolada no Open Science Framework. Resultados: muitos antineoplásicos possuem efeito na arquitetura óssea, reduzindo sua densidade, tais como moduladores seletivos de receptores de estrogênio, inibidores da aromatase, terapia de privação androgênica, e glicocorticoides. Para evitar tais desfechos, o tratamento e prevenção podem ser realizados pela suplementação de cálcio e vitamina D, exercícios físicos, uso de bifosfonatos, denosumab, e moduladores seletivos do receptor de estrogênio. Conclusão: pessoas com maior risco de desenvolver câncer também possuem maior risco de osteopenia e osteoporose, quando processo já estabelecido e em tratamento antineoplásico, devido ao compartilhamento de fatores de risco. Torna-se evidente a necessidade da densitometria óssea nos pacientes em tratamento contra o câncer para de prevenção e promoção de saúde óssea nesses pacientes, além de mais pesquisas com alto nivel de evidência para subsidiar tal uso.Hospital de Clínicas de Itajubá2023-09-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer reviewedAvaliado pelos parestextoinfo:eu-repo/semantics/otherapplication/pdfapplication/pdfhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/144210.21876/rcshci.v13i3.1442Health Sciences Journal; v. 13 n. 3 (2023): Julho a Setembro de 2023; 56-65Health Sciences Journal; Vol 13 No 3 (2023): July to September 2023; 56-6510.21876/rcshci.v13i3reponame:Revista Ciências em Saúdeinstname:Hospital de Clínicas de Itajubáinstacron:HCIengporhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442/897https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442/898Copyright (c) 2023 Health Sciences Journalhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessRezende, Lucas Dalvi ArmondCatabriga, Davi de SouzaPansini, Karielly GasperazzoReis, Mateus Gonçalves Prata dosFreitas, Paula de Souza SilvaFiorin, Bruno Henrique2023-09-22T14:23:35Zoai:ojs.portalrcs.hcitajuba.org.br:article/1442Revistahttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zeroPUBhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/oaircs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br2236-37852236-3785opendoar:2023-09-22T14:23:35Revista Ciências em Saúde - Hospital de Clínicas de Itajubáfalse |
dc.title.none.fl_str_mv |
Osteometabolic changes in patients under antineoplastic treatment: scoping review Alterações osteometabólicas em pacientes em tratamento antineoplásico: revisão de escopo |
title |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
spellingShingle |
Osteometabolic changes in patients under antineoplastic treatment: scoping review Rezende, Lucas Dalvi Armond Antineoplastics Bones Chemotherapy Metabolic bone diseases Oncology Antineoplásicos Doenças ósseas metabólicas Oncologia Ossos Quimioterapia |
title_short |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
title_full |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
title_fullStr |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
title_full_unstemmed |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
title_sort |
Osteometabolic changes in patients under antineoplastic treatment: scoping review |
author |
Rezende, Lucas Dalvi Armond |
author_facet |
Rezende, Lucas Dalvi Armond Catabriga, Davi de Souza Pansini, Karielly Gasperazzo Reis, Mateus Gonçalves Prata dos Freitas, Paula de Souza Silva Fiorin, Bruno Henrique |
author_role |
author |
author2 |
Catabriga, Davi de Souza Pansini, Karielly Gasperazzo Reis, Mateus Gonçalves Prata dos Freitas, Paula de Souza Silva Fiorin, Bruno Henrique |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Rezende, Lucas Dalvi Armond Catabriga, Davi de Souza Pansini, Karielly Gasperazzo Reis, Mateus Gonçalves Prata dos Freitas, Paula de Souza Silva Fiorin, Bruno Henrique |
dc.subject.por.fl_str_mv |
Antineoplastics Bones Chemotherapy Metabolic bone diseases Oncology Antineoplásicos Doenças ósseas metabólicas Oncologia Ossos Quimioterapia |
topic |
Antineoplastics Bones Chemotherapy Metabolic bone diseases Oncology Antineoplásicos Doenças ósseas metabólicas Oncologia Ossos Quimioterapia |
description |
Objective: To summarize the main evidence regarding osteometabolic changes in patients undergoing antineoplastic treatment. Methods: This is a scoping review, following the methodology of the Joanna Briggs Institute, using PubMed/MedLine, Cochrane Library, LILACS, The British Library, and Google Scholar. This review is registered in the Open Science Framework. Results: Many antineoplastics affect bone architecture by reducing its density, such as selective estrogen receptor modulators, aromatase inhibitors, androgen deprivation therapy, and glucocorticoids. To avoid such outcomes, treatment and prevention can be achieved by calcium and vitamin D supplementation, physical exercise, use of bisphosphonates, denosumab, and selective estrogen receptor modulators. Conclusion: people at a higher risk of developing cancer also have a higher risk of osteopenia and osteoporosis when the process is already established and undergoing antineoplastic treatment because of the grouping of risk factors. The need for bone densitometry in patients undergoing cancer treatment to prevent and promote bone health in these patients is evident, in addition to more research with a high level of evidence to support such use. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer reviewed Avaliado pelos pares texto info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442 10.21876/rcshci.v13i3.1442 |
url |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442 |
identifier_str_mv |
10.21876/rcshci.v13i3.1442 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442/897 https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1442/898 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Health Sciences Journal https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Health Sciences Journal https://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Hospital de Clínicas de Itajubá |
publisher.none.fl_str_mv |
Hospital de Clínicas de Itajubá |
dc.source.none.fl_str_mv |
Health Sciences Journal; v. 13 n. 3 (2023): Julho a Setembro de 2023; 56-65 Health Sciences Journal; Vol 13 No 3 (2023): July to September 2023; 56-65 10.21876/rcshci.v13i3 reponame:Revista Ciências em Saúde instname:Hospital de Clínicas de Itajubá instacron:HCI |
instname_str |
Hospital de Clínicas de Itajubá |
instacron_str |
HCI |
institution |
HCI |
reponame_str |
Revista Ciências em Saúde |
collection |
Revista Ciências em Saúde |
repository.name.fl_str_mv |
Revista Ciências em Saúde - Hospital de Clínicas de Itajubá |
repository.mail.fl_str_mv |
rcs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br |
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1797068960344047616 |