The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2

Detalhes bibliográficos
Autor(a) principal: Vigário,Larissa Carvalho
Data de Publicação: 2022
Outros Autores: Muradas,Guilherme, Paiva,Claudia Neto, Medei,Emiliano
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Journal of Cardiovascular Sciences (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472022000300410
Resumo: Abstract An acute respiratory syndrome caused by SARS-CoV2 was declared a pandemic by the World Health Organization. Current data in the world and in Brazil show that approximately 40% of patients who died have some type of cardiac comorbidity. There are also robust reports showing an increase in IL-6 / IL-1B / TNF-alpha and the presence of lymphopenia in patients with COVID-19. Our team and others have shown that increased cytokines are the link between arrhythmias/Left ventricular dysfunction and the immune system in different diseases. In addition, it has been well demonstrated that lymphopenia can not only be a good marker, but also a factor that causes heart failure. Thus, the present review focused on the role of the immune system upon the cardiac alterations observed in the SARS-CoV2 infection. Additionally, it was well described that SARS-CoV-2 is able to infect cardiac cells. Therefore, here it will be reviewed in deep.
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spelling The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2SARS-CoV2Heart/immunologySevere Acute Respiratory SyndromeCoronavirus/ complicationsHeart Diseases/ complicationsAbstract An acute respiratory syndrome caused by SARS-CoV2 was declared a pandemic by the World Health Organization. Current data in the world and in Brazil show that approximately 40% of patients who died have some type of cardiac comorbidity. There are also robust reports showing an increase in IL-6 / IL-1B / TNF-alpha and the presence of lymphopenia in patients with COVID-19. Our team and others have shown that increased cytokines are the link between arrhythmias/Left ventricular dysfunction and the immune system in different diseases. In addition, it has been well demonstrated that lymphopenia can not only be a good marker, but also a factor that causes heart failure. Thus, the present review focused on the role of the immune system upon the cardiac alterations observed in the SARS-CoV2 infection. Additionally, it was well described that SARS-CoV-2 is able to infect cardiac cells. Therefore, here it will be reviewed in deep.Sociedade Brasileira de Cardiologia2022-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472022000300410International Journal of Cardiovascular Sciences v.35 n.3 2022reponame:International Journal of Cardiovascular Sciences (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.36660/ijcs.20200266info:eu-repo/semantics/openAccessVigário,Larissa CarvalhoMuradas,GuilhermePaiva,Claudia NetoMedei,Emilianoeng2022-05-09T00:00:00Zoai:scielo:S2359-56472022000300410Revistahttp://publicacoes.cardiol.br/portal/ijcshttps://old.scielo.br/oai/scielo-oai.phptailanerodrigues@cardiol.br||revistaijcs@cardiol.br2359-56472359-4802opendoar:2022-05-09T00:00International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC)false
dc.title.none.fl_str_mv The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
title The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
spellingShingle The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
Vigário,Larissa Carvalho
SARS-CoV2
Heart/immunology
Severe Acute Respiratory Syndrome
Coronavirus/ complications
Heart Diseases/ complications
title_short The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
title_full The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
title_fullStr The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
title_full_unstemmed The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
title_sort The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
author Vigário,Larissa Carvalho
author_facet Vigário,Larissa Carvalho
Muradas,Guilherme
Paiva,Claudia Neto
Medei,Emiliano
author_role author
author2 Muradas,Guilherme
Paiva,Claudia Neto
Medei,Emiliano
author2_role author
author
author
dc.contributor.author.fl_str_mv Vigário,Larissa Carvalho
Muradas,Guilherme
Paiva,Claudia Neto
Medei,Emiliano
dc.subject.por.fl_str_mv SARS-CoV2
Heart/immunology
Severe Acute Respiratory Syndrome
Coronavirus/ complications
Heart Diseases/ complications
topic SARS-CoV2
Heart/immunology
Severe Acute Respiratory Syndrome
Coronavirus/ complications
Heart Diseases/ complications
description Abstract An acute respiratory syndrome caused by SARS-CoV2 was declared a pandemic by the World Health Organization. Current data in the world and in Brazil show that approximately 40% of patients who died have some type of cardiac comorbidity. There are also robust reports showing an increase in IL-6 / IL-1B / TNF-alpha and the presence of lymphopenia in patients with COVID-19. Our team and others have shown that increased cytokines are the link between arrhythmias/Left ventricular dysfunction and the immune system in different diseases. In addition, it has been well demonstrated that lymphopenia can not only be a good marker, but also a factor that causes heart failure. Thus, the present review focused on the role of the immune system upon the cardiac alterations observed in the SARS-CoV2 infection. Additionally, it was well described that SARS-CoV-2 is able to infect cardiac cells. Therefore, here it will be reviewed in deep.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472022000300410
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472022000300410
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.36660/ijcs.20200266
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia
dc.source.none.fl_str_mv International Journal of Cardiovascular Sciences v.35 n.3 2022
reponame:International Journal of Cardiovascular Sciences (Online)
instname:Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
instname_str Sociedade Brasileira de Cardiologia (SBC)
instacron_str SBC
institution SBC
reponame_str International Journal of Cardiovascular Sciences (Online)
collection International Journal of Cardiovascular Sciences (Online)
repository.name.fl_str_mv International Journal of Cardiovascular Sciences (Online) - Sociedade Brasileira de Cardiologia (SBC)
repository.mail.fl_str_mv tailanerodrigues@cardiol.br||revistaijcs@cardiol.br
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