Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion

Detalhes bibliográficos
Autor(a) principal: Scolaro,Bruno Lorenzo
Data de Publicação: 2017
Outros Autores: Pereira,Gustavo Becker, Ogata,Daniel Cury, Cunha,Fernanda Souto Padrón Figueiredo Vieira da, Effting,Ana Cristina Martins, Guanabara,Rafael Oselame
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632017000300242
Resumo: Abstract Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation. Diagnostic confirmation is done through immunohistochemistry. As therapeutic options, topical corticosteroids and chemotherapy are good choices. The case is reported of a male patient, aged 14, with perianal ulceration. He consulted a coloproctologist, who performed a biopsy of the region and started local triamcinolone applications. Immunohistochemistry diagnosed Langerhans’ cells histiocytosis. Further investigation revealed diabetes insipidus, osteolytic lesions in the skull and lower limbs, enlarged liver, and encephalic alterations. Chemotherapy was started with Vinblastine, with significant improvement of the lesions.
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spelling Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesionCD1 antigensLangerhans’ cellsLangerhans’ cell histiocytosisHistiocytosis XVinblastineAbstract Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation. Diagnostic confirmation is done through immunohistochemistry. As therapeutic options, topical corticosteroids and chemotherapy are good choices. The case is reported of a male patient, aged 14, with perianal ulceration. He consulted a coloproctologist, who performed a biopsy of the region and started local triamcinolone applications. Immunohistochemistry diagnosed Langerhans’ cells histiocytosis. Further investigation revealed diabetes insipidus, osteolytic lesions in the skull and lower limbs, enlarged liver, and encephalic alterations. Chemotherapy was started with Vinblastine, with significant improvement of the lesions.Sociedade Brasileira de Coloproctologia2017-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632017000300242Journal of Coloproctology (Rio de Janeiro) v.37 n.3 2017reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2017.03.007info:eu-repo/semantics/openAccessScolaro,Bruno LorenzoPereira,Gustavo BeckerOgata,Daniel CuryCunha,Fernanda Souto Padrón Figueiredo Vieira daEffting,Ana Cristina MartinsGuanabara,Rafael Oselameeng2017-08-23T00:00:00Zoai:scielo:S2237-93632017000300242Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2017-08-23T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
title Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
spellingShingle Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
Scolaro,Bruno Lorenzo
CD1 antigens
Langerhans’ cells
Langerhans’ cell histiocytosis
Histiocytosis X
Vinblastine
title_short Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
title_full Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
title_fullStr Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
title_full_unstemmed Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
title_sort Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion
author Scolaro,Bruno Lorenzo
author_facet Scolaro,Bruno Lorenzo
Pereira,Gustavo Becker
Ogata,Daniel Cury
Cunha,Fernanda Souto Padrón Figueiredo Vieira da
Effting,Ana Cristina Martins
Guanabara,Rafael Oselame
author_role author
author2 Pereira,Gustavo Becker
Ogata,Daniel Cury
Cunha,Fernanda Souto Padrón Figueiredo Vieira da
Effting,Ana Cristina Martins
Guanabara,Rafael Oselame
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Scolaro,Bruno Lorenzo
Pereira,Gustavo Becker
Ogata,Daniel Cury
Cunha,Fernanda Souto Padrón Figueiredo Vieira da
Effting,Ana Cristina Martins
Guanabara,Rafael Oselame
dc.subject.por.fl_str_mv CD1 antigens
Langerhans’ cells
Langerhans’ cell histiocytosis
Histiocytosis X
Vinblastine
topic CD1 antigens
Langerhans’ cells
Langerhans’ cell histiocytosis
Histiocytosis X
Vinblastine
description Abstract Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation. Diagnostic confirmation is done through immunohistochemistry. As therapeutic options, topical corticosteroids and chemotherapy are good choices. The case is reported of a male patient, aged 14, with perianal ulceration. He consulted a coloproctologist, who performed a biopsy of the region and started local triamcinolone applications. Immunohistochemistry diagnosed Langerhans’ cells histiocytosis. Further investigation revealed diabetes insipidus, osteolytic lesions in the skull and lower limbs, enlarged liver, and encephalic alterations. Chemotherapy was started with Vinblastine, with significant improvement of the lesions.
publishDate 2017
dc.date.none.fl_str_mv 2017-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632017000300242
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632017000300242
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2017.03.007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.37 n.3 2017
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
institution SBCP
reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
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