Safety assessment of Spirulina platensis through sprague dawley rats modeling
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Food Science and Technology (Campinas) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376 |
Resumo: | Abstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries. |
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Food Science and Technology (Campinas) |
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Safety assessment of Spirulina platensis through sprague dawley rats modelingspirulinaspirulina protein isolateshematologyhistopathologyalgal toxicologyAbstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2020-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376Food Science and Technology v.40 n.2 2020reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.41918info:eu-repo/semantics/openAccessBASHIR,ShahidSHARIF,Mian KamranJAVED,Muhammad SameemAMJAD,AdnanKHAN,Ammar AhmadSHAH,Faiz-ul-HassanKHALIL,Anees Ahmadeng2020-05-27T00:00:00Zoai:scielo:S0101-20612020000200376Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2020-05-27T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false |
dc.title.none.fl_str_mv |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
title |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
spellingShingle |
Safety assessment of Spirulina platensis through sprague dawley rats modeling BASHIR,Shahid spirulina spirulina protein isolates hematology histopathology algal toxicology |
title_short |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
title_full |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
title_fullStr |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
title_full_unstemmed |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
title_sort |
Safety assessment of Spirulina platensis through sprague dawley rats modeling |
author |
BASHIR,Shahid |
author_facet |
BASHIR,Shahid SHARIF,Mian Kamran JAVED,Muhammad Sameem AMJAD,Adnan KHAN,Ammar Ahmad SHAH,Faiz-ul-Hassan KHALIL,Anees Ahmad |
author_role |
author |
author2 |
SHARIF,Mian Kamran JAVED,Muhammad Sameem AMJAD,Adnan KHAN,Ammar Ahmad SHAH,Faiz-ul-Hassan KHALIL,Anees Ahmad |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
BASHIR,Shahid SHARIF,Mian Kamran JAVED,Muhammad Sameem AMJAD,Adnan KHAN,Ammar Ahmad SHAH,Faiz-ul-Hassan KHALIL,Anees Ahmad |
dc.subject.por.fl_str_mv |
spirulina spirulina protein isolates hematology histopathology algal toxicology |
topic |
spirulina spirulina protein isolates hematology histopathology algal toxicology |
description |
Abstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/fst.41918 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
dc.source.none.fl_str_mv |
Food Science and Technology v.40 n.2 2020 reponame:Food Science and Technology (Campinas) instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) instacron:SBCTA |
instname_str |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
instacron_str |
SBCTA |
institution |
SBCTA |
reponame_str |
Food Science and Technology (Campinas) |
collection |
Food Science and Technology (Campinas) |
repository.name.fl_str_mv |
Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
repository.mail.fl_str_mv |
||revista@sbcta.org.br |
_version_ |
1752126325644066816 |