Safety assessment of Spirulina platensis through sprague dawley rats modeling

Detalhes bibliográficos
Autor(a) principal: BASHIR,Shahid
Data de Publicação: 2020
Outros Autores: SHARIF,Mian Kamran, JAVED,Muhammad Sameem, AMJAD,Adnan, KHAN,Ammar Ahmad, SHAH,Faiz-ul-Hassan, KHALIL,Anees Ahmad
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Food Science and Technology (Campinas)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376
Resumo: Abstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries.
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spelling Safety assessment of Spirulina platensis through sprague dawley rats modelingspirulinaspirulina protein isolateshematologyhistopathologyalgal toxicologyAbstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2020-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376Food Science and Technology v.40 n.2 2020reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.41918info:eu-repo/semantics/openAccessBASHIR,ShahidSHARIF,Mian KamranJAVED,Muhammad SameemAMJAD,AdnanKHAN,Ammar AhmadSHAH,Faiz-ul-HassanKHALIL,Anees Ahmadeng2020-05-27T00:00:00Zoai:scielo:S0101-20612020000200376Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2020-05-27T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false
dc.title.none.fl_str_mv Safety assessment of Spirulina platensis through sprague dawley rats modeling
title Safety assessment of Spirulina platensis through sprague dawley rats modeling
spellingShingle Safety assessment of Spirulina platensis through sprague dawley rats modeling
BASHIR,Shahid
spirulina
spirulina protein isolates
hematology
histopathology
algal toxicology
title_short Safety assessment of Spirulina platensis through sprague dawley rats modeling
title_full Safety assessment of Spirulina platensis through sprague dawley rats modeling
title_fullStr Safety assessment of Spirulina platensis through sprague dawley rats modeling
title_full_unstemmed Safety assessment of Spirulina platensis through sprague dawley rats modeling
title_sort Safety assessment of Spirulina platensis through sprague dawley rats modeling
author BASHIR,Shahid
author_facet BASHIR,Shahid
SHARIF,Mian Kamran
JAVED,Muhammad Sameem
AMJAD,Adnan
KHAN,Ammar Ahmad
SHAH,Faiz-ul-Hassan
KHALIL,Anees Ahmad
author_role author
author2 SHARIF,Mian Kamran
JAVED,Muhammad Sameem
AMJAD,Adnan
KHAN,Ammar Ahmad
SHAH,Faiz-ul-Hassan
KHALIL,Anees Ahmad
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv BASHIR,Shahid
SHARIF,Mian Kamran
JAVED,Muhammad Sameem
AMJAD,Adnan
KHAN,Ammar Ahmad
SHAH,Faiz-ul-Hassan
KHALIL,Anees Ahmad
dc.subject.por.fl_str_mv spirulina
spirulina protein isolates
hematology
histopathology
algal toxicology
topic spirulina
spirulina protein isolates
hematology
histopathology
algal toxicology
description Abstract Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000200376
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/fst.41918
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ciência e Tecnologia de Alimentos
publisher.none.fl_str_mv Sociedade Brasileira de Ciência e Tecnologia de Alimentos
dc.source.none.fl_str_mv Food Science and Technology v.40 n.2 2020
reponame:Food Science and Technology (Campinas)
instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
instname_str Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron_str SBCTA
institution SBCTA
reponame_str Food Science and Technology (Campinas)
collection Food Science and Technology (Campinas)
repository.name.fl_str_mv Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
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