The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Food Science and Technology (Campinas) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101349 |
Resumo: | Abstract Feixingcao tea is a health tea, and this study aimed to investigate its improvement in the decreased exercise capacity caused by chronic alcoholic liver injury. A mouse model of chronic liver injury was established by gavage of alcohol, and Feixingcao tea extract (FXCTE) was used to observe the exercise ability, pathological sections and molecular biology methods to detect the effect of FXCTE. And the active ingredient of FXCTE is detected by HPLC. Experimental results showed that FXCTE could increase the time of exhaustive running and negative-gravity swimming in mice with liver injury. FXCTE could reduce alcohol-induced liver lesions. FXCTE could reduce the levels of Lactic acid, BUN, GOT, GPT, TNF-α and iNOS in serum of mice with liver injury. FXCTE could also up-regulate the mRNA expression of Cu/Zn-SOD, Mn-SOD, CAT and down-regulate the expression of nNOS, syncytin-1 in liver injury mice. Component analysis showed that FXCTE contained mangiferin, rutin, ferulic acid, isochlorogenic acid B, astragalin, rosmarinic acid. FXCTE is a health-care tea containing a variety of active compounds, which can improve chronic alcoholic liver damage and improve the decline in exercise ability caused by liver damage. |
id |
SBCTA-1_bcfb681636acb7ae7da8240ade7e87fa |
---|---|
oai_identifier_str |
oai:scielo:S0101-20612022000101349 |
network_acronym_str |
SBCTA-1 |
network_name_str |
Food Science and Technology (Campinas) |
repository_id_str |
|
spelling |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injuryFeixingcao teachronic alcoholic liver injuryexercise abilityoxidationliverAbstract Feixingcao tea is a health tea, and this study aimed to investigate its improvement in the decreased exercise capacity caused by chronic alcoholic liver injury. A mouse model of chronic liver injury was established by gavage of alcohol, and Feixingcao tea extract (FXCTE) was used to observe the exercise ability, pathological sections and molecular biology methods to detect the effect of FXCTE. And the active ingredient of FXCTE is detected by HPLC. Experimental results showed that FXCTE could increase the time of exhaustive running and negative-gravity swimming in mice with liver injury. FXCTE could reduce alcohol-induced liver lesions. FXCTE could reduce the levels of Lactic acid, BUN, GOT, GPT, TNF-α and iNOS in serum of mice with liver injury. FXCTE could also up-regulate the mRNA expression of Cu/Zn-SOD, Mn-SOD, CAT and down-regulate the expression of nNOS, syncytin-1 in liver injury mice. Component analysis showed that FXCTE contained mangiferin, rutin, ferulic acid, isochlorogenic acid B, astragalin, rosmarinic acid. FXCTE is a health-care tea containing a variety of active compounds, which can improve chronic alcoholic liver damage and improve the decline in exercise ability caused by liver damage.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101349Food Science and Technology v.42 2022reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.80822info:eu-repo/semantics/openAccessWANG,Yaneng2022-10-10T00:00:00Zoai:scielo:S0101-20612022000101349Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2022-10-10T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false |
dc.title.none.fl_str_mv |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
title |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
spellingShingle |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury WANG,Yan Feixingcao tea chronic alcoholic liver injury exercise ability oxidation liver |
title_short |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
title_full |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
title_fullStr |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
title_full_unstemmed |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
title_sort |
The recovery effect of Feixingcao tea (Teucrium viscidum Bl.) on inhibiting the decreased exercise ability caused by chronic alcoholic liver injury |
author |
WANG,Yan |
author_facet |
WANG,Yan |
author_role |
author |
dc.contributor.author.fl_str_mv |
WANG,Yan |
dc.subject.por.fl_str_mv |
Feixingcao tea chronic alcoholic liver injury exercise ability oxidation liver |
topic |
Feixingcao tea chronic alcoholic liver injury exercise ability oxidation liver |
description |
Abstract Feixingcao tea is a health tea, and this study aimed to investigate its improvement in the decreased exercise capacity caused by chronic alcoholic liver injury. A mouse model of chronic liver injury was established by gavage of alcohol, and Feixingcao tea extract (FXCTE) was used to observe the exercise ability, pathological sections and molecular biology methods to detect the effect of FXCTE. And the active ingredient of FXCTE is detected by HPLC. Experimental results showed that FXCTE could increase the time of exhaustive running and negative-gravity swimming in mice with liver injury. FXCTE could reduce alcohol-induced liver lesions. FXCTE could reduce the levels of Lactic acid, BUN, GOT, GPT, TNF-α and iNOS in serum of mice with liver injury. FXCTE could also up-regulate the mRNA expression of Cu/Zn-SOD, Mn-SOD, CAT and down-regulate the expression of nNOS, syncytin-1 in liver injury mice. Component analysis showed that FXCTE contained mangiferin, rutin, ferulic acid, isochlorogenic acid B, astragalin, rosmarinic acid. FXCTE is a health-care tea containing a variety of active compounds, which can improve chronic alcoholic liver damage and improve the decline in exercise ability caused by liver damage. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101349 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101349 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/fst.80822 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
dc.source.none.fl_str_mv |
Food Science and Technology v.42 2022 reponame:Food Science and Technology (Campinas) instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) instacron:SBCTA |
instname_str |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
instacron_str |
SBCTA |
institution |
SBCTA |
reponame_str |
Food Science and Technology (Campinas) |
collection |
Food Science and Technology (Campinas) |
repository.name.fl_str_mv |
Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
repository.mail.fl_str_mv |
||revista@sbcta.org.br |
_version_ |
1752126335445106688 |