Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy

Detalhes bibliográficos
Autor(a) principal: Nery,Jose Augusto da Costa
Data de Publicação: 2013
Outros Autores: Bernardes Filho,Fred, Quintanilha,Juliana, Machado,Alice Miranda, Oliveira,Soraya de Souza Chantre, Sales,Anna Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000500787
Resumo: A type 1 reaction or reversal reaction is expressed clinically by inflammatory exacerbation of the skin lesions and nerve trunks, consequently leading to sensory and motor alterations. It occurs in non-polar forms of leprosy, although it can occur in a small percentage of sub-polar LL treated patients. Disabilities, deformities and morbidity, still present in leprosy, are mainly caused by these acute episodes. The recognition of reactional states is imperative for an early approach and efficient management, to avoid the emergence of disabilities that stigmatize the disease. This review aims to describe the clinical aspects, immunopathogenesis, epidemiology, histopathological features and therapeutics of type 1 reactions.
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spelling Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosyErythema nodosumLeprosyLeprosy, multibacillaryLeprosy, paucibacillaryMycobacterium lepraeA type 1 reaction or reversal reaction is expressed clinically by inflammatory exacerbation of the skin lesions and nerve trunks, consequently leading to sensory and motor alterations. It occurs in non-polar forms of leprosy, although it can occur in a small percentage of sub-polar LL treated patients. Disabilities, deformities and morbidity, still present in leprosy, are mainly caused by these acute episodes. The recognition of reactional states is imperative for an early approach and efficient management, to avoid the emergence of disabilities that stigmatize the disease. This review aims to describe the clinical aspects, immunopathogenesis, epidemiology, histopathological features and therapeutics of type 1 reactions.Sociedade Brasileira de Dermatologia2013-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000500787Anais Brasileiros de Dermatologia v.88 n.5 2013reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20132004info:eu-repo/semantics/openAccessNery,Jose Augusto da CostaBernardes Filho,FredQuintanilha,JulianaMachado,Alice MirandaOliveira,Soraya de Souza ChantreSales,Anna Mariaeng2013-10-28T00:00:00Zoai:scielo:S0365-05962013000500787Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2013-10-28T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
title Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
spellingShingle Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
Nery,Jose Augusto da Costa
Erythema nodosum
Leprosy
Leprosy, multibacillary
Leprosy, paucibacillary
Mycobacterium leprae
title_short Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
title_full Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
title_fullStr Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
title_full_unstemmed Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
title_sort Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy
author Nery,Jose Augusto da Costa
author_facet Nery,Jose Augusto da Costa
Bernardes Filho,Fred
Quintanilha,Juliana
Machado,Alice Miranda
Oliveira,Soraya de Souza Chantre
Sales,Anna Maria
author_role author
author2 Bernardes Filho,Fred
Quintanilha,Juliana
Machado,Alice Miranda
Oliveira,Soraya de Souza Chantre
Sales,Anna Maria
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Nery,Jose Augusto da Costa
Bernardes Filho,Fred
Quintanilha,Juliana
Machado,Alice Miranda
Oliveira,Soraya de Souza Chantre
Sales,Anna Maria
dc.subject.por.fl_str_mv Erythema nodosum
Leprosy
Leprosy, multibacillary
Leprosy, paucibacillary
Mycobacterium leprae
topic Erythema nodosum
Leprosy
Leprosy, multibacillary
Leprosy, paucibacillary
Mycobacterium leprae
description A type 1 reaction or reversal reaction is expressed clinically by inflammatory exacerbation of the skin lesions and nerve trunks, consequently leading to sensory and motor alterations. It occurs in non-polar forms of leprosy, although it can occur in a small percentage of sub-polar LL treated patients. Disabilities, deformities and morbidity, still present in leprosy, are mainly caused by these acute episodes. The recognition of reactional states is imperative for an early approach and efficient management, to avoid the emergence of disabilities that stigmatize the disease. This review aims to describe the clinical aspects, immunopathogenesis, epidemiology, histopathological features and therapeutics of type 1 reactions.
publishDate 2013
dc.date.none.fl_str_mv 2013-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000500787
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000500787
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20132004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.88 n.5 2013
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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