Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats

Detalhes bibliográficos
Autor(a) principal: Biancon Filho,Luiz Alberto
Data de Publicação: 2011
Outros Autores: Primo,Bruno Tochetto, Gassen,Humberto Thomazi, Fontanella,Vânia Regina Camargo, Silva Jr,Aurelício Novaes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000100002
Resumo: Purpose: To evaluate new bone formation, by the analysis of optical density, in rat femoral defects filled with calcium phosphate cement (CPC) and bioactive glass (BG). Methods: Twenty-one rats were divided into three groups, Group I (CPC), Group II (BG), and Group III (control), and assessed after 7, 15, and 30 days. Three bone cavities were made in the left femur and filled with CPC, BG, and no material (control). Digital images were obtained and the results were subjected to statistical analysis of variance (ANOVA), complemented by the Friedman and Kruskal-Wallis nonparametric tests, with a significance level of 5%. Results: Regarding optical density, Group I showed statistical values significantly higher than Group III and also higher, although not statistically significant, than Group II, in all observation periods. When Groups II and III were compared, Group II showed higher optical density values, without statistically significant differences, in all periods. Conclusion: The biomaterials analyzed showed higher optical density in relation to the control group in all observation periods, calcium phosphate cement being the best option in the repair of bone defects, but without statistically significant differences in relation to bioactive glass.
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spelling Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in ratsBone SubstitutesBiocompatible MaterialsBone TransplantationBone RegenerationRatsPurpose: To evaluate new bone formation, by the analysis of optical density, in rat femoral defects filled with calcium phosphate cement (CPC) and bioactive glass (BG). Methods: Twenty-one rats were divided into three groups, Group I (CPC), Group II (BG), and Group III (control), and assessed after 7, 15, and 30 days. Three bone cavities were made in the left femur and filled with CPC, BG, and no material (control). Digital images were obtained and the results were subjected to statistical analysis of variance (ANOVA), complemented by the Friedman and Kruskal-Wallis nonparametric tests, with a significance level of 5%. Results: Regarding optical density, Group I showed statistical values significantly higher than Group III and also higher, although not statistically significant, than Group II, in all observation periods. When Groups II and III were compared, Group II showed higher optical density values, without statistically significant differences, in all periods. Conclusion: The biomaterials analyzed showed higher optical density in relation to the control group in all observation periods, calcium phosphate cement being the best option in the repair of bone defects, but without statistically significant differences in relation to bioactive glass.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000100002Acta Cirúrgica Brasileira v.26 n.1 2011reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502011000100002info:eu-repo/semantics/openAccessBiancon Filho,Luiz AlbertoPrimo,Bruno TochettoGassen,Humberto ThomaziFontanella,Vânia Regina CamargoSilva Jr,Aurelício Novaeseng2011-01-20T00:00:00Zoai:scielo:S0102-86502011000100002Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2011-01-20T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
title Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
spellingShingle Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
Biancon Filho,Luiz Alberto
Bone Substitutes
Biocompatible Materials
Bone Transplantation
Bone Regeneration
Rats
title_short Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
title_full Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
title_fullStr Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
title_full_unstemmed Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
title_sort Evaluation of optical density of bone defects filled with calcium phosphate cement and bioactive glass in rats
author Biancon Filho,Luiz Alberto
author_facet Biancon Filho,Luiz Alberto
Primo,Bruno Tochetto
Gassen,Humberto Thomazi
Fontanella,Vânia Regina Camargo
Silva Jr,Aurelício Novaes
author_role author
author2 Primo,Bruno Tochetto
Gassen,Humberto Thomazi
Fontanella,Vânia Regina Camargo
Silva Jr,Aurelício Novaes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Biancon Filho,Luiz Alberto
Primo,Bruno Tochetto
Gassen,Humberto Thomazi
Fontanella,Vânia Regina Camargo
Silva Jr,Aurelício Novaes
dc.subject.por.fl_str_mv Bone Substitutes
Biocompatible Materials
Bone Transplantation
Bone Regeneration
Rats
topic Bone Substitutes
Biocompatible Materials
Bone Transplantation
Bone Regeneration
Rats
description Purpose: To evaluate new bone formation, by the analysis of optical density, in rat femoral defects filled with calcium phosphate cement (CPC) and bioactive glass (BG). Methods: Twenty-one rats were divided into three groups, Group I (CPC), Group II (BG), and Group III (control), and assessed after 7, 15, and 30 days. Three bone cavities were made in the left femur and filled with CPC, BG, and no material (control). Digital images were obtained and the results were subjected to statistical analysis of variance (ANOVA), complemented by the Friedman and Kruskal-Wallis nonparametric tests, with a significance level of 5%. Results: Regarding optical density, Group I showed statistical values significantly higher than Group III and also higher, although not statistically significant, than Group II, in all observation periods. When Groups II and III were compared, Group II showed higher optical density values, without statistically significant differences, in all periods. Conclusion: The biomaterials analyzed showed higher optical density in relation to the control group in all observation periods, calcium phosphate cement being the best option in the repair of bone defects, but without statistically significant differences in relation to bioactive glass.
publishDate 2011
dc.date.none.fl_str_mv 2011-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000100002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502011000100002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.26 n.1 2011
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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