Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate

Detalhes bibliográficos
Autor(a) principal: Pegorare,Ana Beatriz Gomes de Souza
Data de Publicação: 2014
Outros Autores: Gonçalves,Marco Antonio, Oliveira,Alessandra Martiniano de, Rodrigues Junior,Antonio Antunes, Tucci Jr,Silvio, Suaid,Haylton Jorge
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000400274
Resumo: PURPOSE: To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function.METHODS: Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously.RESULTS: A significant increase in urethral pressure was observed during micturition.CONCLUSION: Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.
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spelling Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrateDiabetes MellitusUrethraUrinary BladderRatsPURPOSE: To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function.METHODS: Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously.RESULTS: A significant increase in urethral pressure was observed during micturition.CONCLUSION: Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2014-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000400274Acta Cirúrgica Brasileira v.29 n.4 2014reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502014000400009info:eu-repo/semantics/openAccessPegorare,Ana Beatriz Gomes de SouzaGonçalves,Marco AntonioOliveira,Alessandra Martiniano deRodrigues Junior,Antonio AntunesTucci Jr,SilvioSuaid,Haylton Jorgeeng2015-10-08T00:00:00Zoai:scielo:S0102-86502014000400274Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2015-10-08T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
title Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
spellingShingle Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
Pegorare,Ana Beatriz Gomes de Souza
Diabetes Mellitus
Urethra
Urinary Bladder
Rats
title_short Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
title_full Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
title_fullStr Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
title_full_unstemmed Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
title_sort Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
author Pegorare,Ana Beatriz Gomes de Souza
author_facet Pegorare,Ana Beatriz Gomes de Souza
Gonçalves,Marco Antonio
Oliveira,Alessandra Martiniano de
Rodrigues Junior,Antonio Antunes
Tucci Jr,Silvio
Suaid,Haylton Jorge
author_role author
author2 Gonçalves,Marco Antonio
Oliveira,Alessandra Martiniano de
Rodrigues Junior,Antonio Antunes
Tucci Jr,Silvio
Suaid,Haylton Jorge
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pegorare,Ana Beatriz Gomes de Souza
Gonçalves,Marco Antonio
Oliveira,Alessandra Martiniano de
Rodrigues Junior,Antonio Antunes
Tucci Jr,Silvio
Suaid,Haylton Jorge
dc.subject.por.fl_str_mv Diabetes Mellitus
Urethra
Urinary Bladder
Rats
topic Diabetes Mellitus
Urethra
Urinary Bladder
Rats
description PURPOSE: To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function.METHODS: Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously.RESULTS: A significant increase in urethral pressure was observed during micturition.CONCLUSION: Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000400274
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000400274
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502014000400009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.29 n.4 2014
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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