Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review

Detalhes bibliográficos
Autor(a) principal: Rocha Filho,Francisco Dário
Data de Publicação: 2008
Outros Autores: Lima,Gabrielle Gurgel, Ferreira,Francisco V. de Almeida, Lima,Michelle Gurgel, Hissa,Miguel N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302008000900014
Resumo: Capillary thyroid carcinoma (PTC) is the most common neoplasm of thyroid. It usually grows slowly and is clinically indolent, although rare, its aggressive forms with local invasion or distant metastases can occur. Metastatic thyroid carcinoma rarely involves the orbit. We reported an uncommon case of orbital metastasis of PTC. A 66-years-old woman presented proptosis of the right eye. The biopsy of the tumor in orbit revealed metastatic thyroid carcinoma. The ultrasensitive TSH level was 1,34 mUI/L and free T4 level was 1,65 ng/dL. A total thyroidectomy was performed and histopathological analysis of the nodule revealed follicular variant of papillary thyroid carcinoma. Currently, the patient has been receiving palliative chemotherapy with Clodronate Disodium. The importance of the case is due to its unusual presentation, which emerged as a primary clinical manifestation. Although rare, thyroid carcinoma should be suspected in orbit metastasis.
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spelling Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature reviewPapillary thyroid carcinomaOrbital metastasisCapillary thyroid carcinoma (PTC) is the most common neoplasm of thyroid. It usually grows slowly and is clinically indolent, although rare, its aggressive forms with local invasion or distant metastases can occur. Metastatic thyroid carcinoma rarely involves the orbit. We reported an uncommon case of orbital metastasis of PTC. A 66-years-old woman presented proptosis of the right eye. The biopsy of the tumor in orbit revealed metastatic thyroid carcinoma. The ultrasensitive TSH level was 1,34 mUI/L and free T4 level was 1,65 ng/dL. A total thyroidectomy was performed and histopathological analysis of the nodule revealed follicular variant of papillary thyroid carcinoma. Currently, the patient has been receiving palliative chemotherapy with Clodronate Disodium. The importance of the case is due to its unusual presentation, which emerged as a primary clinical manifestation. Although rare, thyroid carcinoma should be suspected in orbit metastasis.Sociedade Brasileira de Endocrinologia e Metabologia2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302008000900014Arquivos Brasileiros de Endocrinologia & Metabologia v.52 n.9 2008reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/S0004-27302008000900014info:eu-repo/semantics/openAccessRocha Filho,Francisco DárioLima,Gabrielle GurgelFerreira,Francisco V. de AlmeidaLima,Michelle GurgelHissa,Miguel N.eng2009-02-02T00:00:00Zoai:scielo:S0004-27302008000900014Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2009-02-02T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
title Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
spellingShingle Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
Rocha Filho,Francisco Dário
Papillary thyroid carcinoma
Orbital metastasis
title_short Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
title_full Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
title_fullStr Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
title_full_unstemmed Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
title_sort Orbital metastasis as primary clinical manifestation of thyroid carcinoma: case report and literature review
author Rocha Filho,Francisco Dário
author_facet Rocha Filho,Francisco Dário
Lima,Gabrielle Gurgel
Ferreira,Francisco V. de Almeida
Lima,Michelle Gurgel
Hissa,Miguel N.
author_role author
author2 Lima,Gabrielle Gurgel
Ferreira,Francisco V. de Almeida
Lima,Michelle Gurgel
Hissa,Miguel N.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rocha Filho,Francisco Dário
Lima,Gabrielle Gurgel
Ferreira,Francisco V. de Almeida
Lima,Michelle Gurgel
Hissa,Miguel N.
dc.subject.por.fl_str_mv Papillary thyroid carcinoma
Orbital metastasis
topic Papillary thyroid carcinoma
Orbital metastasis
description Capillary thyroid carcinoma (PTC) is the most common neoplasm of thyroid. It usually grows slowly and is clinically indolent, although rare, its aggressive forms with local invasion or distant metastases can occur. Metastatic thyroid carcinoma rarely involves the orbit. We reported an uncommon case of orbital metastasis of PTC. A 66-years-old woman presented proptosis of the right eye. The biopsy of the tumor in orbit revealed metastatic thyroid carcinoma. The ultrasensitive TSH level was 1,34 mUI/L and free T4 level was 1,65 ng/dL. A total thyroidectomy was performed and histopathological analysis of the nodule revealed follicular variant of papillary thyroid carcinoma. Currently, the patient has been receiving palliative chemotherapy with Clodronate Disodium. The importance of the case is due to its unusual presentation, which emerged as a primary clinical manifestation. Although rare, thyroid carcinoma should be suspected in orbit metastasis.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302008000900014
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27302008000900014
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia v.52 n.9 2008
reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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collection Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
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