Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara

Detalhes bibliográficos
Autor(a) principal: Maiworm,Adalgisa I.
Data de Publicação: 2008
Outros Autores: Presta,Giuseppe A., Santos-Filho,Sebastião D., Paoli,Severo de, Giani,Tânia S., Fonseca,Adenilson S., Bernardo-Filho,Mario
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010
Resumo: The Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract.
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spelling Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camaraLantana camaraVerbenaceaemorphologyred blood cellsosmotic fragilityThe Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract.Sociedade Brasileira de Farmacognosia2008-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010Revista Brasileira de Farmacognosia v.18 n.1 2008reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2008000100010info:eu-repo/semantics/openAccessMaiworm,Adalgisa I.Presta,Giuseppe A.Santos-Filho,Sebastião D.Paoli,Severo deGiani,Tânia S.Fonseca,Adenilson S.Bernardo-Filho,Marioeng2008-04-14T00:00:00Zoai:scielo:S0102-695X2008000100010Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2008-04-14T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
title Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
spellingShingle Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
Maiworm,Adalgisa I.
Lantana camara
Verbenaceae
morphology
red blood cells
osmotic fragility
title_short Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
title_full Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
title_fullStr Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
title_full_unstemmed Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
title_sort Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
author Maiworm,Adalgisa I.
author_facet Maiworm,Adalgisa I.
Presta,Giuseppe A.
Santos-Filho,Sebastião D.
Paoli,Severo de
Giani,Tânia S.
Fonseca,Adenilson S.
Bernardo-Filho,Mario
author_role author
author2 Presta,Giuseppe A.
Santos-Filho,Sebastião D.
Paoli,Severo de
Giani,Tânia S.
Fonseca,Adenilson S.
Bernardo-Filho,Mario
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Maiworm,Adalgisa I.
Presta,Giuseppe A.
Santos-Filho,Sebastião D.
Paoli,Severo de
Giani,Tânia S.
Fonseca,Adenilson S.
Bernardo-Filho,Mario
dc.subject.por.fl_str_mv Lantana camara
Verbenaceae
morphology
red blood cells
osmotic fragility
topic Lantana camara
Verbenaceae
morphology
red blood cells
osmotic fragility
description The Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2008000100010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.18 n.1 2008
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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