Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010 |
Resumo: | The Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract. |
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Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camaraLantana camaraVerbenaceaemorphologyred blood cellsosmotic fragilityThe Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract.Sociedade Brasileira de Farmacognosia2008-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010Revista Brasileira de Farmacognosia v.18 n.1 2008reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2008000100010info:eu-repo/semantics/openAccessMaiworm,Adalgisa I.Presta,Giuseppe A.Santos-Filho,Sebastião D.Paoli,Severo deGiani,Tânia S.Fonseca,Adenilson S.Bernardo-Filho,Marioeng2008-04-14T00:00:00Zoai:scielo:S0102-695X2008000100010Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2008-04-14T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
title |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
spellingShingle |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara Maiworm,Adalgisa I. Lantana camara Verbenaceae morphology red blood cells osmotic fragility |
title_short |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
title_full |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
title_fullStr |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
title_full_unstemmed |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
title_sort |
Osmotic and morphological effects on red blood cell membrane: action of an aqueous extract of Lantana camara |
author |
Maiworm,Adalgisa I. |
author_facet |
Maiworm,Adalgisa I. Presta,Giuseppe A. Santos-Filho,Sebastião D. Paoli,Severo de Giani,Tânia S. Fonseca,Adenilson S. Bernardo-Filho,Mario |
author_role |
author |
author2 |
Presta,Giuseppe A. Santos-Filho,Sebastião D. Paoli,Severo de Giani,Tânia S. Fonseca,Adenilson S. Bernardo-Filho,Mario |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Maiworm,Adalgisa I. Presta,Giuseppe A. Santos-Filho,Sebastião D. Paoli,Severo de Giani,Tânia S. Fonseca,Adenilson S. Bernardo-Filho,Mario |
dc.subject.por.fl_str_mv |
Lantana camara Verbenaceae morphology red blood cells osmotic fragility |
topic |
Lantana camara Verbenaceae morphology red blood cells osmotic fragility |
description |
The Lantana camara ("cambara de espinho") leaves infusions are used popularly in some countries to treat gastrointestinal diseases. Osmotic fragility assay and morphometric analysis have been used to verify the interaction of drugs with the membrane of red blood cells (RBC). The aim of this work was to evaluate the effects of an aqueous extract of Lantana camara on the osmotic fragility and on the morphology of RBC. Blood samples were treated with extract of Lantana camara (10 mg/mL), osmotic fragility assay and morphological analysis were carried out. In the presence of the extract, the data obtained indicated (i) a significant (p < 0.05) increase of hemolysis and (ii) modifications on the morphology of RBC. These effects of the Lantana camara may be associated with some pharmacological properties of the chemical compounds of this studied extract. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2008000100010 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.18 n.1 2008 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122462922866688 |